In:
European Journal of Organic Chemistry, Wiley, Vol. 2015, No. 1 ( 2015-01), p. 213-219
Abstract:
We report the synthesis of N ‐(α,β‐unsaturated acyl)‐substituted sulfonimidamides through a Pd‐catalyzed carbonylation protocol, employing sulfonimidamides as nucleophiles using CO gas released ex situ, and vinyl/aryl halides and triflates as reagents. The reaction is general and offers a unique class of products in moderate to good yields for a wide range of substrates and electrophiles; for example, aliphatic, aromatic (electron‐donating and ‐withdrawing groups), heteroaryl, vinyl halides, and triflates. We also expand our initial report on N ‐aryl–acyl‐substituted sulfonimidamide synthesis by employing aryltriflates as electrophiles. Furthermore, we report a surprisingly facile thermolytic Boc deprotection of N ‐(α,β‐unsaturated acyl) sulfonimidamides.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2015.1
DOI:
10.1002/ejoc.201403148
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
1475010-7
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