In:
Journal of the American Heart Association, Ovid Technologies (Wolters Kluwer Health), Vol. 5, No. 4 ( 2016-04-03)
Abstract:
As part of its 2020 Impact Goals, the American Heart Association developed the Life's Simple 7 metric for cardiovascular health promotion. The relationship between the Life's Simple 7 metric and incident chronic kidney disease ( CKD ) is unknown. Methods and Results We estimated the association between Life's Simple 7 and incident CKD in 14 832 Atherosclerosis Risk in Communities study participants. Ideal levels of Life's Simple 7 health factors were the following: nonsmoker or quit 〉 1 year ago; body mass index 〈 25 kg/m 2 ; ≥150 minutes/week of physical activity; healthy dietary pattern (high in fruits and vegetables, fish, and fiber‐rich whole grains; low in sodium and sugar‐sweetened beverages); total cholesterol 〈 200 mg/dL; blood pressure 〈 120/80 mm Hg; and fasting blood glucose 〈 100 mg/dL. At baseline, mean age was 54 years, 55% were women, and 26% were African American. There were 2743 incident CKD cases over a median follow‐up of 22 years. Smoking, body mass index, physical activity, blood pressure, and blood glucose were associated with CKD risk (all P 〈 0.01), but diet and blood cholesterol were not. CKD risk was inversely related to the number of ideal health factors ( P ‐trend 〈 0.001). A model containing the Life's Simple 7 health factors was more predictive of CKD risk than the base model including only age, sex, race, and estimated glomerular filtration rate (Life's Simple 7 health factors area under the ROC curve: 0.73, 95% CI : 0.72, 0.74 versus base model area under the ROC curve: 0.68, 95% CI : 0.67, 0.69; P 〈 0.001). Conclusions The AHA 's Life's Simple 7 metric, developed to measure and promote cardiovascular health, predicts a lower risk of CKD .
Type of Medium:
Online Resource
ISSN:
2047-9980
DOI:
10.1161/JAHA.116.003192
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2016
detail.hit.zdb_id:
2653953-6
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