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  • 1
    Online Resource
    Online Resource
    New York, NY :Springer,
    Keywords: Sustainable biodiversity. ; Electronic books.
    Description / Table of Contents: Building on important themes that emerged from the 5th international canopy conference, this book summarizes the issue of "treetops at risk" and assembles a global authorship to examine past accomplishments and future initiatives critical in forest conservation.
    Type of Medium: Online Resource
    Pages: 1 online resource (436 pages)
    Edition: 1st ed.
    ISBN: 9781461471615
    Language: English
    Note: Intro -- Foreword -- Contents -- Contributors -- Part I: Emerging Issues -- Chapter 1: The Role of Scientific Conferences to Foster Conservation Solutions for Global Forests -- Chapter 2: Greening the Planet? -- Chapter 3: Comparative Canopy Biology and the Structure of Ecosystems -- 1 Summary -- 2 Seeing the Forest for the Herbs -- 3 More to Pond Scum than Meets the Eye -- 4 The Geometry of Canopy Biology -- 5 Getting to the Root of the Matter -- 6 Conclusions Vis-à-vis Biodiversity -- References -- Chapter 4: Forest Canopies as Earth's Support Systems: Priorities for Research and Conservation -- 1 Forest Canopies: Real or Imagined? -- 1.1 Trees and Forest Structure -- 1.2 Forest Canopy as a Physical System -- 1.3 Other Organismal Groups -- 1.4 Forest Ecological Interactions: Are They Vertically Segregated? -- 1.5 How Meaningful Is the Concept of Stratification? -- 2 Human Disturbance and Forest Canopies -- 2.1 Canopy Ecosystem Services -- 2.2 Climate Change in the Canopy -- 2.3 Canopies and Carbon Budgets -- 3 Toward an Integrated Science of Canopy and Tropical Forest Ecosystems -- 4 Need for Building Human Capacity -- References -- Chapter 5: Emerging Threats to Tropical Forests -- 1 Introduction -- 2 Increasing Globalization and Industrialization -- 3 Road and Highway Expansion -- 4 China's Role in Illegal Logging -- 5 Expansion of Biofuels -- 6 Human Population Growth -- 7 Emerging Pathogens -- 8 Climatic and Atmospheric Changes -- 9 Environmental Synergisms -- 10 Conclusion -- References -- Chapter 6: Rethinking the Role of Tropical Forest Science in Forest Conservation and Management -- 1 Introduction -- 2 Methods -- 3 Results: Publication Trends -- 3.1 Scientific Publications and Deforestation -- 4 Discussion -- References -- Chapter 7: REDD: How Can Scientists Change the Political Jungle? -- 1 Explanatory Box -- 1.1 Community MRV. , Chapter 8: Narrowing Global Species Estimates -- 1 Introduction -- 2 Recent New Estimates of Global Species Richness -- 3 Extrapolating from Local to Global Species Richness -- 4 Is the Forest Canopy the Last Biotic Frontier? -- References -- Part II: Climate Change -- Chapter 9: Tropical Cyclones and Forest Dynamics Under a Changing Climate: What Are the Long- Term Implications for Tropical Forest Canopies in the Cyclone Belt? -- 1 Introduction -- 2 Tropical Cyclones -- 2.1 Tropical Cyclones and Tropical Moist Forests -- 2.1.1 Landscape and Local-Scale Patterns and Processes -- 2.1.2 Ecological Effects -- 3 Likely Effects of Climate Change on Tropical Cyclones and Tropical Forests -- References -- Chapter 10: Canopies and Climate Change -- Bullet Points -- 1 Introduction -- 1.1 Tree Responses to Elevated Temperature and CO 2 -- 2 Canopy Invertebrates and Climate Change -- 2.1 Pollination -- 2.1.1 Herbivory -- 3 Complexity and