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  • Chen, Yucheng  (322)
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  • 1
    Online Resource
    Online Resource
    Diverse Right Ventricular Remodeling Evaluated by MRI and Prognosis in Eisenmenger Syndrome With Different Shunt Locations
    Wiley ; 2022
    In:  Journal of Magnetic Resonance Imaging Vol. 55, No. 5 ( 2022-05), p. 1478-1488
    Details
    In: Journal of Magnetic Resonance Imaging, Wiley, Vol. 55, No. 5 ( 2022-05), p. 1478-1488
    Abstract: Congenital shunt location is related to Eisenmenger syndrome (ES) survival. Moreover, right ventricular (RV) remodeling is associated with poor survival in pulmonary hypertension. Purpose To investigate RV remodeling using comprehensive magnetic resonance imaging (MRI) techniques and identify its relationship with prognosis in ES subgroups classified by shunt location. Study Type Prospective observational study. Population Fifty‐four adults with ES (16 with pre‐tricuspid shunt and 38 with post‐tricuspid shunt). Field Strength/Sequence 3. 0 T /cine MRI with balanced steady‐state free precession sequence, late gadolinium enhancement with inversion recovery segmented gradient echo sequence and phase‐sensitive reconstruction, and T1 mapping with modified Look‐Locker inversion recovery sequence. Assessment Demographics, clinical characteristics, hemodynamics, RV remodeling features (morphology, systolic function, RV–pulmonary artery (PA) coupling and myocardial fibrosis), and prognosis were compared between ES subgroups. The adverse endpoint was all‐cause mortality or readmission for heart failure. Statistical Tests The independent samples t ‐test, Fisher's exact test or Chi‐squared test, and the Kaplan–Meier method were used. P   〈  0.05 was considered significant. Results Compared to patients with post‐tricuspid shunt, patients with pre‐tricuspid shunt were significantly older and had higher N‐terminal pro‐B‐type natriuretic peptide concentrations and poorer exercise tolerance. Pre‐tricuspid shunt showed significantly larger RV dimensions (end‐diastolic volume index: 185.81 ± 37.49 vs. 98.20 ± 36.26 mL/m 2 ), worse RV ejection fraction (23.54% ± 12.35% vs. 40.82% ± 10.77%), and RV–PA decoupling (0.35 ± 0.31 vs. 0.72 ± 0.29). Biventricular myocardial fibrosis was significantly more severe in pre‐tricuspid shunt than post‐tricuspid shunt (extracellular volume, left ventricle: 35.85% ± 2.58% vs. 29.10% ± 5.20%; RV free wall: 30.93% ± 5.65% vs. 26.75% ± 5.15%). In addition, pre‐tricuspid shunt demonstrated a significantly increased risk of adverse endpoint (hazard ratio: 2.938, 95% confidence interval: 1.204–7.172). Data Conclusion ES with pre‐tricuspid shunt might be a unique subtype with worse clinically decompensated RV remodeling and poor prognosis. Level of Evidence : 2 Technical Efficacy Stage : 5
    Type of Medium: Online Resource
    ISSN: 1053-1807 , 1522-2586
    URL: Issue
    URL: Article
    DOI: 10.1002/jmri.v55.5
    DOI: 10.1002/jmri.27791
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 1497154-9
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  • 2
    Online Resource
    Online Resource
    Corrected MRI Pulmonary Transit Time for Identification of Combined Precapillary and Postcapillary Pulmonary Hypertension in Patients With Left Heart Disease
    Wiley ; 2023
    In:  Journal of Magnetic Resonance Imaging Vol. 57, No. 5 ( 2023-05), p. 1518-1528
    Details
    In: Journal of Magnetic Resonance Imaging, Wiley, Vol. 57, No. 5 ( 2023-05), p. 1518-1528
    Abstract: The identification of combined precapillary and postcapillary pulmonary hypertension (CpcPH) in patients with pulmonary hypertension (PH) due to left heart disease (LHD) can influence therapy and outcome and is currently based on invasively determined hemodynamic parameters. Purpose To investigate the diagnostic value of MRI‐derived corrected pulmonary transit time (PTTc) in PH‐LHD sub‐grouped according to hemodynamic phenotypes. Study Type Prospective observational study. Population A total of 60 patients with PH‐LHD (18 with isolated postcapillary PH [IpcPH] and 42 with CpcPH), and 33 healthy subjects. Field Strength/Sequence A 3.0 T/balanced steady‐state free precession cine and gradient echo‐train echo planar pulse first‐pass perfusion. Assessment In patients, right heart catheterization (RHC) and MRI were performed within 30 days. Pulmonary vascular resistance (PVR) was used as the diagnostic “reference standard.” The PTTc was calculated as the time interval between the peaks of the biventricular signal‐intensity/time curve and corrected for heart rate. PTTc was compared between patient groups and healthy subjects and its relationship to PVR assessed. The diagnostic accuracy of PTTc for distinguishing IpcPH and CpcPH was determined. Statistical Tests Student's t ‐test, Mann–Whitney U‐test, linear and logistic regression analysis, and receiver‐operating characteristic curves. Significance level: P   〈  0.05. Results PTTc was significantly prolonged in CpcPH compared with IpcPH and normal controls (17.28 ± 7.67 vs. 8.82 ± 2.55 vs. 6.86 ± 2.11 seconds), and in IpcPH compared with normal controls (8.82 ± 2.55 vs. 6.86 ± 2.11 seconds). Prolonged PTTc was significantly associated with increased PVR. Furthermore, PTTc was a significantly independent predictor of CpcPH (odds ratio: 1.395, 95% confidence interval: 1.071–1.816). The area under curve was 0.852 at a cut‐off value of 11.61 seconds for PTTc to distinguish between CpcPH and IpcPH (sensitivity 71.43% and specificity 94.12%). Data Conclusion PTTc may be used to identify CpcPH. Our findings have potential to improve selection for invasive RHC for PH‐LHD patients. Evidence Level 3 Technical Efficacy Stage 2
    Type of Medium: Online Resource
    ISSN: 1053-1807 , 1522-2586
    URL: Issue
    URL: Article
    DOI: 10.1002/jmri.v57.5
    DOI: 10.1002/jmri.28386
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1497154-9
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  • 3
    Online Resource
    Online Resource
    Detection and evaluation of myocardial fibrosis in Eisenmenger syndrome using cardiovascular magnetic resonance late gadolinium enhancement and T1 mapping
    Elsevier BV ; 2022
    In:  Journal of Cardiovascular Magnetic Resonance Vol. 24, No. 1 ( 2022-01), p. 60-
    Details
    In: Journal of Cardiovascular Magnetic Resonance, Elsevier BV, Vol. 24, No. 1 ( 2022-01), p. 60-
    Type of Medium: Online Resource
    ISSN: 1097-6647
    URL: Article
    DOI: 10.1186/s12968-022-00880-2
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 2578881-4
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  • 4
    Online Resource
    Online Resource
    Prognostic Value of Hepatic Native T1 and Extracellular Volume Fraction in Patients with Pulmonary Arterial Hypertension
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Journal of the American Heart Association Vol. 11, No. 22 ( 2022-11-15)
    Details
    In: Journal of the American Heart Association, Ovid Technologies (Wolters Kluwer Health), Vol. 11, No. 22 ( 2022-11-15)
    Abstract: Right heart failure may lead to impaired liver perfusion and venous congestion, resulting in different extents of liver fibrosis. However, whether hepatic tissue deterioration determined by native T1 mapping and extracellular volume fraction using cardiac magnetic resonance imaging is associated with poor outcomes in patients with pulmonary arterial hypertension remains unclear. Methods and Results A total of 131 participants with pulmonary arterial hypertension (mean age, 36±13 years) and 64 healthy controls (mean age, 44±18) between October 2013 and December 2019 were prospectively enrolled. Hepatic native T1 and extracellular volume fraction values were measured using modified Look–Locker inversion recovery T1 mapping sequences. The primary end point was all‐cause mortality; the secondary end point was all‐cause mortality and repeat hospitalization attributable to heart failure. Cox regression models and Kaplan–Meier survival analysis were used to identify the association between variables and clinical outcome. During a median follow‐up of 34.5 months (interquartile range: 25.3–50.8), hepatic native T1 (hazard ratio per 30‐ms increase, 1.22 [95% CI, 1.07–1.39]; P =0.003) and extracellular volume fraction (hazard ratio per 3% increase, 1.18 [95% CI, 1.04–1.34]; P =0.010) values were associated with a higher risk of death. In the multivariate Cox model, hepatic native T1 value (hazard ratio per 30‐ms increase, 1.15 [95% CI, 1.04–1.27]; P =0.009) remained as an independent prognostic factor for the secondary end point. Conclusions Hepatic T1 mapping values were predictors of adverse cardiovascular events in participants with pulmonary arterial hypertension and could be novel imaging biomarkers for poor prognosis recognition.
