In:
Echocardiography, Wiley, Vol. 34, No. 1 ( 2017-01), p. 61-68
Abstract:
Exercise‐induced increase in pulmonary artery systolic pressure ( PASP ) as a possible measure of right ventricular ( RV ) contractile reserve has been shown to predict survival in severe pulmonary hypertension. However, RV contractile reserve can also be measured by changes in stroke volume ( SV ), tricuspid annular plane systolic excursion ( TAPSE ), or tricuspid annular systolic velocity (S'). The limits of normal values and the functional significance of these changes in healthy subjects are not well known. Methods In this prospective study, 90 healthy subjects (45 male, mean age 39 ± 13 years) underwent exercise stress echocardiography with measurement of TAPSE , S', TAPSE / PASP , SV , and PASP at rest and peak exercise. Maximum and minimum normal values were reported for all indices. Results Normal values of exercise‐induced changes (Δ) were 4 to 10 mm for TAPSE , 6 to 14 cm/s for S', 12 to 57 mm Hg for PASP , 0 to 96 mL for SV , and −1.2 to 0 mm/mm Hg for TAPSE / PASP . At peak exercise, women showed lower Δ TAPSE / PASP , Δ PASP , ΔS', and Δ SV , but higher TAPSE / PASP than men. Aging was associated with decreased Δ TAPSE / PASP , Δ TAPSE , ΔS', Δ PASP , and Δ SV . In addition, ΔS', Δ TAPSE / PASP , Δ PASP , and Δ SV , but not Δ TAPSE , were directly correlated with maximum workload. Conclusions Our results provide age‐ and sex‐related limits of normal for RV contractile reserve as assessed by exercise stress echocardiography and demonstrate that RV systolic function indices ( PASP , TAPSE , S', and TAPSE / PASP ) correlate with maximum exercise capacity.
Type of Medium:
Online Resource
ISSN:
0742-2822
,
1540-8175
DOI:
10.1111/echo.2017.34.issue-1
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2041033-5
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