Future Questions -- References -- Chapter 11: Church Forest Status and Carbon Sequestration in Northern Ethiopia -- 1 Introduction -- 2 Results -- References -- Chapter 12: A Novel Approach to Simulate Climate Change Impacts on Vascular Epiphytes: Case Study in Taiwan -- 1 Epiphytes in a Changing World -- 2 Epiphyte Distribution Modeling -- 3 Methods -- 3.1 Data Preparation -- 3.2 Model Building -- 3.3 Species Richness Map -- 4 Results, Applications, and Prospects -- References -- Chapter 13: Sensitivity and Threat in High-Elevation Rainforests: Outcomes and Consequences of the IBISCA-Queensland Project -- 1 Introduction -- 2 The Uniqueness of the High-Elevation Forests: Results from Disparate Taxa -- 3 Endemism and Options: Conservation Implications for a High-Elevation Specialist -- 4 Future Work and Conservation Options -- References. , Chapter 14: A Mature Forest Canopy in a CO 2 -Rich Future: An Experiment at the Swiss Canopy Crane Research Site -- References -- Chapter 15: Shock Value: Are Lianas Natural Lightning Rods? -- 1 Introduction -- 1.1 Lightning Basics -- 1.2 Lightning (Sometimes) Kills Trees -- 1.3 Lightning (Always) Kills Lianas -- 1.4 Lianas (Maybe) Protect Trees -- 1.5 Electrical Properties of Lianas Versus Trees -- 2 Research Needs -- References -- Chapter 16: Potential Impacts of Global Changes on Epiphytic Bryophytes in Subtropical Montane Moist Evergreen Broad-Leaved Forests, SW China -- 1 Introduction -- 2 Potential Impacts of Forest Degradation on Epiphytic Bryophytes -- 3 Potential Impacts of Climate Change on Epiphytic Bryophytes -- 4 Potential Impacts of Atmospheric N Pollution on Epiphytic Bryophytes -- 5 Conclusions -- References -- Chapter 17: "Canopy-Less" Monitoring of Biodiversity and Climate Change: Signs of a Leaky Roof -- 1 Introduction -- 2 "The Third Dimension" -- 3 Climate Change and Canopy Monitoring -- 4 Passive Techniques for Biodiversity Monitoring -- 5 Conclusions -- References -- Part III: New Approaches -- Chapter 18: Mesoscale Exploration and Conservation of Tropical Canopies in a Changing Climate -- 1 Introduction -- 2 Observing Changes in Forest Canopies -- 3 Evolution of the Carnegie Airborne Observatory -- 4 Touring Canopies with the CAO -- 5 CAO Applications for Science and Conservation -- 6 The Future of Mesoscale Canopy Science -- References -- Chapter 19: Why Do Sloths Poop on the Ground? -- References -- Chapter 20: Birds of the "Canopy": Historical Perspective, Current Trends, and Future Directions -- 1 Why Canopy? -- 2 Do Canopies Host a Unique Set of Species? -- 3 Methods to Study Canopy Birds -- 3.1 Mist Netting -- 3.2 Towers, Platforms, and Cranes -- 4 Trends in Canopy Bird Research -- 5 Implications for Conservation. , References -- Chapter 21: Functional Roles of Lianas for Forest Canopy Animals -- 1 Introduction -- 2 Functional Roles of Lianas -- 2.1 Lianas as Food -- 2.2 Lianas as Structure -- 2.3 Lianas and Canopy Ants -- 3 Conclusions -- References -- Chapter 22: Islands in a Sea of Foliage: Mistletoes as Discrete Components of Forest Canopies -- 1 Introduction -- 2 Diversity of Invertebrates on Mistletoes -- 2.1 Specialists: Psyllids -- 2.2 Generalists: Spiders -- 3 Indicators of Forest Health: Butterflies, Moths, and Mistletoes -- References -- Chapter 23: Nonvascular Epiphytes: Functions and Risks at the Tree Canopy -- 1 Research on Nonvascular Epiphytes -- 2 The "Biosphere Tower": A Novel Canopy Access for Long-Term Research on