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  • Chen, Qin  (1,536)
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  • 1
    Online Resource
    Online Resource
    Daily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter study
    Springer Science and Business Media LLC ; 2023
    In:  Intensive Care Medicine Vol. 49, No. 4 ( 2023-04), p. 401-410
    Details
    In: Intensive Care Medicine, Springer Science and Business Media LLC, Vol. 49, No. 4 ( 2023-04), p. 401-410
    Type of Medium: Online Resource
    ISSN: 0342-4642 , 1432-1238
    URL: Article
    DOI: 10.1007/s00134-023-07006-x
    RVK:
    XA 10000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1459201-0
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  • 2
    Online Resource
    Online Resource
    2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS
    Springer Science and Business Media LLC ; 2020
    In:  Endocrine Vol. 70, No. 2 ( 2020-11), p. 256-279
    Details
    In: Endocrine, Springer Science and Business Media LLC, Vol. 70, No. 2 ( 2020-11), p. 256-279
    Type of Medium: Online Resource
    ISSN: 1355-008X , 1559-0100
    URL: Article
    DOI: 10.1007/s12020-020-02441-y
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2074043-8
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  • 3
    Online Resource
    Online Resource
    eHealth Literacy of Chinese Residents During the Coronavirus Disease 2019 Pandemic : A Cross-sectional Survey
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  CIN: Computers, Informatics, Nursing Vol. 41, No. 5 ( 2022-4-23), p. 292-299
    Details
    In: CIN: Computers, Informatics, Nursing, Ovid Technologies (Wolters Kluwer Health), Vol. 41, No. 5 ( 2022-4-23), p. 292-299
    Abstract: The Coronavirus Disease 2019 (COVID-19) pandemic has become a leading societal concern. eHealth literacy is important in the prevention and control of this pandemic. The purpose of this study is to identify eHealth literacy of Chinese residents about the COVID-19 pandemic and factors influencing eHealth literacy. A total of 15 694 individuals clicked on the link to the questionnaire, and 15 000 agreed to participate and completed the questionnaire for a response rate of 95.58%. Descriptive statistics, χ 2 test, and logistic regression analysis were conducted to analyze participants' level of eHealth literacy about COVID-19 and its influencing factors. The results showed 52.2% of participants had relatively lower eHealth literacy regarding COVID-19 (eHealth literacy score ≤ 48). The scores of the information judgment dimension (3.09 ± 0.71) and information utilization dimension (3.18 ± 0.67) of the eHealth literacy scale were relatively lower. The logistics regression showed that sex, age, education level, level of uncertainty, having people around the respondent diagnosed with COVID-19, relationship with family, and relationship with others were associated to eHealth literacy (χ 2 = 969.135, P 〈 .001). The public's eHealth literacy about COVID-19 needs to be improved, especially the ability to judge and utilize online information. Close collaboration among global health agencies, governments, healthcare institutions, and media is needed to provide reliable online information to the public. Interventions to improve eHealth literacy should take into account and accentuate the importance of sex, age, educational background, level of uncertainty, exposure to disease, and social support.
    Type of Medium: Online Resource
    ISSN: 1538-9774
    URL: Article
    DOI: 10.1097/CIN.0000000000000921
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2028462-7
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  • 4
    Online Resource
    Online Resource
    When health care workers became patients with COVID‐19: A qualitative study
    Wiley ; 2022
    In:  International Journal of Nursing Practice Vol. 28, No. 1 ( 2022-02)
    Details
    In: International Journal of Nursing Practice, Wiley, Vol. 28, No. 1 ( 2022-02)
    Abstract: What is already known about this topic? Health care workers, including nurses, are at the frontlines of the COVID‐19 outbreak and at high risk of infection. Experts have called for infection prevention for health care providers. Limited research has reported the experiences of health care workers infected by COVID‐19 using an empirical phenomenological approach. What this paper adds? Upon diagnosis, nurses and other health care workers experienced fear, uncertainty and distress like general patients. Health care workers reported moral distress about inadequate health care staffing issues. Health care workers could cope with their negative psychological reactions using professional knowledge and support from significant others and the community. The implications of this paper: Preparedness for large‐scale pandemics and a system that can provide openness and timely information needs consideration in policy development. Accurate information and good communication are vital to support infected health care workers and enhance their sense of safety and belonging. Long‐term support should be available when these health care workers return to work.
