In:
Alzheimer's & Dementia: Translational Research & Clinical Interventions, Wiley, Vol. 4, No. 1 ( 2018-01), p. 224-233
Abstract:
This is the largest cohort ever to be used in the study of the morpho‐metabolic correlates of episodic memory in human, ensuring the validity of the obtained results. We found that encoding of information is linked to a posterior network previously evidenced to support working memory. The storage process was mainly supported in our study by medial temporal regions. Spontaneous retrieval of stimuli implicated broad neural networks including the frontal regions. These associations were particularly strong in APOE ε4 carriers suggesting that the free and selective reminding test is useful to detect Alzheimer's disease at an early stage.
Type of Medium:
Online Resource
ISSN:
2352-8737
,
2352-8737
DOI:
10.1016/j.trci.2018.03.010
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2832891-7
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