Microbes and Nonvascular Epiphytes -- 3 Mechanisms and Functions of Nonvascular Epiphytes -- 4 Risks of Land-Use Change and Global Warming -- 5 Conclusion -- References -- Chapter 24: Canopy Texture Analysis for Large-Scale Assessments of Tropical Forest Stand Structure and Biomass -- 1 Introduction -- 2 Methodological Background and Rationale -- 3 Results from Some Case Studies -- 4 Limits and Perspectives -- References -- Chapter 25: Changing Tropical Forest Dynamics and Their Effects on Canopy Geometry and Tropical Forest Biodiversity -- 1 Introduction -- 2 Observed Changes Within Tropical Forests -- 3 The Potential Drivers of Changing Tropical Forest Dynamics -- 4 Effects of Changes in the Physical Structure of Tropical Forest Canopies on Biodiversity -- 5 Conclusions -- References -- Chapter 26: Reproductive Biology and Population Genetics of Some Canopy- and Understorey-Dominant Tree Species of Sri Lanka: Implications for Conservation Management in a Fragmented Landscape -- 1 Introduction -- 2 Reproductive Phenology -- 3 Pollination Ecology -- 4 Breeding Systems -- 5 Mating Systems -- 6 Genetic Diversity. , 7 Discussions and Conclusions -- References -- Chapter 27: The Importance of Flowers for Beetle Biodiversity and Abundance -- 1 Introduction -- 2 Methods -- 2.1 Study Site -- 2.2 Sampling -- 2.3 Microhabitat Biomass Estimation -- 3 Results -- 4 Discussion -- References -- Chapter 28: Assessing Canopy Processes at Large Landscape Scales in the Western Ghats Using Remote Sensing -- 1 Introduction -- 2 Conclusion -- References -- Chapter 29: Ontogeny of Herbivory on Leaves in a Tropical Rain Forest in Madagascar -- 1 Introduction -- 2 The Study Area -- 3 Materials and Methods -- 3.1 Damage by Various Agents to Hardened, Mature Leaves of Different Relative Ages -- 3.2 Damage to Recently Flushed Versus Mature Foliage by Grazing and Skeletonizing Insects -- 3.3 Weekly Rate of Damage to Newly Flushed Leaves -- 4 Results -- 4.1 Damage by Various Agents to Hardened, Mature Leaves of Different Relative Ages -- 4.2 Damage to Recently Flushed Versus Mature Foliage by Grazing and Skeletonizing Insects -- 4.3 Weekly Rate of Damage to Newly Flushed Leaves -- 5 Discussion -- References -- Chapter 30: Do Water Bears Climb Trees Too? -- 1 Introduction -- 2 Results -- 3 Discussion -- References -- Chapter 31: From Leaf Litter to Canopy: Noninvasive and Reliable Sampling in a Tropical Rainforest -- 1 Introduction -- 2 Study Site -- 3 Methods and Results -- 3.1 Forest Structure -- 3.2 Microhabitat Selection -- 3.3 Biodiversity Estimation and Monitoring -- 3.4 Horizontal Movement Through the Canopy -- 4 Discussion -- References -- Part IV: Education and Outreach -- Chapter 32: Win-Win for Scientists and Citizen Scientists Who Engage in Amazon Canopy Expeditions -- 1 Introduction -- 2 Experiencing Biodiversity -- 3 Research and Conservation -- 4 Cultural Immersion -- 5 Global Perspective -- References. , Chapter 33: In the Canopy with Wheelchairs: A Model for Teaching Field Biology.
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  • 2
    Publication Date: 2013-02-27
    Description: Prostaglandin E2 is now widely recognized to play critical roles in brain inflammation and injury, although the responsible prostaglandin receptors have not been fully identified. We developed a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2, TG6-10-1, with a sufficient pharmacokinetic profile to be used in vivo....
