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  • Hindawi Limited  (2)
  • Chen, Xin-Zu  (2)
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  • Hindawi Limited  (2)
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  • 1
    In: Gastroenterology Research and Practice, Hindawi Limited, Vol. 2016 ( 2016), p. 1-10
    Abstract: Background . The impact of perioperative blood transfusion on the prognosis of gastric adenocarcinoma patients is still controversial. The aim of this study was to elucidate the impact of perioperative blood transfusion on postoperative complications and prognosis of patients who underwent gastrectomy for gastric adenocarcinoma with different levels of preoperative hemoglobin value (POHb). Method . From 2003 to 2011, 1199 patients who underwent curative gastrectomy were retrospectively enrolled and followed up to December 2014. Clinicopathological features and survival outcomes were compared between transfused and nontransfused patients. Results . In this study, transfused patients had more postoperative complications than nontransfused ones ( P = 0.002 ). In survival analysis, the difference was not significant between transfused and nontransfused patients with POHb between 70 and 100 g/L ( P = 0.191 ). However, in patients with POHb 〉 100 g/L, transfused patients had significantly worse prognosis ( P 〈 0.001 ), especially in TNM III stage patients ( P = 0.002 ). And intraoperative blood transfusion predicted poor prognosis ( P = 0.001 ). Conclusion . Perioperative blood transfusion might lead to poor survival in gastric adenocarcinoma patients with POHb 〉 100 g/L and transfused patients had more postoperative complications; thus it is better to refrain from unnecessary perioperative blood transfusion especially intraoperative transfusion.
    Type of Medium: Online Resource
    ISSN: 1687-6121 , 1687-630X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2435460-0
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  • 2
    In: Gastroenterology Research and Practice, Hindawi Limited, Vol. 2015 ( 2015), p. 1-7
    Abstract: Background . The studies on risk factors and metastatic rate of retropancreatic (number 13) lymph nodes in gastric adenocarcinoma were few and the results were still controversial. The aim of this study was to elucidate risk factors and prognostic significance of number 13 lymph nodes in gastric adenocarcinoma. Method . From January 2000 to December 2011, 114 patients who underwent gastrectomy with number 13 lymph nodes dissection were enrolled and followed up to January 2014. Patients were grouped according to whether number 13 lymph nodes were positive or negative. Results . The metastatic rate of number 13 lymph nodes was 22.8%. In multivariate analysis, pT stage ( P = 0.027 ), pN stage ( P = 0.005 ), and number 11p ( P = 0.015 ) lymph nodes were independent risk factors of positive number 13 lymph nodes. In all patients ( P 〈 0.001 ) and subpopulation with TNM III stage ( P = 0.007 ), positive number 13 lymph nodes had significantly worse prognosis than those of patients with negative number 13 LNs in Kaplan-Meier analysis. Conclusion . Number 13 lymph nodes had relatively high metastatic rate and led to poor prognosis. pT stage, pN stage, and number 11p lymph nodes were independent risk factors of positive number 13 lymph nodes.
    Type of Medium: Online Resource
    ISSN: 1687-6121 , 1687-630X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2015
    detail.hit.zdb_id: 2435460-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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