In:
Journal of the American Oil Chemists' Society, Wiley, Vol. 36, No. 8 ( 1959-08), p. 322-325
Abstract:
Effects of medium‐chain (C 6 –C 12 ) saturated triglycerides (MCT) and long‐chain (C 14 –C 18 ) saturated triglycerides (LCT) with and without linoleic acid (LA) supplementation were studied on rats fed purified diets With 2% linoleic acid rats fed MCT and LCT grew somewhat better than those on a low‐fat diet with the same supplement. Without linoleic acid those fed MCT grew better, and those fed LCT grew worse than those on the corresponding low‐fat diet. MCT seemed to decrease, and LCT to increase linoleic acid requirements. In survival studies 14 out of 18 rats fed 20% MCT were alive after 2 years; of their controls fed 20% lard, 10 out of 19 survived. Reproduction studies in females gave equally poor results on unsupplemented low‐fat, MCT, and LCT diets regarding implantation, birth weight, and survival rate. The weaning weights of the young on MCT were however the highest. With 2% LA weaning weights were equally high with LCT and MCT but lower with low‐fat diet. In animals fed low‐fat diets not supplemented with LA, low serum cholesterol was associated with high liver cholesterol. With MCT, serum values were higher and liver values were significantly lower. With unsupplemented LCT, serum and liver values were high. When the three diets were supplemented with 2% LA, there were no longer any differences in the serum levels and in the liver levels. Whether ar not the presence of some oleate in the MCT and LCT influenced the cholesterol results is not certain. The differences in the effects of MCT and LCT are discussed.
Type of Medium:
Online Resource
ISSN:
0003-021X
,
1558-9331
Language:
English
Publisher:
Wiley
Publication Date:
1959
detail.hit.zdb_id:
2041388-9
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