In:
Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 98, No. 11 ( 2001-05-22), p. 6511-6515
Abstract:
In tomato, Ve is implicated in race-specific
resistance to infection by Verticillium species causing
crop disease. Characterization of the Ve locus involved
positional cloning and isolation of two closely linked inverted genes. Expression of individual Ve genes in susceptible potato
plants conferred resistance to an aggressive race 1 isolate of Verticillium albo-atrum . The deduced primary structure
of Ve 1 and Ve 2 included a hydrophobic
N-terminal signal peptide, leucine-rich repeats containing 28 or 35 potential glycosylation sites, a hydrophobic membrane-spanning domain,
and a C-terminal domain with the mammalian E/DXXXLφ or YXXφ endocytosis signals (φ is an amino acid with a hydrophobic side
chain). A leucine zipper-like sequence occurs in the hydrophobic N-terminal signal peptide of Ve 1 and a Pro-Glu-Ser-Thr
(PEST)-like sequence resides in the C-terminal domain of Ve 2. These structures suggest that the Ve genes encode a class of cell-surface glycoproteins with
receptor-mediated endocytosis-like signals and leucine zipper or PEST sequences.
Type of Medium:
Online Resource
ISSN:
0027-8424
,
1091-6490
DOI:
10.1073/pnas.091114198
Language:
English
Publisher:
Proceedings of the National Academy of Sciences
Publication Date:
2001
detail.hit.zdb_id:
209104-5
detail.hit.zdb_id:
1461794-8
SSG:
11
SSG:
12
Permalink
