In:
FEBS Open Bio, Wiley, Vol. 3, No. 1 ( 2013-01), p. 459-466
Abstract:
A1254, a polychlorinated biphenyls mixture, exerts neurotoxic effects in C6 glial cells. Sub‐toxic concentrations of A1254 decrease levels of glial fibrillary acidic protein. Sub‐toxic concentrations of A1254 inhibit cAMP‐induced astrocytic differentiation. A1254 reduces cAMP‐dependent phosphorylation of STAT3 on Ser727 via protein kinase C. Polychlorinated biphenyls may affect astrocytic differentiation of glial cells.
Type of Medium:
Online Resource
ISSN:
2211-5463
,
2211-5463
DOI:
10.1016/j.fob.2013.10.008
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
2651702-4
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