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  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2014
    In:  Applied Psycholinguistics Vol. 35, No. 6 ( 2014-11), p. 1235-1257
    In: Applied Psycholinguistics, Cambridge University Press (CUP), Vol. 35, No. 6 ( 2014-11), p. 1235-1257
    Abstract: We developed the Hong Kong Specific Learning Difficulties Behavior Checklist for Junior Secondary School Students (BCL-JS) for teachers to rate the frequency of 52 reading-related behavioral characteristics of Chinese secondary school students. An item factor analysis based on ratings on 947 students yielded seven distinct dimensions. In a separate sample of 90 students, the seven constructs of the BCL-JS significantly correlated with students’ performances on most literacy and reading-related cognitive measures, and differentiated adolescents with or without dyslexia. Discriminant analysis showed that the BCL-JS had a high rate of correct classification (82.2%). These findings support that the BCL-JS is a reliable screening tool for Chinese junior secondary school students at risk for dyslexia.
    Type of Medium: Online Resource
    ISSN: 0142-7164 , 1469-1817
    RVK:
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    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2014
    detail.hit.zdb_id: 1499968-7
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  • 2
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2023
    In:  Journal of Fluid Mechanics Vol. 959 ( 2023-03-25)
    In: Journal of Fluid Mechanics, Cambridge University Press (CUP), Vol. 959 ( 2023-03-25)
    Abstract: In the fully rough regime, proposed models predict a scaling for a roughness heat-transfer coefficient, e.g. the roughness Stanton number ${St}_k \sim (k^+)^{-p} {Pr}^{-m}$ where the exponent values $p$ and $m$ are model dependent, giving diverse predictions. Here, $k^+$ is the roughness Reynolds number and ${Pr}$ is the Prandtl number. To clarify this ambiguity, we conduct direct numerical simulations of forced convection over a three-dimensional sinusoidal surface spanning $k^+ = 5.5$ – $111$ for Prandtl numbers ${Pr} = 0.5$ , 1.0 and 2.0. These unprecedented parameter ranges are reached by employing minimal channels, which resolve the roughness sublayer at an affordable cost. We focus on the fully rough phenomenologies, which fall into two groups: $p=1/2$ (Owen & Thomson, J. Fluid Mech. , vol. 15, issue 3, 1963, pp. 321–334; Yaglom & Kader, J. Fluid Mech. , vol. 62, issue 3, 1974, pp. 601–623) and $p=1/4$ (Brutsaert, Water Resour. Res. , vol. 11, issue 4, 1975 b , pp. 543–550). Although we find the mean heat transfer favours the $p=1/4$ scaling, the Prandtl–Blasius boundary-layer ideas associated with the Reynolds–Chilton–Colburn analogy that underpin the $p=1/2$ can remain an apt description of the flow locally in regions exposed to high shear. Sheltered regions, meanwhile, violate this behaviour and are instead dominated by reversed flow, where no clear correlation between heat and momentum transfer is evident. The overall picture of fully rough heat transfer is then not encapsulated by one singular mechanism or phenomenology, but rather an ensemble of different behaviours locally. The implications of the approach to a Reynolds-analogy-like behaviour locally on bulk measures of the Nusselt and Stanton numbers are also examined, with evidence pointing to the onset of a regime transition at even-higher Reynolds numbers.
    Type of Medium: Online Resource
    ISSN: 0022-1120 , 1469-7645
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 1472346-3
    detail.hit.zdb_id: 218334-1
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  Cambridge Quarterly of Healthcare Ethics Vol. 9, No. 3 ( 2000-07), p. 353-364
    In: Cambridge Quarterly of Healthcare Ethics, Cambridge University Press (CUP), Vol. 9, No. 3 ( 2000-07), p. 353-364
    Abstract: Cosmetic surgery is a fast-growing medical practice. In 1997 surgeons in the United States performed the four most common cosmetic procedures—liposuction, breast augmentation, eyelid surgery, and facelift—443,728 times, an increase of 150% over the comparable total for 1992. Estimated total expenditures for cosmetic surgery range from $1 to $2 billion. As managed care cuts into physicians' income and autonomy, cosmetic surgery, which is not covered by health insurance, offers a financially attractive medical specialty.
