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  • 1
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2021
    In:  Pakistan Journal of Medical and Health Sciences Vol. 15, No. 11 ( 2021-11-30), p. 3098-3100
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 15, No. 11 ( 2021-11-30), p. 3098-3100
    Abstract: Objective: The aim of this study is to compare in hospital morbidity and mortality in on pump versus off pump CABG. Methodology: All the patients undergoing CABG surgery were enrolled after taking informed consent. Demographic and postoperative variables were entered in the predesigned questionnaire and patients were followed for early outcomes after surgical procedure. Results: A total of 470 patients wasdivided in two groups 235 (on pump and off pump).The mean age of patients was 54.85 ± 9.57 (23-85).There were 400(85.1%) males and 70(14.9%) females. The total data of 470 patients was divided in two groups 235 in on Pump and 235 in off pump CABG.The mean age of patients was 54.85 ± 9.57 (23-85). There were 400(85.1%) males and 70(14.9%) females. Different clinical outcomes were compared in both groups (On-Pump versus Off-Pump CABG) by using Euro Score, we found Peripheral Disease in On-Pump CABG group compared with Off-Pump CABG as 11(4.68% vs 12(5.11%) with p-value=0.831 which was statistically insignificant, current data assessed lung disease in both groups as 11(4.68%) vs 13(5.53%) with statistically insignificant p-value (0.675). and unstable angina were 12(5.11%, p-value 1.00) patients founded and Peri and post myocardial infarction also assessed in both groups with p-value (0.74 & 1.20). respectively.Data regarding in hospital mortality was analyzed and found that 7(2.98%) in on pump group compare with off pump group was According to our research mean number of grafts placed in On-Pump CABG were 9(3.83%) with statistically insignificant p-value (0.611). Conclusion:Proof is presented that surgery on beating heart (Off-Pump) is as safe and effective as Conventional CABG, and cheaper than conventional surgery. However, it is uncertain whether the cost savings are sustained over a longer period of time. Keywords: Coronary artery Bypass grafting surgery, On Pump Off Pump
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2021
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  • 2
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2021
    In:  Pakistan Journal of Medical and Health Sciences Vol. 15, No. 9 ( 2021-09-30), p. 2422-2424
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 15, No. 9 ( 2021-09-30), p. 2422-2424
    Abstract: Background: Care of heart patients especially after coronary artery bypass graft (CABG) surgery can be difficult to manage especially in postoperative phase due to decreased cardiac output. Inotropes used to increase cardiac output during the peri or postoperative may cause harmful effects. Mechanical circulatory support devices, such as an intra-aortic balloon pump can be beneficial in such patients. Objective: To compare early outcomes of Intra-Aortic Balloon Pump (IABP) in Patients Undergoing Coronary Artery Bypass Grafting (CABG) Surgery Methods: Systematic random samples of 134 patients were registered from the department of cardiac surgery of Punjab Institute of Cardiology (PIC), Lahore undergone open heart surgery from December 2019 to May 2020. High-risk patients with hemodynamically stable undergoing scheduled CABG were included. The patients were divided into two groups. All information including gender and age were obtained using a structured questionnaire. Death and other complications were compared between two groups. Data was entered and analyzed using SPSS. Statistical test like chi- square and Independent t-tests were applied to obtain the required results and percentages. Results: Total 134 patients enrolled and equally divided into two groups. Group A (with IABP) have mean age was 47.58± 2.0 compared with Group B (without IABP) mean age 48.43± 4.31.There were 79(63.2%) males and 46(36.8%) were females enrolled. Hypertension, diabetes mellitus, smoking, Prior CVA, recent AMI and congestive heart failure remained statistically insignificant as p-value 〉 0.05. The duration of IABP, respiratory failure, renal dysfunction and length of ICU stay showed statistically significant p-value 〈 0.05. Reoperation for bleeding, acute AMI, pneumonia, stroke, wound infection and surgical mortality are statistically insignificant as pvalue 〉 0.05. Conclusion: In high-risk patients of coronary artery bypass graft, early implantation of an intra-aortic balloon pump improves the outcomes by reducing ICU stay and death; increased post-insertion creatinine levels have been proven to be an indication of approaching mortality. Keywords: Intra-aortic balloon pump, Coronary artery bypass graft, Creatinine levels, Low Cardiac Output Syndrome
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2021
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  • 3
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 4 ( 2022-04-26), p. 263-266
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 4 ( 2022-04-26), p. 263-266
