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  • Frontiers Media SA  (148)
  • Chen, Jie  (148)
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  • Frontiers Media SA  (148)
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  • 1
    Online Resource
    Online Resource
    A Comprehensive Game Theoretical Defense Strategy in Demand Side Management Against Price Tampering Attacks
    Frontiers Media SA ; 2021
    In:  Frontiers in Energy Research Vol. 9 ( 2021-11-25)
    Details
    In: Frontiers in Energy Research, Frontiers Media SA, Vol. 9 ( 2021-11-25)
    Abstract: Price tamping attacks may cause market turbulence, attack detection and defense strategy are needed to study. Firstly, demand response characteristics are analyzed in a User Energy System. A quantitative model is established to describe the load changes caused by price tampering attacks. Secondly, a space-based cumulative intrusion detection method is proposed to pick up the discrepancy under tampering attacks. To verify the practicability of the proposed method, intrusion detection experiments are tested in the Principal Information and Safety Laboratory. Then, comprehensively considering the purchase of electricity from the power grid, self-generation, and load shedding, a quantitative model of attack consequences is established based on the allocation coefficient. Thus, the intrusion detection algorithm is used as a defense resource, and a demand-side defense protection strategy is formed to find an optimal deployment method based on non-cooperative game theory. The defensive protection strategy takes the quantitative model of attack consequences as the solution target, and solves the Nash equilibrium solution under different attack modes. Finally, in the IEEE-33 node system simulations, the defense resource is deployed using intrusion detection strategy, and the defense decision is executed to show the effectiveness of the comprehensive protection strategies.
    Type of Medium: Online Resource
    ISSN: 2296-598X
    URL: Article
    DOI: 10.3389/fenrg.2021.763260
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2733788-1
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  • 2
    Online Resource
    Online Resource
    17-β-Estradiol and Progesterone as Efficient Predictors of Survival in Older Women Undergoing Hip Fracture Surgery
    Frontiers Media SA ; 2020
    In:  Frontiers in Medicine Vol. 7 ( 2020-8-7)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 7 ( 2020-8-7)
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    DOI: 10.3389/fmed.2020.00345
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2020
    detail.hit.zdb_id: 2775999-4
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  • 3
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    Table_1.DOCX
    Frontiers Media SA ; 2019
    In:  Frontiers in Neurology Vol. 10 ( 2019-6-4)
    Details
    In: Frontiers in Neurology, Frontiers Media SA, Vol. 10 ( 2019-6-4)
    Type of Medium: Online Resource
    ISSN: 1664-2295
    URL: Article
    URL: Article
    DOI: 10.3389/fneur.2019.00592
    DOI: 10.3389/fneur.2019.00592.s002
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2019
    detail.hit.zdb_id: 2564214-5
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  • 4
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    Table_1.docx
    Frontiers Media SA ; 2021
    In:  Frontiers in Nutrition Vol. 8 ( 2021-5-13)
    Details
    In: Frontiers in Nutrition, Frontiers Media SA, Vol. 8 ( 2021-5-13)
    Abstract: Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Folate has been demonstrated to be associated with ASD. However, current studies on the correlation between folate and symptoms of children with ASD have inconsistent conclusions, use mainly small samples, and lack age-stratified analysis. This study aimed to explore the association between serum folate and symptoms of autistic children at different age groups from a multi-center perspective. Methods: We enrolled 1,300 children with ASD and 1,246 typically developing (TD) children under 7 years old from 13 cities in China. The Autism Behavior Checklist (ABC), Social Responsiveness Scale (SRS), and Childhood autism rating scale (CARS) were used to evaluate the symptoms of children with ASD. China neuropsychological and Behavior Scale-Revision 2016 (CNBS-R2016) scale was used to evaluate the neurodevelopment of children with ASD. Serum folate was measured by chemiluminescence assay in the two groups. Results: The serum folate levels of children with ASD were lower than that of TD children. In terms of core symptoms of ASD, we found that the serum folate levels were not associated with ABC, SRS, and CARS scores in ASD children of all ages but negatively associated with communication warning behavior scores of CNBS-R2016 in ASD children aged three and under. Concerning development quotients, it was at the age of three and under that serum folate levels were positively associated with gross motor, fine motor, language, and general quotient of ASD children. These ASD children aged three and under were further divided into two groups according to the median of serum folate (14.33 ng/mL); we found that compared to ASD children with folate ≤ 14.33 ng/mL, those with folate & gt;14.33 ng/mL had lower communication warning behavior score and higher gross motor, fine motor, adaptive behavior, language, person-social, and general development quotients. Conclusion: We found that serum folate status was primarily associated with the neurodevelopment of children with ASD aged three and under. Furthermore, relatively higher serum folate levels may be more beneficial for children with ASD. Our results suggest that folate level should be paid more attention in ASD children, especially in early life, to better promote the intervention of ASD children.
