In:
AIDS, Ovid Technologies (Wolters Kluwer Health), Vol. 37, No. 4 ( 2023-03-15), p. 611-616
Abstract:
To compare characteristics and clinical manifestations of monkeypox (MPX) between people with and without HIV in the United States. Design: Retrospective cohort study using TriNetX, a federated research network. Methods: Patients 18 years and older with MPX were identified based on the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis code B04 and divided into two groups: people with HIV (PWH) and people without HIV. Differences in baseline characteristics, clinical manifestations, and all-cause healthcare utilization were examined between groups. Outcomes were reported before and after propensity score matching. Results: Of 322 cases of MPX included, 29% ( n = 93) were PWH. Baseline characteristics were similar, but PWH were more likely to identify as Black or African American persons (24% vs. 11%, P = 0.0303) or as Hispanic or Latino persons (24% vs. 11%, P = 0.0345) and more likely to report lifestyle factors affecting health status. Rash and rectal pain were more common in PWH (25% vs. 11%, P 〈 0.01, and 25% vs. 10%, P 〈 0.001, respectively). In addition, PWH had higher rates of anal or rectal abscesses (11% vs. 0%, P 〈 0.0001), phimosis (11% vs. 0%, P 〈 0.0001), and pneumonia (11% vs. 0%, P 〈 0.0001). More PWH required urgent care visits (53% vs. 29%, P 〈 0.0001) and hospitalizations (11% vs. 4%, P = 0.0314), but not emergency department visits (42% vs. 58%, P = 0.0085). Conclusion: PWH had higher rates of clinical manifestations and required greater utilization of healthcare resources for any reason compared with those without HIV.
Type of Medium:
Online Resource
ISSN:
0269-9370
,
1473-5571
DOI:
10.1097/QAD.0000000000003449
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2023
detail.hit.zdb_id:
2012212-3
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