In:
Journal of Heterocyclic Chemistry, Wiley, Vol. 52, No. 2 ( 2015-03), p. 336-345
Abstract:
The reaction of 3(5)‐amino‐5(3)‐hydrazinopyrazole, a bifunctional compound, with 3‐oxo‐3‐phenylpropanenitrile and two of its p ‐substituted derivatives affords 2,5‐diaryl‐7‐aminopyrazolo[1,5‐ a ]pyrimidines. A mechanism for this unexpected reaction involving the formation of hydrazine is proposed. The position of the aryl substituents on the bicyclic ring has been established by the combined use of NMR and DFT calculations. Moreover, the chemical shifts have been calculated, and some general rules have been withdrawn.
Type of Medium:
Online Resource
ISSN:
0022-152X
,
1943-5193
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2042274-X
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