    Type of Medium: Online Resource
    ISSN: 2296-861X
    URL: Article
    URL: Article
    DOI: 10.3389/fnut.2021.661223
    DOI: 10.3389/fnut.2021.661223.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2776676-7
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  • 5
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    Online Resource
    Table_4.xlsx
    Frontiers Media SA ; 2021
    In:  Frontiers in Plant Science Vol. 12 ( 2021-5-26)
    Details
    In: Frontiers in Plant Science, Frontiers Media SA, Vol. 12 ( 2021-5-26)
    Abstract: Understanding the roles played by geography and ecology in driving species diversification and in the maintenance of species cohesion is the central objective of evolutionary and ecological studies. The multi-phased orogenesis of Qinghai-Tibetan Plateau (QTP) and global climate changes over late-Miocene has profoundly influenced the environments and evolution of organisms in this region and the vast areas of Asia. In this study, we investigate the lineage diversification of Chrysanthemum -group in subtribe Artemisiinae (tribe Anthemideae, Asteraceae) likely under the effects of climate changes during this period. Using DNA sequences of seven low-copy nuclear loci and nrITS and the coalescent analytical methods, a time-calibrated phylogeny of subtribe Artemisiinae was reconstructed with emphasis on Chrysanthemum -group. The monophyletic Chrysanthemum- group was well resolved into two major clades corresponding to Chrysanthemum and Ajania , two genera which can be well identified by capitulum morphology but have been intermingled in previous plastid and ITS trees. Within Chrysanthemum , a later divergence between Ch. indicum -complex and Ch. zawadskii -complex can be recognized. The time frames of these sequential divergences coincide with the late Cenozoic uplift of the Northern QTP and the concomitant climatic heterogeneity between eastern and inland Asia. Reconstruction of historical biogeography suggested the origin of Chrysanthemum -group in Central Asia, followed by eastward migration of Chrysanthemum and in situ diversification of Ajania . Within Chrysanthemum , Ch. indicum -complex and Ch. zawadskii -complex exhibited contemporary distributional division, the former in more southern and the latter in more northern regions. The geographic structure of the three lineages in Chrysanthemum -group have been associated with the niche differentiation, and environmental heterogenization in Asia interior.
    Type of Medium: Online Resource
    ISSN: 1664-462X
    URL: Article
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    DOI: 10.3389/fpls.2021.648026
    DOI: 10.3389/fpls.2021.648026.s001
    DOI: 10.3389/fpls.2021.648026.s002
    DOI: 10.3389/fpls.2021.648026.s003
    DOI: 10.3389/fpls.2021.648026.s004
    DOI: 10.3389/fpls.2021.648026.s005
    DOI: 10.3389/fpls.2021.648026.s006
    DOI: 10.3389/fpls.2021.648026.s007
    DOI: 10.3389/fpls.2021.648026.s008
    DOI: 10.3389/fpls.2021.648026.s009
    DOI: 10.3389/fpls.2021.648026.s010
    DOI: 10.3389/fpls.2021.648026.s011
    DOI: 10.3389/fpls.2021.648026.s012
    DOI: 10.3389/fpls.2021.648026.s013
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2687947-5
    detail.hit.zdb_id: 2613694-6
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  • 6
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    Vitamin A Status Is More Commonly Associated With Symptoms and Neurodevelopment in Boys With Autism Spectrum Disorders—A Multicenter Study in China
    Frontiers Media SA ; 2022
    In:  Frontiers in Nutrition Vol. 9 ( 2022-4-5)
    Details
    In: Frontiers in Nutrition, Frontiers Media SA, Vol. 9 ( 2022-4-5)
    Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder, and show a striking male bias in prevalence. Vitamin A (VA) is essential for brain development, and abnormalities in its metabolite retinoic acid are associated with the pathophysiology of ASD. This national multicenter study was conducted to investigate the relationship between serum VA level and core symptoms in ASD children and whether there are still sex differences. Method A total of 1,300 children with ASD and 1,252 typically-developing (TD) controls aged 2–7 years old from 13 cities in China were enrolled in this study. The symptoms of children with ASD were evaluated by the Autism Behavior Checklist (ABC), Social Responsiveness Scale (SRS), and Childhood autism rating scale (CARS). The neurodevelopmental level of the children was evaluated with the revised Children Neuropsychological and Behavior Scale (CNBS-R2016). The serum level of VA was measured by high-performance liquid chromatography (HPLC). Results The serum VA level in children with ASD was significantly lower than that in TD children, especially in boys with ASD. Furthermore, VA levels in male children with ASD were lower than those in female children with ASD. In addition, we found that serum VA level was negatively correlated the SRS, CARS and communication warming behavior of CBNS-R2016 scores in boys with ASD. In terms of developmental quotients, serum VA level was positively associated with the general quotient, language quotient, gross motor quotient and personal-social quotient of boys with ASD, but no difference was found in girls with ASD. Conclusions ASD children, especially boys, have lower serum VA levels than TD children. Moreover, serum VA status is more commonly associated with clinical symptoms and neurodevelopment in boys with ASD.
