In:
FEBS Letters, Wiley, Vol. 311, No. 3 ( 1992-10-26), p. 305-310
Abstract:
We have determined the full‐length cDNA sequence of the human αl(X) collagen gene by sequence analysis of a genomic clone ERG [(1991) Dev. Biol. 148, 562–572], and of cDNA fragments generated from a reverse transcribed as αl(X) mRNA by PCR. We defined the promoter region, the transcription initiation site and the full‐length 5′‐untranslated region. We also report the exon/intron boundaries of the transcript and the complete 3′‐untranslated region as well as a 3′‐flanking sequence containing two additional polyadenylation signals. The promoter region is homologous to chicken and mouse type X promoters within several highly conserved regions. The genomic organization shows high homologies to chicken and mouse.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(92)81126-7
Language:
English
Publisher:
Wiley
Publication Date:
1992
detail.hit.zdb_id:
1460391-3
SSG:
12
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