In:
Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 88, No. 17 ( 1991-09), p. 7477-7480
Abstract:
A theory is developed to predict marker retention and conditional retention or loss in radiation hybrids. Applied to multiple pairwise analysis of a human chromosome 21 data set, this theory fits much better than proposed alternatives and gives a physical map consistent with other evidence and robust with respect to errors to typing. Radiation hybrids have great promise to provide order and physical location at two levels of resolution, spanning the techniques of linkage and restriction fragments and not limited to polymorphic loci.
Type of Medium:
Online Resource
ISSN:
0027-8424
,
1091-6490
DOI:
10.1073/pnas.88.17.7477
Language:
English
Publisher:
Proceedings of the National Academy of Sciences
Publication Date:
1991
detail.hit.zdb_id:
209104-5
detail.hit.zdb_id:
1461794-8
SSG:
11
SSG:
12
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