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  • 1
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2005
    In:  Epidemiology Vol. 16, No. 3 ( 2005-05), p. 311-316
    In: Epidemiology, Ovid Technologies (Wolters Kluwer Health), Vol. 16, No. 3 ( 2005-05), p. 311-316
    Type of Medium: Online Resource
    ISSN: 1044-3983
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2005
    detail.hit.zdb_id: 2042095-X
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  • 2
    In: European Journal of Epidemiology, Springer Science and Business Media LLC, Vol. 22, No. 3 ( 2007-03)
    Type of Medium: Online Resource
    ISSN: 0393-2990 , 1573-7284
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2007
    detail.hit.zdb_id: 2004992-4
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2011
    In:  The Cleft Palate-Craniofacial Journal Vol. 48, No. 5 ( 2011-09), p. 601-607
    In: The Cleft Palate-Craniofacial Journal, SAGE Publications, Vol. 48, No. 5 ( 2011-09), p. 601-607
    Abstract: The aim of this study was to compare reproduction patterns among Danish women born with isolated oral clefts versus the Danish background population. Design and Setting A nationwide population-based historic cohort study based on three registers: The Danish Facial Cleft Register, The Danish Civil Registration System, and the Fertility of Women and Couples Dataset. Participants Through linkages of the registers, the number of children and the exact age at childbirth of all Danish women born with an oral cleft from 1950 through 1988 (N = 1931) were obtained. These data were compared with similar data for the entire Danish female background population (N = 1,184,390). Results and Conclusions This study suggests that childlessness is higher among women born with an oral cleft (55%) than among women in the Danish background population (44%). Excluding women without children, women born with oral cleft had an average of 1.98 children per woman. This did not differ significantly from the background population (2.02 children/woman). Furthermore, the present study found that Danish women born with oral clefts on average were older (27.3 years of age) than the background population (24.7 years of age) when they had their first child (difference = 2.6 years, confidence interval = 2.41 to 2.80). Conclusion Danish women born with an oral cleft more often are childless or have their first child later, but if they have children, they tend to have as many children as other Danish women. Social, psychological, and biological reasons might be responsible for the reduced fertility.
    Type of Medium: Online Resource
    ISSN: 1055-6656 , 1545-1569
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2030056-6
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2005
    In:  The Cleft Palate-Craniofacial Journal Vol. 42, No. 3 ( 2005-05), p. 255-259
    In: The Cleft Palate-Craniofacial Journal, SAGE Publications, Vol. 42, No. 3 ( 2005-05), p. 255-259
    Abstract: The aim of this project was to assess whether any changes in the birth prevalence of cleft lip with/without cleft palate (CL[P]) occurred in Denmark during the period 1988 through 2001. In this period an official recommendation of a supplementation of folic acid to pregnant women was introduced; furthermore, smoking among pregnant women decreased considerably. Design and Settings There are few places in which ecological studies of oral clefts are possible. Denmark provides a particularly good setting for this kind of study because of a high ascertainment and a centralized registration of subjects with cleft over the last 65 years. Participants Cleft occurrence in Denmark from 1936 to 1987 has previously been reported. Here we extend the study to include all live-born children with oral clefts born in Denmark in 1988 through 2001. Among a total of 992,727 live births, 1332 children with CL(P) were born during this period. Results and Conclusions The birth prevalence of CL(P) in Denmark has previously been found to be constant in the period 1962 through 1987, with a frequency of 1.4 to 1.5 per 1000 live births. This study showed a similar occurrence in 1988 through 2001 (birth prevalence = 1.44 per 1000 live births, 95% confidence interval = 1.37 to 1.52). The introduction of folic acid and the decrease in smoking prevalence among pregnant women do not seem to have reduced the birth prevalence. This may be due to noncompliance with the folic acid recommendation and/or only a weak causal association between folic acid and smoking and occurrence of CL(P).
    Type of Medium: Online Resource
    ISSN: 1055-6656 , 1545-1569
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2030056-6
    Location Call Number Limitation Availability
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