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  • 1
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2006
    In:  Pesquisa Veterinária Brasileira Vol. 26, No. 3 ( 2006-09), p. 139-146
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 26, No. 3 ( 2006-09), p. 139-146
    Abstract: Two outbreaks of poisoning by Tetrapterys multiglandulosa in cattle and the experimental reproduction of the toxicosis in sheep are described. Both outbreaks occurred on the same farm in the municipality of Bataiporã, state of Mato Grosso do Sul, Brazil. The first outbreak occurred in July-October 2004 and involved a cattle population at risk of 290 pregnant cows, which were introduced into a 60 hectare pasture with a legal reservation area heavily infested by T. multiglandulosa. Of these, 230 cows (79.3%) aborted, had stillbirths or delivered weak calves that died few days after birth. Seven cows died, and one cow and a 10-day-old calf were necropsied. The second outbreak occurred in September-October 2005, 40 days after 285 2-year-old heifers were introduced into the same pasture infested by T. multiglandulosa and where the first outbreak had occurred in the previous year. Nine heifers got sick and died, and three of then were necropsied. Clinical signs of affected cattle, including a 10-day-old calf, were marked lethargy, loss of weight with distension of the abdomen (ascites), subcutaneous dependant edema, distended and pulsating jugular veins, dyspnea and cardiac arrhythmia. Necropsy findings included a round and dilated heart with whitish and firm areas in the myocardium, and changes related to cardiac failure such as cavitary edema, nutmeg liver, pulmonary edema, a large blood clot in the left ventricle. Histopathological changes included necrosis and fibrosis in the myocardium, chronic passive hepatic centrolobular congestion, pulmonary edema, and spongy degeneration in the white matter of the brain. Experimental sheep died 29 (Sheep 1) and 35 (Sheep 2) days after being fed average daily doses of T. multiglandulosa corresponding to 14g/kg (Sheep 1) and 7,5 g/kg (Sheep 2) per day. Clinical signs were observed from the 7th day (Sheep1) and the 4th day (Sheep 2) of the experiment and included tachycardia, arrhythmia, lethargy and head pressing. Necropsy and histopathologic findings in both experimental sheep were very similar to those observed in affected cattle of the two spontaneous outbreaks.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2006
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  • 2
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    Online Resource
    FapUNIFESP (SciELO) ; 2009
    In:  Pesquisa Veterinária Brasileira Vol. 29, No. 3 ( 2009-03), p. 275-280
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 29, No. 3 ( 2009-03), p. 275-280
    Abstract: The necropsy reports of 335 horses necropsied at the LPV-UFSM between 1968-2007 were reviewed in order to determine the necropsy findings related with cause of death or reason for euthanasia. The distribution of these findings by organ system were as follows: digestive (79/335 [23.6%]), striated muscle and skeleton (47/335 [14.0%] ), nervous (37/335 [11.0%]), respiratory (35/335 [10.4%] ), integument (31/335 [9.3%]), hematopoietic (24/335 [7.2%] ), cardiovascular (13/335 [3.9%]), reproductive (12/335 [3.5%] ), urinary (7/335 [2.1%]), and endocrine (3/335 [0.9%] ). The cause of death was not possible to be determined in 47 (14.0%) necropsied horses. Displacements of the intestines (17/79 [21.5%]) were the main findings in digestive system, followed by obstruction and impactation (14/79 [17.7%] ). Torsion were the type of displacement more frequently observed in the intestines (14/17 [82.4%]). Among those the more prevalent affected the small intestine (7/14 [50%] ). Most horses dying from fractured bones were 1-5-year-old. The most prevalent diseases in the nervous system were leukoencephalo-malacia and trypanosomiasis, whereas respiratory depression due to anesthesia was the leading cause of death related to the respiratory system. Equine infectious anemia was the most diagnosed infectious disease and the main reason leading to euthanasia.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2009
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  • 3
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    Online Resource
    FapUNIFESP (SciELO) ; 2009
    In:  Pesquisa Veterinária Brasileira Vol. 29, No. 8 ( 2009-08), p. 643-652
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 29, No. 8 ( 2009-08), p. 643-652
    Abstract: The current study was performed to determine the pathology and distribution of lesions in the central nervous system (CNS) of 70 dogs naturally affected by canine distemper. Cases were grouped according to the age of the dogs and classified according to the evolution of the lesions. It was possibly to conclude that: (1) the encephalomyelitis induced by canine distemper virus is more prevalent in puppies and adults; (2) gross lesions in the CNS occur infrequently; (3) the brain is more frequently affected than the spinal cord; (4) the five anatomical sites of the rain more frequently affected are, in decreasing order of frequency, cerebellum, diencephalon, frontal lobe of telencephalon, pons and mesencephalon; (5) the anatomical site more frequently affected in the spinal cord is the cervical (C1-C5) segment; (6) subacute and chronic lesions are more common than acute ones; (7) demyelization is the more prevalent lesion and occur mainly in the cerebellum, pons and diencephalons, usually associated with astrogliosis and non-suppurative inflammation; (8) in most cases with astrogliosis, gemistocytic astrocytes are observed, frequently with syncitia formation; (9) non-suppurative leptomeningitis, malacia and cortical neuronal necrosis are moderately frequent in the brain and less so in the spinal cord; (10) inclusion bodies are frequent in the brain; occur mainly in astrocytes and less frequently in neurons, however independently of the affected cell they occur mainly in the nucleus; (11) a classification of canine distemper encephalitis based in age-related clinical syndromes it is not accurate.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2009