    Type of Medium: Online Resource
    ISSN: 2047-9980
    URL: Article
    DOI: 10.1161/JAHA.122.026254
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2653953-6
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  • 5
    Online Resource
    Online Resource
    A novel blood pressure monitoring technique by smart HUAWEI WATCH: A validation study according to the ANSI/AAMI/ISO 81060-2:2018 guidelines
    Frontiers Media SA ; 2022
    In:  Frontiers in Cardiovascular Medicine Vol. 9 ( 2022-10-11)
    Details
    In: Frontiers in Cardiovascular Medicine, Frontiers Media SA, Vol. 9 ( 2022-10-11)
    Abstract: Given the rapid innovation of wearable technology, additional physical indicators can be detected, and blood pressure (BP) has become the focus of many emerging medical-device manufacturers. This study aimed to validate the accuracy of the newly developed HUAWEI WATCH in BP monitoring, according to the American National Standards Institute/Association for the Advancement of Medical Instrumentation/International Organization for Standardization (ANSI/AAMI/ISO 81060-2:2018) guidelines. Materials and methods The same arm sequential BP measurement was applied. One validation included four reference BP measurements taken simultaneously by two independent observers using a mercury sphygmomanometer, alternating with three test-watch measurements. Each test-watch measurement was compared against the average of the previous and subsequent reference BP readings. Two criteria were required for validation: (1) a mean BP difference of 5 mm Hg or less, with a standard deviation (SD) of 8 mm Hg or less for systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the 255 pairs of measurements, and (2) an SD for the of 85 averaged BP differences within the threshold defined by the mean test-reference BP difference listed in the ANSI/AAMI/ISO 81060-2:2018 guidelines. Results The mean age of the 85 participants was 48 ± 18 years (range: 21–85), and 53 (62.4%) were male. The mean differences between the test and reference BPs were -0.25 ± 5.62 mm Hg and -1.33 ± 6.81 mm Hg for SBP and DBP, respectively (according to Criterion 1). The mean differences between the test BPs and reference BPs were -0.25 ± 5.00 mm Hg and -1.33 ± 6.31 mm Hg for SBP and DBP, respectively, according to Criterion 2. Conclusion Blood pressure measurement using the HUAWEI WATCH showed excellent consistency with reference BPs, and fulfilled both validation criteria of the guidelines, show its promise as a wearable device for BP self-monitoring.
    Type of Medium: Online Resource
    ISSN: 2297-055X
    URL: Article
    DOI: 10.3389/fcvm.2022.923655
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2781496-8
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  • 6
    Online Resource
    Online Resource
    P‐223L: Late‐News Poster : New Head‐Up Display System with Ultrahigh Transmittance Using LCs with Negative Dielectric Anisotropy and RGBW Design
    Wiley ; 2017
    In:  SID Symposium Digest of Technical Papers Vol. 48, No. 1 ( 2017-05), p. 1397-1399
    Details
    In: SID Symposium Digest of Technical Papers, Wiley, Vol. 48, No. 1 ( 2017-05), p. 1397-1399
    Abstract: We have developed a novel head‐up display (HUD) system with 13.7% transmittance by combining RGBW design, LCs with negative dielectric anisotropy and local dimming backlight. With high transmittance, high contrast ratio and low power, the newly designed HUD system could be more suitable for automotive vehicles.
