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  • Chen, Shih-Chang  (4)
  • Liaw, Yung-Po  (4)
  • 1
    Online Resource
    Online Resource
    A Simple Method for Increasing Levels of High-Density Lipoprotein Cholesterol: A Pilot Study of Combination Aerobic- and Resistance-Exercise Training
    Human Kinetics ; 2013
    In:  International Journal of Sport Nutrition and Exercise Metabolism Vol. 23, No. 3 ( 2013-06), p. 271-281
    Details
    In: International Journal of Sport Nutrition and Exercise Metabolism, Human Kinetics, Vol. 23, No. 3 ( 2013-06), p. 271-281
    Abstract: Evidence suggests that physical activity has a beneficial effect of elevated high-density lipoprotein cholesterol (HDL-C) on reducing coronary artery risk. However, previous studies show contrasting results for this association between different types of exercise training (i.e., aerobic, resistance, or combined aerobic and resistance training). The aim of this study was to determine which type of exercise training is more effective in increasing HDL-C levels. Forty obese men, age 18–29 yr, were randomized into 4 groups: an aerobic-training group ( n = 10), a resistance-training group ( n = 10), a combined-exercise-training group ( n = 10), and a control group ( n = 10). After a 12-wk exercise program, anthropometrics, blood biochemical variables, and physical-fitness components were compared with the data obtained at the baseline. Multiple-regression analysis was used to evaluate the association between different types of exercise training and changes in HDL-C while adjusting for potential confounders. The results showed that with the control group as the comparator, the effects of combined-exercise training (β = 4.17, p 〈 .0001), aerobic training (β = 3.65, p 〈 .0001), and resistance training (β = 2.10, p = .0001) were positively associated with increase in HDL-C after adjusting for potential confounders. Our findings suggested that a short-term exercise program can play an important role in increasing HDL-C levels; either aerobic or resistance training alone significantly increases the HDL-C levels, but the improvements are greatest with combined aerobic and resistance training.
    Type of Medium: Online Resource
    ISSN: 1526-484X , 1543-2742
    URL: Article
    DOI: 10.1123/ijsnem.23.3.271
    Language: Unknown
    Publisher: Human Kinetics
    Publication Date: 2013
    SSG: 31
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  • 2
    Online Resource
    Online Resource
    Geographic patterns of hepatocellular carcinoma mortality with exposure to iron in groundwater in Taiwanese population: An ecological study
    Springer Science and Business Media LLC ; 2013
    In:  BMC Public Health Vol. 13, No. 1 ( 2013-12)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2013-12)
    Abstract: Many studies have examined the risk factors for HCC (including hepatitis B virus, hepatitis C virus, aflatoxin, retinol, cigarette smoking, and alcohol consumption). However, data from previous studies on the association between iron exposure, land subsidence, and HCC mortality/incidence were limited, especially in Taiwanese population. We aimed to explore the geographical distribution of HCC mortality rates by township-specific data and to evaluate the association between HCC mortality, land subsidence, and iron levels in groundwater in Taiwan. Methods We conducted an ecological study and calculated the HCC age-standardized mortality/incidence rates according to death certificates issued in Taiwan from 1992 to 2001 and incidence data from 1995–1998. The land subsidence dataset before 2005 and iron concentrations in groundwater in 1989 are also involved in this study. Both geographical information systems and Pearson correlation coefficients were used to analyze the relationship between HCC mortality rates, land subsidence, and iron concentrations in groundwater. Results Township-specific HCC mortality rates are higher in southwestern coastal townships where serious land subsidence and higher township-specific concentrations of iron in groundwater are present. The Pearson correlation coefficients of iron concentrations in groundwater and ASRs of HCC were 0.286 ( P  = 0.004) in males and 0.192 ( P  = 0.058) in females for mortality data; the coefficients were 0.375 ( P   〈  0.001) in males and 0.210 ( P  = 0.038) in females for incidence data. Conclusions This study showed that HCC mortality is clustered in southwestern Taiwan and the association with the iron levels in groundwater in Taiwanese population warrant further investigation.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/1471-2458-13-352