    Type of Medium: Online Resource
    ISSN: 0963-1801 , 1469-2147
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 1499985-7
    SSG: 0
    SSG: 5,1
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  • 4
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2017
    In:  Applied Psycholinguistics Vol. 38, No. 1 ( 2017-01), p. 211-231
    In: Applied Psycholinguistics, Cambridge University Press (CUP), Vol. 38, No. 1 ( 2017-01), p. 211-231
    Abstract: This study examined the role of transcription skills (including spelling and handwriting fluency) and oral language skills in Chinese writing development among upper elementary grade students in Hong Kong. Measures assessing verbal working memory, spelling, handwriting fluency, oral narrative skills, syntactic skills, and written composition were administered to 97 students in Grade 4 ( n = 47) and Grade 6 ( n = 50). Hierarchical multiple regression results showed that spelling and oral narrative skills were unique predictors of Chinese writing performance. The significant interaction effect of grade and spelling showed that transcription skills played a more important role in Chinese writing performance among sixth graders than among fourth graders. Together, the present results provide important support for the “simple view of writing” model and underscore the importance of transcription skills and oral narrative skills in children's writing development in Chinese.
    Type of Medium: Online Resource
    ISSN: 0142-7164 , 1469-1817
    RVK:
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    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2017
    detail.hit.zdb_id: 1499968-7
    SSG: 5,2
    SSG: 7,11
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  • 5
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2013
    In:  Applied Psycholinguistics Vol. 34, No. 6 ( 2013-11), p. 1245-1277
    In: Applied Psycholinguistics, Cambridge University Press (CUP), Vol. 34, No. 6 ( 2013-11), p. 1245-1277
    Abstract: The longitudinal predictive power of four important reading-related skills (phonological skills, rapid naming, orthographic skills, and morphological awareness) to Chinese word reading and writing to dictation (i.e., spelling) was examined in a 3-year longitudinal study among 251 Chinese elementary students. Rapid naming, orthographic skills, and morphological awareness assessed in Grade 1 were significant longitudinal predictors of Chinese word reading in Grades 1 to 4. As for word spelling, rapid naming was the only significant predictor across grades. Morphological awareness was a robust predictor of word spelling in Grade 1 only. Phonological skills and orthographic skills significantly predicted word spelling in Grades 2 and 4. After controlling for autoregressive effects, morphological awareness and orthographic skills were the significant longitudinal predictors of Chinese word reading and word spelling, respectively. These findings reflected the impacts of the Chinese orthography on children's reading and spelling development.
    Type of Medium: Online Resource
    ISSN: 0142-7164 , 1469-1817
    RVK:
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2013
    detail.hit.zdb_id: 1499968-7
    SSG: 5,2
    SSG: 7,11
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  • 6
    In: Journal of Clinical and Translational Science, Cambridge University Press (CUP), Vol. 7, No. 1 ( 2023)
    Abstract: Designing and conducting clinical trials is challenging for some institutions and researchers due to associated time and personnel requirements. We conducted recruitment, screening, informed consent, study product distribution, and data collection remotely. Our objective is to describe how to conduct a randomized clinical trial using remote and automated methods. Methods: A randomized clinical trial in healthcare workers is used as a model. A random group of workers were invited to participate in the study through email. Following an automated process, interested individuals scheduled consent/screening interviews. Enrollees received study product by mail and surveys via email. Adherence to study product and safety were monitored with survey data review and via real-time safety alerts to study staff. Results: A staff of 10 remotely screened 406 subjects and enrolled 299 over a 3-month period. Adherence to study product was 87%, and survey data completeness was 98.5% over 9 months. Participants and study staff scored the System Usability Scale 93.8% and 90%, respectively. The automated and remote methods allowed the study maintenance period to be managed by a small study team of two members, while safety monitoring was conducted by three to four team members. Conception of the trial to study completion was 21 months. Conclusions: The remote and automated methods produced efficient subject recruitment with excellent study product adherence and data completeness. These methods can improve efficiency without sacrificing safety or quality. We share our XML file for researchers to use as a template for learning purposes or designing their own clinical trials.