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  • 4
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2009
    In:  Pesquisa Veterinária Brasileira Vol. 29, No. 9 ( 2009-09), p. 713-718
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 29, No. 9 ( 2009-09), p. 713-718
    Abstract: Cases of congenital lymphedema were observed affecting 12 cross Red Angus calves from the central region of the state of Rio Grande do Sul, Brazil. Affected calves presented variable degrees of subcutaneous edema at birth, involving mainly the hind limbs but also other body regions. The injection of methylene blue dye in 5% solution into the interdigital space of the hind limbs of three affected calves and one normal control indicated an interruption of the lymph flow in the affected calves; this suggests a failure of the distal peripheral lymphatics to connect with the central trunks. At necropsy of three affected calves subcutaneous edema was variably observed in the hind limbs, prepuce and ventral abdomen. Edema of body cavities was not observed. In two cases there was hipoplasia of the popliteal lymph nodes associated to dilatation of lymphatic vessels. DNA tests demonstrated that all affected calves were born from cows sired by the same bull suggesting an inherited basis for the disease. Considering the small percentage of affected calves born from cows sired by the suspect bull it is probable that an autosomal recessive mode of inheritance is involved.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2009
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  • 5
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 28, No. 4 ( 2008-04), p. 223-230
    Abstract: The main objective of this study was to investigate the prevalence of diseases culminating with death or motivating euthanasia of dogs from the midland region of the Midwest of Rio Grande do Sul State, Brazil. The necropsy files of the Laboratório de Patologia Veterinária (LPV) of the Universidade Federal de Santa Maria (UFSM) were accessed and necropsy protocols of dogs necropsied between January 1965 and December 2004 were reviewed. During this period 4,844 reports of canine necropsies were filed at the LPV-UFSM. The case distribution in relation to the disease categories diagnosed was as follows: infectious and parasitic diseases (1,693 [35.0%]); neoplasms (378 [7.8%] ); disorders caused by physical agents (369 [7.6%]); degenerative diseases (342 [7.1%] ); poisonings and toxinfections (112 [2.3%]); euthanasia due to convenience (101 [2.1%] ); metabolic and endocrinological diseases (97 [2.0%]); iatrogenic disorders (83 [1.7%] ); developmental disorders (25 [0.5%]); immune mediate diseases (10 [0.2%] ); and nutritional disorders (6 [0.1%]). Other disorders, including multifactorial or idiopathic diseases contributed 80 (1.6%) cases. In 1,548 (32.0%) out of the 4,844 cases it was not possible to establish either cause of death or reason for euthanasia. Infectious and parasitic diseases (mainly canine distemper, parvoviral enteritis and intestinal parasitism), neoplasia (mainly mammary neoplasms and lymphoma), disorders caused by physical agents (mainly accidents caused by automotive vehicles) and degenerative diseases (mainly chronic renal failure, cirrhosis, and congestive heart failure) were the main disease categories causing death or motivating euthanasia in dogs of this midland region. However, when cases were evaluated in relation with the age of the dog, the disease prevalence differed. The main causes of death in puppies were infectious and parasitic disease (mainly parvoviral enteritis, canine distemper, and intestinal parasitism). In adult dogs the most important causes of death were canine distemper, neoplasia and trauma. In age dogs, approximately half of the deaths could be attributed to neoplasia and degenerative disease.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2008
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  • 6
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2015
    In:  Pesquisa Veterinária Brasileira Vol. 35, No. 6 ( 2015-06), p. 541-546
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 35, No. 6 ( 2015-06), p. 541-546
    Abstract: Abstract: Neoplasms in swine are rare. This paper describes neoplasms found in swine in the diagnostic routine of a veterinary pathology laboratory in the Central Region of Rio Grande do Sul, Brazil during a 49-year period, during which 2,266 cases of the various affections in swine were diagnosed. Of those 37 cases (1.6%) were neoplasms. In decreasing order of prevalence, the following neoplasms were found: lymphoma (11 out of 37 cases), nephroblastoma (11/37), melanoma (8/37), and papilloma (2/37). Adenoma hepatocelular, carcinoma hepatocelular, cholangiocarcinoma, malignant fibrous histiocytoma, granulocytic sarcoma were each found in one case out of the 37 cases. The gross and histological aspects of these tumors are described and their epidemiology is compared with the data available in the literature for neoplasia in swine.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2015
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  • 7
