In:
Journal of the Intensive Care Society, SAGE Publications, Vol. 20, No. 1 ( 2019-02), p. 86-89
Abstract:
A 79-year-old critically ill woman presented with remarkable prolongation of activated partial thromboplastin time and thrombin time combined with high levels of anti-factor IIa activity 26 days after coronary artery bypass grafting. Coagulation disorder was associated with severe bleeding. Cause of coagulopathy was accidental administration of argatroban in an unknown dosage. Clearance of argatroban was significantly prolonged because of a liver function disorder related to septic multiorgan failure. Argatroban reversal was performed with prothrombin complex concentrate.
Type of Medium:
Online Resource
ISSN:
1751-1437
DOI:
10.1177/1751143718761847
Language:
English
Publisher:
SAGE Publications
Publication Date:
2019
detail.hit.zdb_id:
2701626-2
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