    Type of Medium: Online Resource
    ISSN: 2296-861X
    URL: Article
    DOI: 10.3389/fnut.2022.851980
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2776676-7
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  • 7
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    A Multi-Center Study on the Relationship Between Developmental Regression and Disease Severity in Children With Autism Spectrum Disorders
    Frontiers Media SA ; 2022
    In:  Frontiers in Psychiatry Vol. 13 ( 2022-3-9)
    Details
    In: Frontiers in Psychiatry, Frontiers Media SA, Vol. 13 ( 2022-3-9)
    Abstract: This study aimed to investigate the prevalence of developmental regression in children with Autism Spectrum Disorder (ASD) and to explore its relationship with disease severity. Methods We finally included 1,027 ASD children aged 2–5 years from 13 cities in China: 138 with regressive ASD and 889 with non-regressive ASD. The Social Responsiveness Scale (SRS), Autism Behavior Checklist (ABC), Child Autism Rating Scale (CARS), and Children Neuropsychological and Behavioral Scale-Revision 2016 (CNBS-R2016) were used to evaluate the core symptoms and developmental status of children in the two groups. Results Among the 1,027 ASD children eventually included, 138 (13.44%) cases showed regressive behavior and the average regression occurring age was 24.00 (18.00–27.00) months. Among the regressive children, 105 cases (76.09%) had language regression, 79 cases (57.25%) had social regression, and 4 cases (2.90%) had motor regression. The total scores of ABC and the sub-score of sensory and stereotypic behavior (β = 5.122, 95% CI: 0.818, 9.426, P & lt; 0.05; β = 1.104, 95% CI: 0.120, 2.089, P & lt; 0.05; β = 1.388, 95% CI: 0.038, 2.737, P & lt; 0.05), the SRS total scores and the sub-score of autistic mannerisms (β = 4.991, 95% CI: 0.494, 9.487, P & lt; 0.05; β = 1.297, 95% CI: 0.140, 2.453, P & lt; 0.05) of children in the regressive group were all higher than the non-regressive group. The total developmental quotient (DQ) of CNBS-R2016 and the DQ of gross motor, fine motor, adaptive behavior, language (β = −5.827, 95% CI: −11.529, −0.125, P & lt; 0.05) and personal society in the regressive group were lower than the non-regressive group and the proportion of children with intelligent developmental impairment was higher the non-regressive group. Conclusion Regressive autism is mainly manifested as language and social regression. Children with regressive ASD have more severe core symptoms, lower neurodevelopmental level DQ, and more serious disease degree than children with non-regressive ASD, which requires further etiological examinations and more clinical attention.
    Type of Medium: Online Resource
    ISSN: 1664-0640
    URL: Article
    DOI: 10.3389/fpsyt.2022.796554
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2564218-2
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  • 8
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    Low-carbon economic dispatch of integrated energy system based on liquid carbon dioxide energy storage
    Frontiers Media SA ; 2023
    In:  Frontiers in Energy Research Vol. 10 ( 2023-1-17)
    Details
    In: Frontiers in Energy Research, Frontiers Media SA, Vol. 10 ( 2023-1-17)
    Abstract: To realize the integrated energy system (IES) low-carbon and economy dispatches and renewable energy utilization, the integrated energy system economic dispatch model introduces the liquid carbon dioxide energy storage (LCES) and carbon capture system (CCS). This paper proposes a low-carbon economic dispatch model for an integrated energy system that considers LCES and carbon capture system. The paper considers the impact of carbon trading mechanisms on systemic carbon emissions, aims to minimize the total operating cost of the system, and comparison of integrated energy system dispatch for two scenarios: integrated energy system equipped with LCES and integrated energy system equipped with battery energy storage. CPLEX simulation software simulates this comprehensive energy system. Analyzing the dispatching results from different perspectives, such as electric energy, thermal energy, and CO 2 emissions. These results show that the proposed model effectively reduces carbon emissions, improves energy utilization, and achieves comprehensive low-carbon economic operation of the integrated energy system.
