In:
Ophthalmologica, S. Karger AG, Vol. 237, No. 3 ( 2017), p. 128-138
Abstract:
〈 b 〉 〈 i 〉 Purpose: 〈 /i 〉 〈 /b 〉 The aim of this study was to determine the correlation between the duration of myopic choroidal neovascularization (CNV) and treatment outcome after anti-vascular endothelial growth factor (VEGF) injections. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 We performed a retrospective review of treatment-naïve myopic CNV patients who were treated with anti-VEGF and followed for at least 24 months to identify factors predicting final outcome and recurrence. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Among 106 eyes, a shorter duration of CNV was a significant predictor of a better final best-corrected visual acuity, even after controlling for other factors ( 〈 i 〉 p 〈 /i 〉 = 0.042). When divided into 3 groups according to CNV duration before treatment ( 〈 2, 2-8, and 8-24 weeks), the recurrence rate (19, 25, and 52%, respectively; 〈 i 〉 p 〈 /i 〉 = 0.006) and number of injections (3.5, 4.0, and 5.5, respectively; 〈 i 〉 p = 〈 /i 〉 0.021) were significantly lower in eyes with a shorter duration of CNV. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Early anti-VEGF treatment of myopic CNV decreased the recurrence rate and number of injections and improved visual outcome.
Type of Medium:
Online Resource
ISSN:
0030-3755
,
1423-0267
Language:
English
Publisher:
S. Karger AG
Publication Date:
2017
detail.hit.zdb_id:
1483531-9
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