In:
Advanced Synthesis & Catalysis, Wiley, Vol. 363, No. 1 ( 2021-01-05), p. 194-199
Abstract:
The formation of hydrazinium salts by N−N bond formation has typically involved the use of hazardous and difficult to handle reagents. Here, mild and operationally simple conditions for the synthesis of hydrazinium salts are reported. Electrophilic nitrogen transfer to the nitrogen atom of tertiary amines is achieved using iodosylbenzene as oxidant and ammonium carbamate as the N‐source. The resulting process is highly chemoselective and tolerant to other functional groups. A wide scope is reported, including examples with bioactive molecules. Insights on the structure of hydrazinium salts were provided by X‐ray analysis. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.202001047
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
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