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2041338-5
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  • 3
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    Online Resource
    Cell-type specificity of lung cancer associated with low-dose soil heavy metal contamination in Taiwan: An ecological study
    Springer Science and Business Media LLC ; 2013
    In:  BMC Public Health Vol. 13, No. 1 ( 2013-12)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2013-12)
    Abstract: Numerous studies have examined the association between heavy metal contamination (including arsenic [As], cadmium [Cd] , chromium [Cr], copper [Cu] , mercury [Hg], nickel [Ni] , lead [Pb], and zinc [Zn] ) and lung cancer. However, data from previous studies on pathological cell types are limited, particularly regarding exposure to low-dose soil heavy metal contamination. The purpose of this study was to explore the association between soil heavy metal contamination and lung cancer incidence by specific cell type in Taiwan. Methods We conducted an ecological study and calculated the annual averages of eight soil heavy metals (i.e., As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) by using data from the Taiwan Environmental Protection Administration from1982 to 1986. The age-standardized incidence rates of lung cancer according to two major pathological types (adenocarcinoma [AC] and squamous cell carcinoma [SCC] ) were obtained from the National Cancer Registry Program conducted in Taiwan from 2001 to 2005. A geographical information system was used to plot the maps of soil heavy metal concentration and lung cancer incidence rates. Poisson regression models were used to obtain the adjusted relative ratios (RR) and 95% confidence intervals (CI) for the lung cancer incidence associated with soil heavy metals. Results For males, the trend test for lung SCC incidence caused by exposure to Cr, Cu, Hg, Ni, and Zn showed a statistically significant dose–response relationship. However, for lung AC, only Cu and Ni had a significant dose–response relationship. As for females, those achieving a statistically significant dose–response relationship for the trend test were Cr (P = 0.02), Ni (P = 0.02), and Zn (P= 0.02) for lung SCC, and Cu (P 〈 0.01) and Zn (P = 0.02) for lung AC. Conclusion The current study suggests that a dose–response relationship exists between low-dose soil heavy metal concentration and lung cancer occurrence by specific cell-type; however, the relevant mechanism should be explored further.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/1471-2458-13-330
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2041338-5
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  • 4
    Online Resource
    Online Resource
    The association of anthropometry indices with gout in Taiwanese men
    Springer Science and Business Media LLC ; 2013
    In:  BMC Endocrine Disorders Vol. 13, No. 1 ( 2013-12)
    Details
    In: BMC Endocrine Disorders, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2013-12)
    Abstract: To examine the association of anthropometry indices with gout and to compare the performance of indices to predict gout in Taiwanese men. Methods There were 1443 male subjects aged more than 20 years who participated in the Nutrition and Health Survey in Taiwan (NAHSIT, 1993–1996). Anthropometric evaluation consisted of weight, height, hip and waist circumference (WC) with later body mass index (BMI), waist to height (WHtR) and waist to hip (WHR) estimations. We conducted 4 logistic models to determine the relationships between anthropometric indices and gout. Receiver operating characteristic (ROC) curve were used to compare the predictive performance and to identify the optimal cut-off points, sensitivity and specificity of these indices for gout in men. Results After controlling for other covariables, the adjusted odds ratios for the mid and top tertiles of WHtR were 2.55 (95% CI: 1.16, 5.59) and 3.01 (95% CI: 1.13, 7.99), respectively, but no linear association was found for BMI, WHR and WC. In ROC curve, the greatest area under curve was 0.684 for WHtR and the cut-off point of WHtR was 0.57. Conclusions WHtR had a significant linear association with gout in Taiwanese men and was superior to BMI, WHR and WC.
    Type of Medium: Online Resource
    ISSN: 1472-6823
    URL: Article
    DOI: 10.1186/1472-6823-13-30
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2091323-0
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