In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 4 ( 2022-4-19), p. e0267111-
Kurzfassung:
Schools are primary venues of influenza amplification with secondary spread to communities. We assessed K-12 student absenteeism monitoring as a means for early detection of influenza activity in the community. Materials and methods Between September 2014 and March 2020, we conducted a prospective observational study of all-cause (a-TOT), illness-associated (a-I), and influenza-like illness–associated (a-ILI) absenteeism within the Oregon School District (OSD), Dane County, Wisconsin. Absenteeism was reported through the electronic student information system. Students were visited at home where pharyngeal specimens were collected for influenza RT-PCR testing. Surveillance of medically-attended laboratory-confirmed influenza (MAI) occurred in five primary care clinics in and adjoining the OSD. Poisson general additive log linear regression models of daily counts of absenteeism and MAI were compared using correlation analysis. Findings Influenza was detected in 723 of 2,378 visited students, and in 1,327 of 4,903 MAI patients. Over six influenza seasons, a-ILI was significantly correlated with MAI in the community (r = 0.57; 95% CI: 0.53–0.63) with a one-day lead time and a-I was significantly correlated with MAI in the community (r = 0.49; 0.44–0.54) with a 10-day lead time, while a-TOT performed poorly (r = 0.27; 0.21–0.33), following MAI by six days. Discussion Surveillance using cause-specific absenteeism was feasible and performed well over a study period marked by diverse presentations of seasonal influenza. Monitoring a-I and a-ILI can provide early warning of seasonal influenza in time for community mitigation efforts.
Materialart:
Online-Ressource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0267111
DOI:
10.1371/journal.pone.0267111.g001
DOI:
10.1371/journal.pone.0267111.g002
DOI:
10.1371/journal.pone.0267111.g003
DOI:
10.1371/journal.pone.0267111.g004
DOI:
10.1371/journal.pone.0267111.g005
DOI:
10.1371/journal.pone.0267111.t001
DOI:
10.1371/journal.pone.0267111.t002
DOI:
10.1371/journal.pone.0267111.t003
DOI:
10.1371/journal.pone.0267111.t004
DOI:
10.1371/journal.pone.0267111.t005
DOI:
10.1371/journal.pone.0267111.s001
DOI:
10.1371/journal.pone.0267111.s002
DOI:
10.1371/journal.pone.0267111.r001
DOI:
10.1371/journal.pone.0267111.r002
DOI:
10.1371/journal.pone.0267111.r003
DOI:
10.1371/journal.pone.0267111.r004
DOI:
10.1371/journal.pone.0267111.r005
DOI:
10.1371/journal.pone.0267111.r006
Sprache:
Englisch
Verlag:
Public Library of Science (PLoS)
Publikationsdatum:
2022
ZDB Id:
2267670-3
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