In:
Epidemiology and Infection, Cambridge University Press (CUP), Vol. 116, No. 2 ( 1996-04), p. 185-192
Abstract:
An outbreak of legionellosis associated with a hotel in Sydney, Australia, and the subsequent epidemiological and environmental investigations are described. Four cases of Legionnaires' disease were notified to the Public Health Unit. A cross-sectional study of 184 people who attended a seminar at the hotel was carried out. Serological and questionnaire data were obtained for 152 (83%) of these. Twenty-eight (18%) respondents reported symptoms compatible with legionellosis. Thirty-three subjects (22%) had indirect fluorescent antibody (IFA) titres to Legionella pneumophila serogroup 1 (Lp-1) of 128 or higher. The only site which those with symptoms of legionellosis and IFA titre ≥128 were more likely to have visited than controls was the hotel car park (adjusted odds ratio [OR] 14·7, 95% confidence interval [CI] : 1·8–123·1). Those with symptoms compatible with legionellosis, but whose IFA titres were 〈 128 were also more likely to have visited the hotel car park (adjusted OR 4·4, 95% CI: 1·5–12·9). Seroprevalence of Lp-1 antibodies was higher in those who attended the seminar than in a population sample of similar age. Findings suggested that the 4 cases represented a small fraction of all those infected, and highlighted difficulties in defining illness caused by Lp-1 and in interpreting serology.
Type of Medium:
Online Resource
ISSN:
0950-2688
,
1469-4409
DOI:
10.1017/S0950268800052420
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
1996
detail.hit.zdb_id:
1470211-3
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