    Type of Medium: Online Resource
    ISSN: 1322-7114 , 1440-172X
    URL: Issue
    URL: Article
    DOI: 10.1111/ijn.v28.1
    DOI: 10.1111/ijn.13034
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2009434-6
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  • 5
    Online Resource
    Online Resource
    Potential Implications of the Lung Microbiota in Patients with Chronic Obstruction Pulmonary Disease and Non-Small Cell Lung Cancer
    Frontiers Media SA ; 2022
    In:  Frontiers in Cellular and Infection Microbiology Vol. 12 ( 2022-7-27)
    Details
    In: Frontiers in Cellular and Infection Microbiology, Frontiers Media SA, Vol. 12 ( 2022-7-27)
    Abstract: Recently, chronic obstructive pulmonary disease (COPD) has been considered as a common risk factor of non-small cell lung cancer (NSCLC). However, very few studies have been conducted on the effects of COPD on the lung microbiota in patients with NSCLC. To identify the lung microbiota in patients with COPD and NSCLC (CN), the microbiome of the induced sputa of 90 patients was analyzed using 16S rDNA sequencing. The results showed no significant differences in the bacterial diversities of induced sputa among patients with COPD, NSCLC, and CN and no intrinsic differences among patients with different pathological types of lung cancer. After surgical operation, the diversities of the induced sputa in patients with CN significantly decreased. More remarkably, both the microbial community phenotypes and the components of the induced sputa in patients with CN obviously differed from those in patients with COPD or NSCLC. The relative abundances of Streptococcus , Veillonella , Moraxella , and Actinomyces significantly decreased, but those of Neisseria and Acinetobacter significantly increased in patients with CN compared with those in patients with COPD or NSCLC alone, resulting in increased Gram-negative microbiota and, therefore, in potential pathogenicity and stress tolerance, as well as in enhancement of microbial glycolipid metabolism, amino acid metabolism, and oxidative stress. Although COPD did not affect the number of pulmonary flora species in patients with NSCLC, these significant alterations in the microbial populations, phenotypes, and functions of induced sputa due to COPD would contribute to inflammation-derived cancer progression in patients with CN.
    Type of Medium: Online Resource
    ISSN: 2235-2988
    URL: Article
    DOI: 10.3389/fcimb.2022.937864
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2619676-1
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  • 6
    Online Resource
    Online Resource
    The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters
    Springer Science and Business Media LLC ; 2023
    In:  Nature Communications Vol. 14, No. 1 ( 2023-08-29)
    Details
    In: Nature Communications, Springer Science and Business Media LLC, Vol. 14, No. 1 ( 2023-08-29)
    Abstract: The piRNA pathway is essential for female fertility in golden hamsters and likely humans, but not in mice. However, the role of individual PIWIs in mammalian reproduction remains poorly understood outside of mice. Here, we describe the expression profiles, subcellular localization, and knockout-associated reproductive defects for all four PIWIs in golden hamsters. In female golden hamsters, PIWIL1 and PIWIL3 are highly expressed throughout oogenesis and early embryogenesis, while knockout of PIWIL1 leads to sterility, and PIWIL3 deficiency results in subfertility with lagging zygotic development. PIWIL1 can partially compensate for TE silencing in PIWIL3 knockout females, but not vice versa. PIWIL1 and PIWIL4 are the predominant PIWIs expressed in adult and postnatal testes, respectively, while PIWIL2 is present at both stages. Loss of any PIWI expressed in testes leads to sterility and severe but distinct spermatogenesis disorders. These findings illustrate the non-redundant regulatory functions of PIWI-piRNAs in gametogenesis and early embryogenesis in golden hamsters, facilitating study of their role in human fertility.