    In: Anaerobe, Elsevier BV, Vol. 55 ( 2019-02), p. 103-106
    Type of Medium: Online Resource
    ISSN: 1075-9964
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
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  • 8
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2013
    In:  Pesquisa Veterinária Brasileira Vol. 33, No. 10 ( 2013-10), p. 1208-1214
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 33, No. 10 ( 2013-10), p. 1208-1214
    Abstract: A retrospective study of all necropsy performed in pigs in the Laboratório de Patologia Veterinária (LPV) at Universidade Federal de Santa Maria (UFSM) was carried out in order to determine the characteristics and frequency of diseases in the swine population raised in the region the region covered by the activities of LPV. Five hundred and four cases with conclusive diagnosis were found. The type of pig-raising in the area is mainly a familiar enterprise and the diseases found in this survey reflect this reality Infectious and parasitic diseases were the most prevalent [380(68.1%)], followed, in descending order of frequency, by nutritional and metabolic diseases [64(11.5%)] , poisonings and toxi-infections and development disorders [15(2.7%)]. Other disorders due to varying etiologies, especially trauma, were cause of death in just over 11% of the cases. Bacterial diseases were responsible for more than half of the causes of death in pigs of the studied population, pointing to the influence of management, environmental and nutritional regional husbandry. The moist frequent disease diagnosed in pigs in the region in the region covered by the study was edema disease which along with other forms of infection by Escherichia coli was responsible for 23% of deaths. Viral diseases and neoplasm were not major causes of death in pigs in the region studied. Nutritional hepatosis and aflatoxicosis are important diseases in pigs in this region and and there causation are mainly linked to nutritional management.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2013
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  • 9
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 27, No. 7 ( 2007-07), p. 261-268
    Abstract: From 1990 to 2005, tissues from 2,912 cattle necropsies were examined at the Laboratory of Veterinary Pathology (LPV) of the Federal University of Santa Maria (UFSM), Brazil. These tissues came from necropsies performed by faculty members of the LPV or were mailed-in samples from necropsy performed by veterinarian practitioners. In 461 (15.83%) of these necropsies the cause of death was attributed to the ingestion of poisonous plants. In decreasing order of frequency poisoning by the following plants were registered: Senecio spp (56.14%), Pteridium aquilinum (12.06%), Ateleia glazioviana (10.31%), Solanum fastigiatum (5.04%), Baccharis coridifolia (3.29%), Xanthium cavanillesii (3.07%), Senna occidentalis (2.63%), Ramaria flavo-brunnescens (2.41%), Amaranthus spp (2.19%), Vicia villosa (1.54%), Ipomoea batatas, Prunus sellowii, cytrus pulp (0.44% each), Cestrum parqui, Claviceps paspali, Claviceps purpurea, Brachiaria spp and Lantana sp (0.22% each). In a given outbreak the number of affected cattle was substantially higher than the number of necropsies performed. The following aspects are discussed for each plant: geographical distribution; factors inducing ingestion; morbidity, mortality and lethality rates, clinical signs, necropsy findings, histopathology. For those plants in which information on the active principle and pathogenesis are available, these aspects are included in the discussion.
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2007
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  • 10
    Online Resource
    Online Resource
    FapUNIFESP (SciELO) ; 2007
    In:  Pesquisa Veterinária Brasileira Vol. 27, No. 11 ( 2007-11), p. 471-480
    In: Pesquisa Veterinária Brasileira, FapUNIFESP (SciELO), Vol. 27, No. 11 ( 2007-11), p. 471-480
    Abstract: A retrospective study in 80 cases of canine hepatic cirrhosis was carried out at the Veterinary Pathology Laboratory of the Federal University of Santa Maria, Rio Grande do Sul, Brazil. Considering those cases in which the sex and age of the dogs were informed in the necropsy reports, males comprised 53.8% of the cases and 46.2% were females; while 50.0% of these dogs were aged, 48.6% were adults and 1.4% were puppies. The main observed clinical signs include ascites (39/80 [48.8%]), icterus (19/80 [23.8%] ), anorexia (13/80 [16.2%]), neurological disturbances (12/80 [15.0%] ), dyspnea (12/80 [15.0%]) and subcutaneous edema (10/80 [12.5%] ). In 63 dogs for which there was a description of gross morphology in the necropsy reports, 76.2% had macronodular and 23.8% had micronodular cirrhosis. In 14 cases in which the histopathology of the liver was reviewed different degrees of fibrosis were observed: mild in 57.2%, moderate in 21.4%, or marked in 21.4%; in these cases there were no correlation with the degree of fibrosis and other associated histological changes such as lipidosis, biliary ducts hyperplasia, inflammation, bilestasis, hemosiderosis and random hepatocellular necrosis. Extra hepatic changes included ascites (39/63 [61.9%]), icterus (19/63 [30.2%] ), status spongiosus (15/63 [23.8%]), hydrothorax (12/63 [19.0%] ), subcutaneous edema (10/63 [15.9%]), portosystemic shunts (11/63 [17.5%] ), gastric our duodenal ulceration (11/63 [17.5%]) and cholemic nephrosis (4/63 [6.3%] ).
    Type of Medium: Online Resource
    ISSN: 0100-736X
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2007
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