In:
International Journal of Dermatology, Wiley, Vol. 56, No. 6 ( 2017-06), p. 617-622
Abstract:
Cutaneous lymphomas are a heterogeneous group of tumors with various clinical manifestations, histological features, and prognoses. Methods Among 425 cases of cutaneous lymphoma, we describe eight cases of peripheral T‐cell lymphoma, unspecified, presenting with generalized benign‐looking dermatitis. Results Our case series included eight cases of secondary cutaneous peripheral T‐cell lymphoma, unspecified. The observed clinical morphology features included drug eruption‐like generalized morbilliform maculopatches in two cases, generalized folliculitis‐like papules in two cases, and generalized eczematous dermatitis‐like papules and patches in four cases. Histopathological examination demonstrated tumor cell infiltrates of mainly atypical, small‐to‐medium lymphoid cells that were perivascularly or periadnexally distributed throughout the dermis. Immunohistochemical staining results for CD 2, CD 3, CD 4, and CD 8 revealed that the tumor cells were T‐cells. Conclusion This collection of cases and literature review emphasizes the need for clinical suspicion of peripheral T‐cell lymphoma, unspecified, in the differential diagnosis of adult patients with refractory eczematous or benign‐looking skin lesions.
Type of Medium:
Online Resource
ISSN:
0011-9059
,
1365-4632
DOI:
10.1111/ijd.2017.56.issue-6
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2020365-2
Permalink