    Type of Medium: Online Resource
    ISSN: 2296-598X
    URL: Article
    DOI: 10.3389/fenrg.2022.1051630
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2733788-1
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  • 9
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    DataSheet_1.csv
    Frontiers Media SA ; 2022
    In:  Frontiers in Immunology Vol. 13 ( 2022-10-25)
    Details
    In: Frontiers in Immunology, Frontiers Media SA, Vol. 13 ( 2022-10-25)
    Abstract: The role of normal gut microbiota in asthma or ovalbumin (OVA)-induced asthma tolerance (OT) remains unclear. Here, we established mouse models of asthma and OT followed by 2 weeks of antibiotic treatment, to clear the gut microbiota. Antibiotic treatment was found to alleviate allergic asthma accompanied with a reduction of invariant natural killer (iNKT) cells. By RNA-seq analysis, we found that β-adrenergic receptor (ADRB) genes, including Adrb1 , Adrb2 , and Adrb3 , were downregulated in asthmatic lungs, but these changes were reversed in OT lungs. Moreover, Adrb2 and Adrb3 were significantly upregulated in asthmatic lungs after antibiotic treatment. Surprisingly, blocking ADRB with propranolol relieved allergic asthma while reducing T helper 2 (Th2) and Treg cell numbers. Further analyses using flow cytometry and immunofluorescence showed that the protein expression level of ADRB2 was higher in asthmatic lungs than that in the control and OT lungs. Notably, dendritic cells (DCs), especially the ADRB2 + DCs, were increased in asthmatic lungs compared to that in the control and OT lungs. In addition, ADRB2 + DCs were significantly reduced following the administration of the ADRB2-specific antagonist ICI118551. Our findings suggest that antibiotic treatment can alleviate OVA-induced allergic asthma via reducing the frequency of iNKT cells and function of ADRB2.
    Type of Medium: Online Resource
    ISSN: 1664-3224
    URL: Article
    URL: Article
    DOI: 10.3389/fimmu.2022.1024235
    DOI: 10.3389/fimmu.2022.1024235.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2606827-8
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  • 10
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    Heterogeneous Influence of Frailty Phenotypes in Age-Related Hearing Loss and Tinnitus in Chinese Older Adults: An Explorative Study
    Frontiers Media SA ; 2021
    In:  Frontiers in Psychology Vol. 11 ( 2021-2-16)
    Details
    In: Frontiers in Psychology, Frontiers Media SA, Vol. 11 ( 2021-2-16)
    Abstract: Fried physical frailty, with mobility frailty and non-motor frailty phenotypes, is a heterogeneous syndrome. The coexistence of the two phenotypes and cognitive impairment is referred to as cognitive frailty (CF). It remains unknown whether frailty phenotype has a different association with hearing loss (HL) and tinnitus. Methods Of the 5,328 community-dwelling older adults, 429 participants aged ≥58 years were enrolled in the study. The participants were divided into robust, mobility, and non-mobility frailty, mobility and non-mobility CF (subdivided into reversible and potentially reversible CF, RCF, and PRCF), and cognitive decline [subdivided into mild cognitive impairment (MCI) and pre-MCI] groups. The severity and presentations of HL and/or tinnitus were used as dependent variables in the multivariate logistic or nominal regression analyses with forward elimination adjusted for frailty phenotype stratifications and other covariates. Results Patients with physical frailty (mobility frailty) or who are robust were found to have lower probability of developing severe HL and tinnitus, and presented HL and/or tinnitus than those with only cognitive decline, or CF. Patients with RCF and non-mobility RCF had higher probability with less HL and tinnitus, and the presentation of HL and/or tinnitus than those with PRCF and mobility RCF. Other confounders, age, cognitive and social function, cardiovascular disease, depression, and body mass index, independently mediated the severity of HL and tinnitus, and presented HL and/or tinnitus. Conclusion Frailty phenotypes have divergent association with HL and tinnitus. Further research is required to understand the differential mechanisms and the personalized intervention of HL and tinnitus. Clinical Trial Registration ClinicalTrials.gov identifier, NCT2017K020.
    Type of Medium: Online Resource
    ISSN: 1664-1078
    URL: Article
    DOI: 10.3389/fpsyg.2020.617610
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2563826-9
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