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  • Ovid Technologies (Wolters Kluwer Health)  (2)
  • Aminorroaya, Arya  (2)
  • 2020-2024  (2)
  • 1
    In: Journal of the American Heart Association, Ovid Technologies (Wolters Kluwer Health), Vol. 11, No. 13 ( 2022-07-05)
    Abstract: Rheumatic heart disease (RHD) takes a heavy toll in low‐ and middle‐income countries. We aimed to present worldwide estimates for the burden of the RHD during 1990 to 2019 using the GBD (Global Burden of Disease) study. Methods and Results Sociodemographic index (SDI) and age‐period‐cohort analysis were used to assess inequity. The age‐standardized death, disability‐adjusted life years, incidence, and prevalence rates of RHD were 3.9 (95% uncertainty interval, 3.3–4.3), 132.9 (95% uncertainty interval, 115.0–150.3), 37.4 (28.6–46.7), and 513.7 (405.0–636.3) per 100 000 in 2019, respectively. The age‐standardized incidence and prevalence rates increased by 14.4% and 13.8%, respectively. However, disability‐adjusted life years and death rates decreased by 53.1% and 56.9%, respectively. South Asia superregion had the highest age‐standardized disability‐adjusted life years and deaths. Sub‐Saharan Africa had the highest age‐standardized incidence and prevalence rates. There was a steep decline in RHD burden among higher‐SDI countries. However, only age‐standardized deaths and disability‐adjusted life years rates decreased in lower‐SDI countries. The age‐standardized years of life lost and years lived with disability rates for RHD significantly declined as countries' SDI increased. The coefficients of birth cohort effect on the incidence of RHD showed an increasing trend from 1960 to 1964 to 2015 to 2019; however, the birth cohort effect on deaths attributable to RHD showed unfailingly decreasing trends from 1910 to 1914 to 2015 to 2019. Conclusions There was a divergence in the burden of RHD among countries based on SDI levels, which calls for including RHD in global assistance and funding. Indeed, many countries are still dealing with an unfinished infectious disease agenda, and there is an urgency to act now to prevent an increase in future RHD burden.
    Type of Medium: Online Resource
    ISSN: 2047-9980
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2653953-6
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  • 2
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 142, No. Suppl_3 ( 2020-11-17)
    Abstract: Introduction: Afib has a drastically higher incidence and burden among elderly. Aside from cardio and cerebrovascular outcomes in these patients, Afib individually brings about a significant mortality among elderly. Scoring systems like CHA2DS2-VASc imply that female gender, advanced age, and comorbidities augment the morbidity of Afib. Hypothesis: This study aims to evaluate the global and national discrepancies in Afib quality of care (QoC) within a 38-year time among over 70-year-old population. Methods: Four key epidemiologic indices were measured using the data from the estimates of ‘Global Burden of Diseases’ study, 2017: Mortality to incidence, DALY to prevalence, YLL to YLD, and Prevalence to Incidence ratio. Principal Component Analysis was utilized to find the highest value of all eigenvectors of the 4 estimates. The adaptive component derived from this analysis was set as the QoC index (QCI), a centile-based score reflecting better QoC with inclining values. Statistical analyses were done by R software v3.6.1. Results: QCI score decreased globally in over 70-year-old population of both females (-4.61%), and males (-3.92%). The gender disparity increased in favor of higher scores for males (-0.50 in 1990, -1.19 in 2017). At the country level, majority of nations had decreased QCI within this period (Figure 1). The US had the second highest QCI in over 70-year-old population (98.30), as well as 80-84 (98.24) and 85-89 years (98.07), specifically. Although the QCI dropped 2.18 scores from 1990 to 2017, the female-male disparity decreased in age group of over 70 (4.15 to 3.44) in US. Conclusions: Predominant world-wide decline in QCI, could imply the decreased quality of care for patients with Afib. Observed gender-specific discrepancy in a disease with female-dominant morbidity calls for the necessity to adapt health policies accordingly. However, further studies with adjustment for concomitant risk factors are required to address the underlying causes.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 1466401-X
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