In:
Journal of Magnetic Resonance Imaging, Wiley, Vol. 30, No. 5 ( 2009-11), p. 956-966
Abstract:
To investigate the impact of interinstitutional variance (=interobserver variance between institutions) for volumetric and flow cardiac MR (CMR) data and if training on image reading could improve bias. Materials and Methods: In a three‐center study, a total of 32 adults with repaired Tetralogy of Fallot and 23 controls underwent CMR using standardized protocols for ventricular volumes/mass (by transverse and short‐axis cine‐MRI) and pulmonary/aortic blood flow by velocity‐encoded MRI (VEC‐MRI). Data were analyzed blinded and independently in each institution by experienced readers. Interinstitutional variance was determined before/after training on consented guidelines for image analysis. Results: In patients, initial interinstitutional variability of right ventricular parameters was substantial but decreased by training. On transverse planes, variation coefficient for end‐diastolic/systolic volumes and ejection fraction decreased from 22%, 19%, and 19% to 7%, 10%, and 8%, respectively ( P 〈 0.025). Left‐ventricular variation coefficients improved for end‐diastolic and stroke volumes from 8% and 15% to 4% and 6%, respectively ( P 〈 0.007). For short‐axis volumetry training resulted in narrowed limits of confidence. Variability did not significantly change in the controls. There was no significant difference between transverse/short‐axis MRI. Interinstitutional variance for VEC‐MRI in patients/controls was low ( 〈 4%). Conclusion: Interinstitutional variance is an important source of variability in volumetric but not in flow CMR. Such variance can be reduced effectively by consented training. J. Magn. Reson. Imaging 2009;30:956–966. © 2009 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
1053-1807
,
1522-2586
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
1497154-9
Permalink