    Type of Medium: Online Resource
    ISSN: 2041-1723
    URL: Article
    DOI: 10.1038/s41467-023-40650-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2553671-0
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  • 7
    Online Resource
    Online Resource
    A Review on the High Sound Pressure Level Acoustic Measurement in the Aerospace Field
    Hindawi Limited ; 2023
    In:  Journal of Sensors Vol. 2023 ( 2023-3-31), p. 1-10
    Details
    In: Journal of Sensors, Hindawi Limited, Vol. 2023 ( 2023-3-31), p. 1-10
    Abstract: Noise could occur anywhere in the aerospace and other fields and has a great influence on the operation of the aircraft. The control of the sound emission has attracted a lot of attention from the economic and environmental aspects. Firstly, the noise is annoying for the passengers and pilot and may increase the risk to be exposed for the military applications. Secondly, the sound emission may pose a great damage and threat to the engine equipment due to the strong pressure oscillation. In addition, the combustion noise may also have a great influence on the combustion process in the engine, which may lead to the emission increase and low-efficiency operation. The noise emission measurement is necessary and very important for the research in aerospace field. The aircraft in aerospace field usually works in the extreme environment, and the noise emission is within a high sound pressure level, which is quite from the acoustic measurement in other fields. Thus, we give a short review to introduce the high sound pressure level acoustic measurement in the aerospace field.
    Type of Medium: Online Resource
    ISSN: 1687-7268 , 1687-725X
    URL: Article
    DOI: 10.1155/2023/6681598
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2023
    detail.hit.zdb_id: 2397931-8
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  • 8
    Online Resource
    Online Resource
    Intermittent versus continuous control of tracheal cuff pressure in patients undergoing mechanical ventilation: A systematic review and meta‐analysis
    Wiley ; 2023
    In:  Journal of Clinical Nursing Vol. 32, No. 15-16 ( 2023-08), p. 4283-4294
    Details
    In: Journal of Clinical Nursing, Wiley, Vol. 32, No. 15-16 ( 2023-08), p. 4283-4294
    Abstract: To evaluate the effects and safety of intermittent versus continuous control of cuff pressure in patients with mechanical ventilation. Background Tracheal cuff pressure management is vital to the prognosis of patients with mechanical ventilation. Design A meta‐analysis. Methods This meta‐analysis was conducted and reported according to the PRISMA checklist. We searched Pubmed, Embase, The Cochrane Library, BMJ Best Practice, Web of Science, ProQuest Dissertations, as well as the Chinese Biomedical Literature Database, Wanfang, and China national knowledge infrastructure databases up to 5 August 2022 for randomised controlled trials (RCTs) on the intermittent versus continuous control of cuff pressure. Review Manager 5.3 software was used for relevant data analysis. Results A total of 18 RCTs involving 1998 patients with mechanical ventilation were included. The synthesised outcomes indicated that continuous control of cuff pressure is beneficial to reduce the incidence of ventilator‐associated pneumonia (VAP) [RR = 0.41, 95%CI (0.35, 0.49)], aspiration [RR = 0.36, 95%CI (0.21, 0.63)] , duration of mechanical ventilation [MD = ‐3.23, 95%CI (−4.66, −1.79)], length of ICU stay [MD = ‐4.12, 95%CI (−5.40, −2.83)] , and increase the volume of subglottic drainage [MD = 18.54, 95%CI (16.50, 20.58)]. There was no significant difference in the mortality between two groups [RR = 1.01, 95%CI (0.84, 1.21)] . Egger regression analyses showed that there were no obvious publication biases in the synthesised results (all p   〉  .05). Conclusions Existing evidence shows that compared with intermittent monitoring of cuff pressure, continuous monitoring of cuff pressure can reduce the occurrence of aspiration and VAP, shorten the patient's duration of mechanical ventilation and length of ICU stay. Relevance to Clinical Practice Continuous monitoring of cuff pressure is more beneficial and should be promoted in clinical nursing care of patients undergoing mechanical ventilation.
