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  • Ching, Lee Phong  (2)
  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Journal of the Royal College of Physicians of Edinburgh Vol. 51, No. 2 ( 2021-06), p. 207-207
    In: Journal of the Royal College of Physicians of Edinburgh, SAGE Publications, Vol. 51, No. 2 ( 2021-06), p. 207-207
    Abstract: Rhabdomyolysis is a clinical syndrome characterised by the destruction of skeletal muscle with subsequent leakage of intracellular muscle contents into the systemic circulation. It is commonly caused by trauma, strenuous physical activities, medications, illicit drug use, toxins, infections and electrolyte abnormalities. It can manifest as myalgia, muscle weakness, or myoglobinuria with or without acute kidney injury. Severe hypokalaemia leading to rhabdomyolysis is a rare initial presentation of primary aldosteronism, with limited case reports in existing medical literature. Here, we report a case of primary hyperaldosteronism presenting with rhabdomyolysis due to profound hypokalaemia.
    Type of Medium: Online Resource
    ISSN: 1478-2715 , 2042-8189
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2252067-3
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  • 2
    In: DEN Open, Wiley, Vol. 3, No. 1 ( 2023-04)
    Abstract: Endoscopic sleeve gastroplasty (ESG) is an effective treatment for obesity. Recently, a novel single‐channel endoscopic suturing device has been made available to overcome the need for a double‐channel endoscope. However, there is limited evidence evaluating its utility for ESG. In this multicenter study, we aim to assess the efficacy and safety of the single‐channel suturing device for ESG. Methods We reviewed the records of 18 patients who underwent ESG using the novel device at the Singapore General Hospital, Singapore, and Siriraj Hospital, Bangkok, between 2020–2021. We adopted a “U” suture pattern. Our primary outcome was to assess technical feasibility and safety. The secondary outcome was to determine the percentage of total body weight loss at 1 year. Results The mean ± SD age and body mass index were 42 ± 8.5 years and 34.9 ± 4.4 kg/m 2 , respectively. The majority were female (61%). ESG was technically successful in 94% ( n  = 17) of patients. Device dislodgement occurred in one patient. We used an average of five sutures (range, 4–8), and the mean ± SD procedure time was 96.5 ± 43.8 min. No complications occurred. The mean ± SD length of stay was 2.3 ± 1.5 days. The mean ± SD percentage of total body weight loss at 6 and 12 months were 16 ± 5.2% and 13.1 ± 5.8%, respectively. We found that  〉 5%,  〉 10%, and  〉 15% total body weight loss was observed in 83.3%, 72.2%, and 56%, respectively. Conclusion ESG using the single‐channel endoscopic suturing system is safe and effective for inducing weight loss at 1 year in patients with obesity.
    Type of Medium: Online Resource
    ISSN: 2692-4609 , 2692-4609
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 3045363-X
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