    Type of Medium: Online Resource
    ISSN: 2059-8661
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2898186-8
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  • 7
    In: Journal of Clinical and Translational Science, Cambridge University Press (CUP), Vol. 7, No. s1 ( 2023-04), p. 99-99
    Abstract: OBJECTIVES/GOALS: Multiple Organ Failure, often precipitated by Acute Lung Injury, is a life-threatening condition that causes death in military and civilian life. Furthermore, Acute Kidney Injury is very common, increasing morbidity and mortality rates. Therefore, understanding the molecular difference between survivors and non-survivors is urgently needed. METHODS/STUDY POPULATION: A 24-hour unilateral pulmonary contusion porcine model (pneumonectomy) of trauma-induced Multiple Organ Failure (MOF) model (n=17) and separate 48-hour polytrauma injury of bilateral pulmonary contusion, traumatic brain injury, and hemorrhage (polytrauma) MOF model (n=26) was developed at Dr. Batchinsky's AREVA laboratory. Serum was assayed at baseline and 3h or 6h post-trauma for amino acid metabolites using the Zip-Chip platform for mass spectrometry. The IDO1 enzyme activity assay kit (ab235936) was used to measure IDO1 enzyme activity in the tissue. Mass Spectrometry Imaging (MSI) was employed to frozen kidney tissues. Tissues were sectioned to 10- micron thickness. For MSI, the DAN matrix was utilized, and MALDI-MSI images were processed and obtained from METASPACE and SCILS software. RESULTS/ANTICIPATED RESULTS: In the pneumonectomy model, 10 survived, 7 died, and in the polytrauma group, 13 survived, and 13 died. In the pneumonectomy model, there was a significant increase in the serum kynurenine/tryptophan (KYN/TRP) ratio in the non-survivors 3h post-injury. A similar pattern was found in the validation group, which showed a significant increase in the KYN/TRP ratio at 6h post-trauma in non-survivors from the polytrauma model. There was a significant increase in IDO1 enzyme activity in non-survivor kidney tissues and a downregulation of tryptophan (TRP) metabolite in the kidney section in the non-survivor group post-trauma. DISCUSSION/SIGNIFICANCE: An increase in the KYN/TRP ratio post-trauma identified the pigs that suffered early mortality. A decrease in TRP metabolite and an increase in IDO1 enzyme activity in the kidney could contribute to an increase in KYN in the non-survivors. As a result, focusing on therapeutics targeting the KYN/TRP to reduce the incidence and severity of MOF is warranted.
    Type of Medium: Online Resource
    ISSN: 2059-8661
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2898186-8
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  • 8
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2006
    In:  Journal of Child Language Vol. 33, No. 1 ( 2006-02), p. 145-161
    In: Journal of Child Language, Cambridge University Press (CUP), Vol. 33, No. 1 ( 2006-02), p. 145-161
    Abstract: The present study examined word learning difficulties in Chinese dyslexic children, readers of a nonalphabetic script. A total of 105 Hong Kong Chinese children were recruited and divided into three groups: Dyslexic (mean age 8;8), CA control (mean age 8;9), and RL control (mean age 6;11). They were given a word learning task and a familiar word writing task. It was found that the Dyslexic group performed less well than the RL group in learning irregular words over trials but not the regular ones. Error analyses showed that the Dyslexic group made more orthographic and word association errors but less intra-wordlist interference errors than the RL control group. The Dyslexic group also performed significantly less well than both control groups in writing familiar words (e.g. their own name). These findings suggest that Chinese dyslexic children have difficulty learning new words, especially irregular ones, and retaining overlearned words in long-term memory. We conclude that Chinese dyslexic children have a specific impairment in word learning like their alphabetic counterparts.
    Type of Medium: Online Resource
    ISSN: 0305-0009 , 1469-7602
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    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2006
    detail.hit.zdb_id: 1466489-6
    SSG: 5,2
    SSG: 7,11
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