In:
The American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, Vol. 105, No. 1 ( 2021-07-07), p. 217-221
Abstract:
Rickets is an often-neglected, painful, and disabling childhood condition of impaired bone mineralization. In this case series we describe a cluster of 29 children with severe, painful bone deformities who live in the very remote region of Nagaland in northwest Myanmar. Children were found to have low 25-hydroxyvitamin D, elevated parathyroid hormone, and elevated alkaline phosphatase levels, consistent with nutritional rickets secondary to vitamin D deficiency, calcium deficiency, or a combination of the two. After treatment with vitamin D 3 and calcium carbonate, significant improvement was seen in symptoms, biochemistry, and radiography. This is the first report of nutritional rickets in Myanmar in more than 120 years. Vitamin D and calcium supplementation, and food fortification for pregnant women and young children may be required to prevent this potentially devastating disease.
Type of Medium:
Online Resource
ISSN:
0002-9637
,
1476-1645
DOI:
10.4269/ajtmh.20-1431
Language:
Unknown
Publisher:
American Society of Tropical Medicine and Hygiene
Publication Date:
2021
detail.hit.zdb_id:
1491674-5
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