In:
Journal of Heterocyclic Chemistry, Wiley, Vol. 55, No. 6 ( 2018-06), p. 1382-1390
Abstract:
A series of novel quinazolinone acylhydrazone derivatives containing the indole moiety were designed, synthesized, and evaluated for their inhibition activities against some important phytopathogens in vitro . Antibacterial experiments indicated that some compounds exhibited remarkable inhibition activities against tested bacteria. Especially, the EC 50 values of 7a (EC 50 = 55.13 μg/mL against Xoo , EC 50 = 56.92 μg/mL against Rs ) demonstrated the best antibacterial activities against Xoo and Rs than the other compounds, and the control agents Bismerthiazol (EC 50 = 89.80 μg/mL against Xoo ) and Thiodiazole copper (EC 50 = 189.52 μg/mL against Rs ), moreover, compound 7o (EC 50 = 50.80 μg/mL) displayed the excellent activity against Xac than the control Bismerthiazol (EC 50 = 56.92 μg/mL).
Type of Medium:
Online Resource
ISSN:
0022-152X
,
1943-5193
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2042274-X
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