    Abstract: Objective: Cardiopulmonary bypass in cardiac surgery is often associated with metabolic changes. So, we conducted this study in order to find the supremacy between two risk factors base excess and hyperlactatemia in early prediction of morbidity and mortality in ICU after cardiac surgery. Material and Methods: Intraoperative data of total of 100 patients who had cardiac surgery was recorded. Intraoperative and postoperative data of base excess and lactate levels were recorded at 1st, 6th, 12th and 24th hour in ICU. Two perioperative groups for B.E(Group 1 B.E 〈 +/-2.5 mmol: Group 2 B.E 〉 +/- 2.5 mmol) and lactate (Group 1 Lactate 〈 3 mmol: Group 2 Lactate 〉 mmol ) were created, Two post-operative groups for B.E(Group 1 B.E 〈 +/-5.0 mmol: Group 2 B.E 〉 +/- 5.0 mmol) and lactate( Group 1 Lactate 〈 5mmol: Group 2 Lactate 〉 5mmol )were created to find their correlation with early postoperative complications. Results: In our study ICU morbidity and mortality was more related to the lactate and base excess values in the early 24 hours. Progressive Hyperlactatemia and constant negative base excess values were both significantly associated with ICU complications. In the CPB period subgroup negative base excess was more superior in predicting ICU prognosis than Lactate. (P-value 0.001) similarly patients divided in subgroup BE 〉 +/- 5mmol/l had demonstrated superiority in making such prediction. Both CPB (0.013) and X.C (0.036) time were associated independently with ICU prognosis. .Longer ventilation times were also associated with bad ICU prognosis. Conclusion: Our study found negative base excess values in the early postoperative period to be superior in predicting ICU morbidity and mortality when studied at subgroup level both peri-operatively and postoperatively.
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 4 ( 2022-04-26), p. 270-272
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 4 ( 2022-04-26), p. 270-272
    Abstract: Objective: The aim of current study was to find out the factors causing Acute Kidney Injury (AKI) in the postoperative period of cardiac surgery. This prospective study, Peri-operative Anemia, Urine Output, gender, need for Intra-operative blood transfusion were analyzed for association of AKI. Material and Method: The study was conducted at Cardiac Center, QAMC Bahawalpur from January, 2019 to June, 2021. A total of 180 patients who underwent cardiopulmonary bypass for IHD and Valve surgery were studied. CPB hemoglobin levels, Blood Transfusion in OR, Gender specificity, Peri-operative urine output (Group1 UO 〈 4ml/kg/hr: Group 2 UO 〉 4ml/kg/hr) were correlated to establish their relationship in causing post-operative Acute Kidney Injury. The patients were divided into two groups one who had Acute Kidney Injury other who don’t. Results: Acute kidney injury developed in 20 out of 180 patients, current study showed insignificant relation between CPB time, X clamp time, Gender, Surgery type, MAP and Postoperative Acute Kidney Injury. Acute Kidney Injury was more associated with diabetes, need of blood transfusion, perioperative hemofiltration and reduced urine output. Conclusion: Current study showed that Acute Kidney injury is an avoidable complication if hemoglobin levels are kept above 8-9 gm/dl to ensure proper oxygen supply and need of Intraoperative hemofiltration and BT is reduced by reducing circuit length thus hemodilution and found a urine output less than 4 ml/kg/hr during cardiopulmonary bypass carries major risk for AKI. Keywords: AKI Acute Kidney injury CPB Cardiopulmonary bypass UO urine output MAP Mean Arterial Pressure
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
    Location Call Number Limitation Availability
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  • 5
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2021
    In:  Pakistan Journal of Medical and Health Sciences Vol. 15, No. 10 ( 2021-10-30), p. 2814-2816
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 15, No. 10 ( 2021-10-30), p. 2814-2816
    Abstract: Objective: The aim of this study is to compare early outcomes in on-pump and off-pump cardiac surgery. Methodology: All the patients undergoing CABG surgery were enrolled after taking informed consent. Demographic and postoperative variables were entered in the predesigned questionnaire and patients were followed for early outcomes after surgical procedure. Results: A total of 470 patients was divided in two groups 235 in ONCAB and 235 in OPCAB.The mean age of patients was 54.85 ± 9.57 with minimum and maximum age (23-85). There were 400(85.1%) males and 70(14.9%) females. The diabetic patients were 218(46.38%), hypertensive patients were 271(57.70%), patients having family history of cardiac diseases were 268(57.02%) smoker patients were 273(58.09%) and hyperlipidemia found in patients as 210(44.68%). There was a significant difference between Pneumonia (0.014) and Stroke (0.022) in ONCAB versus OPCAB groups, while the p-values of neurological dysfunction was insignificant. Conclusion: The results of current study showed that early complication in both procedures are nearly same. So we can say both techniques are equally safe and effective. Keywords: Coronary artery Bypass grafting surgery, ONCAB, OPCAB
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2021
    Location Call Number Limitation Availability
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