In:
CURRENT TOPICS IN NUTRACEUTICAL RESEARCH, New Century Health Publishers LLC, Vol. 21, No. 1 ( 2023-01-06), p. 60-65
Kurzfassung:
We have isolated 15 bacterial strains from Aloe vera gel. Among them, we selected the Lactococcus lactis subsp. hordniae strain UAB10 based on its inhibition of IL-6-induced STAT3 activation and its ability to adhere to intestinal epithelial cells. UAB10 showed strong inhibition of interleukin-6-induced signal transducer and activator of transcription 3 activation. The UAB10 isolate showed superior adhesion to Caco-2 cells compared with KTCT 3768, a reference L. lactis subsp. hordniae strain. The UAB10 isolate displayed no hemolytic activity and more potent anti-Shigella flexneri activity than KTCT 3768. Furthermore, UAB10 was able to survive better than KTCT 3768 in oxgall-containing De Man, Rogosa, and Sharpe agar media and low-pH De Man, Rogosa, and Sharpe agar media. Finally, UAB10 did not show any resistance against the eight tested antibiotics, including ampicillin, vancomycin, and gentamicin. These results highlight the potential for the use of UAB10 as a commercial probiotic.
Materialart:
Online-Ressource
ISSN:
1540-7535
,
2641-452X
DOI:
10.37290/ctnr2641-452X.21:60-65
Sprache:
Unbekannt
Verlag:
New Century Health Publishers LLC
Publikationsdatum:
2023
ZDB Id:
2455097-8
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