    Type of Medium: Online Resource
    ISSN: 0962-1067 , 1365-2702
    URL: Issue
    URL: Article
    DOI: 10.1111/jocn.v32.15-16
    DOI: 10.1111/jocn.16619
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2006661-2
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  • 9
    Online Resource
    Online Resource
    A quick and efficient hydroponic potato infection method for evaluating potato resistance and Ralstonia solanacearum virulence
    Springer Science and Business Media LLC ; 2019
    In:  Plant Methods Vol. 15, No. 1 ( 2019-12)
    Details
    In: Plant Methods, Springer Science and Business Media LLC, Vol. 15, No. 1 ( 2019-12)
    Abstract: Potato, the third most important crop worldwide, plays a critical role in human food security. Brown rot, one of the most destructive potato diseases caused by Ralstonia solanacearum , results in huge economic losses every year. A quick, stable, low cost and high throughout method is required to meet the demands of identification of germplasm resistance to bacterial wilt in potato breeding programs. Results Here we present a novel R. solanacearum hydroponic infection assay on potato plants grown in vitro. Through testing wilt symptom appearance and bacterial colonization in aerial part of plants, we found that the optimum conditions for in vitro potato infection were using an OD 600 0.01 bacterial solution suspended with tap water for infection, broken potato roots and an open container. Infection using R. solanacearum strains with differential degree of aggressivity demonstrated that this infection system is equally efficient as soil-drench inoculation for assessment of R. solanacearum virulence on potato. A small-scale assessment of 32 potato germplasms identified three varieties highly resistant to the pathogen, which indicates this infection system is a useful method for high-throughout screening of potato germplasm for resistance. Furthermore, we demonstrate the utility of a strain carrying luminescence to easily quantify bacterial colonization and the detection of latent infections in hydroponic conditions, which can be efficiently used in potato breeding programs. Conclusions We have established a quick and efficient in vitro potato infection system, which may facilitate breeding for new potato cultivars with high resistance to R. solanacearum .
    Type of Medium: Online Resource
    ISSN: 1746-4811
    URL: Article
    DOI: 10.1186/s13007-019-0530-9
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2203723-8
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    Global Profiling of Dynamic Alternative Splicing Modulation in Arabidopsis Root upon Ralstonia solanacearum Infection
    MDPI AG ; 2020
    In:  Genes Vol. 11, No. 9 ( 2020-09-15), p. 1078-
    Details
    In: Genes, MDPI AG, Vol. 11, No. 9 ( 2020-09-15), p. 1078-
    Abstract: Alternative splicing (AS) is an important mechanism by which eukaryotes regulate transcription and protein diversity. The dynamic changes in AS that occur on a genome-wide scale during interactions between plant roots and pathogens remain unknown. Here, we used the interaction between Arabidopsis and Ralstonia solanacearum as a model to explore the AS changes that take place during the response of roots to infection by means of high-throughput RNA-sequencing. We showed that dynamic changes in AS occur much earlier than changes at the level of transcription during R.solanacearum infection. Comparing genes that are regulated at the transcriptional and AS levels indicated that there are few common genes between differentially spliced genes (DSGs) and differentially expressed genes (DEGs). The functional gene ontology (GO) analysis identified that the enriched GO terms for the DSGs were different from those of the DEGs. The DSGs were over-represented in GO terms associated with post-transcriptional and translational regulations, suggesting that AS may act on RNA stability and during post-translation, thus affecting the output of plant defense molecules. Meanwhile, changes in DSGs were infection stage-specific. Furthermore, the nucleotide binding domain and leucine-rich repeat proteins and receptor-like kinases, key regulators in plant immunity, were shown to undergo dynamic changes in AS in response to R. solanacearum. Taken together, AS, along with transcription, modulates plant root defense to R. solanacearum through transcriptome reprogramming.
    Type of Medium: Online Resource
    ISSN: 2073-4425
    URL: Article
    DOI: 10.3390/genes11091078
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2527218-4
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