In:
Journal of the Peripheral Nervous System, Wiley, Vol. 21, No. 2 ( 2016-06), p. 105-110
Abstract:
The aim of the study was to analyze specific features of Guillain‐Barré syndrome ( GBS ) in old people. The study included 403 GBS patients (62% young [ 〈 60 years], 35% young‐old [60–80 years] , and 3% old‐old [ 〉 80 years]). Diagnosis of GBS was made according to the National Institute of Neurological Disorders and Stroke (NINDS criteria). Severe disability ( GBS disability score of 〉 3) at nadir was more common in old compared with young patients (p = 0.0001) as was mortality (9% vs. 2%, respectively). Acute motor and sensory axonal neuropathy and hyponatremia were more common in old compared with young patients (12% vs. 6% and 27% vs. 18%, respectively, p = 0.04). A positive history for malignancy was more than three times more common in old than young patients (11% vs. 3%, respectively, p = 0.01). Disability on nadir was similar in young‐old and old‐old subjects with disability on discharge being more severe in old‐old (p = 0.04) suggesting slower recovery in this subgroup. Bulbar symptoms were more common in old‐old compared with young‐old (50% vs. 19%, respectively, p = 0.01). Comorbidities were present in virtually all old‐old patients compared with 66% of young‐old patients (p = 0.04). In conclusion, Elderly patients, and especially old‐old patients, with GBS have more severe disease with slower recovery than do younger patients.
Type of Medium:
Online Resource
ISSN:
1085-9489
,
1529-8027
DOI:
10.1111/jns.2016.21.issue-2
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2030613-1
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