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 2014-08-02
    Description: Article Previous studies have shown that repeated tool use results in extension of body representation. Ganesh et al . now show that in addition to extension of body representation, tool use is also accompanied by an immediate shortening of perceived arm length on a trial-by-trial basis. Nature Communications doi: 10.1038/ncomms5524 Authors: G. Ganesh, T. Yoshioka, R. Osu, T. Ikegami
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2012-02-22
    Description: With interest waning in the use of cyclooxygenase-2 (COX-2) inhibitors for inflammatory disease, prostaglandin receptors provide alternative targets for the treatment of COX-2–mediated pathological conditions in both the periphery and the central nervous system. Activation of prostaglandin E2 receptor (PGE2) subtype EP2 promotes inflammation and is just beginning to be explored as a therapeutic target. To better understand physiological and pathological functions of the prostaglandin EP2 receptor, we developed a suite of small molecules with a 3-aryl-acrylamide scaffold as selective EP2 antagonists. The 12 most potent compounds displayed competitive antagonism of the human EP2 receptor with KB 2–20 nM in Schild regression analysis and 268- to 4,730-fold selectivity over the prostaglandin EP4 receptor. A brain-permeant compound completely suppressed the up-regulation of COX-2 mRNA in rat cultured microglia by EP2 activation and significantly reduced neuronal injury in hippocampus when administered in mice beginning 1 h after termination of pilocarpine-induced status epilepticus. The salutary actions of this novel group of antagonists raise the possibility that selective block of EP2 signaling via small molecules can be an innovative therapeutic strategy for inflammation-related brain injury.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 5
    Publication Date: 2014-06-07
    Description: Recent progress characterizing the reaction mechanism(s) of fluorescent probes with reactive oxygen species has made it possible to rigorously analyze these reactive species in biological systems. We have developed rapid high throughput-compatible assays for monitoring cellular production of superoxide radical anion and hydrogen peroxide using hydropropidine and coumarin boronic acid probes, respectively. Coupling plate reader-based fluorescence measurements with HPLC-based simultaneous monitoring of superoxide radical anion and hydrogen peroxide provides the basis for the screening protocol for NADPH oxidase (Nox) inhibitors. Using this newly developed approach along with the medium-throughput plate reader-based oximetry and EPR spin trapping as confirmatory assays, it is now eminently feasible to rapidly and reliably identify Nox enzyme inhibitors with a markedly lower rate of false positives. These methodological advances provide an opportunity to discover selective inhibitors of Nox isozymes, through enhanced conceptual understanding of their basic mechanisms of action.
    Print ISSN: 0021-9258
    Electronic ISSN: 1083-351X
    Topics: Biology , Chemistry and Pharmacology
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  • 6
    Publication Date: 2015-06-11
    Description: The timely resolution of inflammation prevents continued tissue damage after an initial insult. In the brain, the death of activated microglia by apoptosis has been proposed as one mechanism to resolve brain inflammation. How microglial death is regulated after activation is still unclear. We reported that exposure to lipopolysaccharide (LPS) and interleukin (IL)-13 together initially activates and then kills rat microglia in culture by a mechanism dependent on cyclooxygenase-2 (COX-2). We show here that activation of the E prostanoid receptor 2 (EP2, PTGER2) for prostaglandin E 2 mediates microglial death induced by LPS/IL-13, and that EP2 activation by agonist alone kills microglia. Both EP2 antagonists and reactive oxygen scavengers block microglial death induced by either LPS/IL-13 or EP2 activation. By contrast, the homeostatic induction of heme oxygenase 1 (Hmox1) by LPS/IL-13 or EP2 activation protects microglia. Both the Hmox1 inducer cobalt protoporphyrin and a compound that releases the Hmox1 product carbon monoxide (CO) attenuated microglial death produced by LPS/IL-13. Whereas CO reduced COX-2 protein expression, EP2 activation increased Hmox1 and COX-2 expression at both the mRNA and protein level. Interestingly, caspase-1 inhibition prevented microglial death induced by either LPS/IL-13 or low (but not high) concentrations of butaprost, suggestive of a predominantly pyroptotic mode of death. Butaprost also caused the expression of activated caspase-3 in microglia, pointing to apoptosis. These results indicate that EP2 activation, which initially promotes microglial activation, later causes delayed death of activated microglia, potentially contributing to the resolution phase of neuroinflammation.
    Print ISSN: 0026-895X
    Electronic ISSN: 1521-0111
    Topics: Chemistry and Pharmacology , Medicine
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