In:
Paediatric and Perinatal Epidemiology, Wiley, Vol. 27, No. 4 ( 2013-07), p. 415-425
Abstract:
The M aternal‐ I nfant R esearch on E nvironmental C hemicals ( MIREC ) S tudy was established to obtain C anadian biomonitoring data for pregnant women and their infants, and to examine potential adverse health effects of prenatal exposure to priority environmental chemicals on pregnancy and infant health. Methods Women were recruited during the first trimester from 10 sites across C anada and were followed through delivery. Questionnaires were administered during pregnancy and post‐delivery to collect information on demographics, occupation, life style, medical history, environmental exposures and diet. Information on the pregnancy and the infant was abstracted from medical charts. Maternal blood, urine, hair and breast milk, as well as cord blood and infant meconium, were collected and analysed for an extensive list of environmental biomarkers and nutrients. Additional biospecimens were stored in the study's B iobank. The MIREC R esearch P latform encompasses the main cohort study, the B iobank and follow‐up studies. Results Of the 8716 women approached at early prenatal clinics, 5108 were eligible and 2001 agreed to participate (39%). MIREC participants tended to smoke less (5.9% vs. 10.5%), be older (mean 32.2 vs. 29.4 years) and have a higher education (62.3% vs. 35.1% with a university degree) than women giving birth in C anada. Conclusions The MIREC S tudy, while smaller in number of participants than several of the international cohort studies, has one of the most comprehensive datasets on prenatal exposure to multiple environmental chemicals. The biomonitoring data and biological specimen bank will make this research platform a significant resource for examining potential adverse health effects of prenatal exposure to environmental chemicals.
Type of Medium:
Online Resource
ISSN:
0269-5022
,
1365-3016
DOI:
10.1111/ppe.2013.27.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
639089-4
detail.hit.zdb_id:
2008566-7
Permalink
