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Discovery and Evaluation of N-Cyclopropyl-2, 4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)benzamide (BMS-605541), a Selective and Orally Efficacious Inhibitor of Vascular Endothelial Growth Factor Receptor-2

Borzilleri, Robert M. ; Bhide, Rajeev S. ; Barrish, Joel C. ; [et al.]

American Chemical Society (ACS) ; 2006

In: Journal of Medicinal Chemistry Vol. 49, No. 13 ( 2006-06-01), p. 3766-3769

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In: Journal of Medicinal Chemistry, American Chemical Society (ACS), Vol. 49, No. 13 ( 2006-06-01), p. 3766-3769

Type of Medium: Online Resource

ISSN: 0022-2623 , 1520-4804

URL: Article

DOI: 10.1021/jm060347y

DOI: 10.1021/jm060347y.s001

Language: English

Publisher: American Chemical Society (ACS)

Publication Date: 2006

detail.hit.zdb_id: 1491411-6

SSG: 15,3

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Design, Synthesis, and Evaluation of Orally Active 4-(2, 4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2, 1-f][1, 2, 4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors

Borzilleri, Robert M. ; Zheng, Xiaoping ; Qian, Ligang ; [et al.]

American Chemical Society (ACS) ; 2005

In: Journal of Medicinal Chemistry Vol. 48, No. 12 ( 2005-06-01), p. 3991-4008

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In: Journal of Medicinal Chemistry, American Chemical Society (ACS), Vol. 48, No. 12 ( 2005-06-01), p. 3991-4008

Type of Medium: Online Resource

ISSN: 0022-2623 , 1520-4804

URL: Article

DOI: 10.1021/jm0501275

DOI: 10.1021/jm0501275.s001

Language: English

Publisher: American Chemical Society (ACS)

Publication Date: 2005

detail.hit.zdb_id: 1491411-6

SSG: 15,3

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Discovery of Brivanib Alaninate (( S )-(( R )-1-(4-(4-Fluoro-2-methyl-1 H -indol-5-yloxy)-5-methylpyrrolo[2,1- f ][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)

Cai, Zhen-wei ; Zhang, Yongzheng ; Borzilleri, Robert M. ; [et al.]

American Chemical Society (ACS) ; 2008

In: Journal of Medicinal Chemistry Vol. 51, No. 6 ( 2008-03-01), p. 1976-1980

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In: Journal of Medicinal Chemistry, American Chemical Society (ACS), Vol. 51, No. 6 ( 2008-03-01), p. 1976-1980

Type of Medium: Online Resource

ISSN: 0022-2623 , 1520-4804

URL: Article

DOI: 10.1021/jm7013309

Language: English

Publisher: American Chemical Society (ACS)

Publication Date: 2008

detail.hit.zdb_id: 1491411-6

SSG: 15,3

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