    Type of Medium: Online Resource
    ISSN: 0097-966X , 2168-0159
    URL: Issue
    URL: Article
    DOI: 10.1002/sdtp.2017.48.issue-1
    DOI: 10.1002/sdtp.11914
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2526337-7
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  • 7
    Online Resource
    Online Resource
    Dilation Eustachian Tuboplasty with Visual Eustachian Tube Endoscope and Supporting Balloon
    Cambridge University Press (CUP) ; 2023
    In:  The Journal of Laryngology & Otology
    Details
    In: The Journal of Laryngology & Otology, Cambridge University Press (CUP)
    Type of Medium: Online Resource
    ISSN: 0022-2151 , 1748-5460
    URL: Article
    DOI: 10.1017/S0022215123001202
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2013209-8
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  • 8
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    Probabilistic linguistic fuzzy cognitive maps: applications to the critical factors affecting the health of rural older adults
    Springer Science and Business Media LLC ; 2022
    In:  BMC Medical Informatics and Decision Making Vol. 22, No. 1 ( 2022-11-17)
    Details
    In: BMC Medical Informatics and Decision Making, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-11-17)
    Abstract: Achieving healthy ageing has become the only way for China to alleviate the pressure of ageing, especially in rural areas. However, the factors affecting the health of rural older adults are numerous and complex. It is important to identify the critical factors that affecting the health of older adults in rural areas and provide decision-making support for targeted health interventions. Methods To overcome some limitations of existing works, an extended probabilistic linguistic fuzzy cognitive map model is proposed in this paper as a useful tool for modeling the cause-effect relationship between factors. The proposed model integrates the advantages of probabilistic linguistic term sets and fuzzy cognitive maps. In the end, to rank and identify the critical factors affecting the health, a novel similarity measure based on Euclidean distance and Z-mapping function is proposed. Results The proposed model can effectively deal with the uncertainty of experts and reflect different opinions of groups well. In terms of representing uncertainty and ambiguity, the proposed method outperforms other models in modeling complex systems. In the real-world case analysis, we find that education is the most important factor affecting the health of rural older adults, followed by previous occupational experiences , psychology , and physical exercise , among other things. Intergenerational relationship has become another important factor affecting the health of rural older adults in China as the development of Chinese society. Conclusions From a macro perspective, social economic status , living environment , lifestyle , and health management , are the variables that have the greatest impact on the health of rural older adults. As a result, providing more precise health interventions with the characteristics of factors influencing health is a crucial guarantee for preserving and improving the health of rural older adults in China.
    Type of Medium: Online Resource
    ISSN: 1472-6947
    URL: Article
    DOI: 10.1186/s12911-022-02028-9
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2046490-3
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  • 9
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    Left ventricular underfilling in PAH: A potential indicator for adaptive‐to‐maladaptive transition
    Wiley ; 2023
    In:  Pulmonary Circulation Vol. 13, No. 4 ( 2023-10)
    Details
    In: Pulmonary Circulation, Wiley, Vol. 13, No. 4 ( 2023-10)
    Abstract: Pulmonary arterial hypertension (PAH) still remains a life‐threatening disorder with poor prognosis. The right ventricle (RV) adapts to the increased afterload by a series of prognostically significant morphological and functional changes, the adaptive nature should also be understood in the context of ventricular interdependence. We hypothesized that left ventricle (LV) underfilling could serve as an important imaging marker for identifying maladaptive changes and predicting clinical outcomes in PAH patients. We prospectively enrolled patients with PAH who underwent both cardiac magnetic resonance and right heart catheterization between October 2013 and December 2020. Patients were categorized into four groups based on their LV and RV mass/volume ratio (M/V). LV M/V was stratified using the normal value (0.7 g/mL for males and 0.6 g/mL for females) to identify patients with LV underfilling (M/V ≥ normal value), while RV M/V was stratified based on the median value. The primary endpoint was all‐cause mortality, and the composite endpoints included all‐cause mortality and heart failure‐related readmissions. A total of 190 PAH patients (53 male, mean age 37 years) were included in this study. Patients with LV underfilling exhibited higher NT‐proBNP levels, increased RV mass, larger RV but smaller LV, lower right ventricular ejection fraction, and shorter 6‐min walking distance. Patients with LV underfilling had a 2.7‐fold higher risk of mortality than those without and LV M/V (hazard ratio [per 0.1 g/mL increase]: 1.271, 95% confidence interval: 1.082–1.494, p = 0.004) was also independent predictors of all‐cause mortality. Moreover, patients with low LV M/V had a better prognosis regardless of the level of RV M/V. Thus, LV underfilling is an independent predictor of adverse clinical outcomes in patients with PAH, and it could be an important imaging marker for identifying maladaptive changes in these patients.
    Type of Medium: Online Resource
    ISSN: 2045-8940 , 2045-8940
    URL: Issue
    URL: Article
    DOI: 10.1002/pul2.v13.4
    DOI: 10.1002/pul2.12309
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2638089-4
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  • 10
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    Prevalence and Prognostic Significance of Right Ventricular Dysfunction in Patients With Hypertrophic Cardiomyopathy
    Elsevier BV ; 2018
    In:  The American Journal of Cardiology Vol. 122, No. 11 ( 2018-12), p. 1932-1938
    Details
    In: The American Journal of Cardiology, Elsevier BV, Vol. 122, No. 11 ( 2018-12), p. 1932-1938
    Type of Medium: Online Resource
    ISSN: 0002-9149
    URL: Article
    DOI: 10.1016/j.amjcard.2018.08.043
    RVK:
    XA 18500
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2018
    detail.hit.zdb_id: 2019595-3
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