In:
Cardiology in the Young, Cambridge University Press (CUP), Vol. 30, No. 4 ( 2020-04), p. 482-488
Abstract:
Balloon pulmonary valvuloplasty is the treatment of choice for patients with moderate to severe pulmonary valve stenosis. Methods: An observational retrospective cross-sectional study including neonates, small infants, and children who underwent balloon pulmonary valvuloplasty in the period from 2007 to 2016 in the cardiac catheterisation unit of the paediatric cardiology department in Cairo University. Multivariable models were built to report the predictors of the outcome of balloon pulmonary valvuloplasty and its complications. Results: A total of 1200 patients were included in the study and divided according to age into 3 groups: neonates and early infants (n = 282), infants (n = 362), and children (n = 556). Procedural success, defined as a drop pressure gradient across the pulmonary valve to less than or equal to 50% of the baseline measurements, was achieved in 82.7% of the patients. Multivariate analysis revealed that only infundibular pulmonary stenosis (p value 0.032), supravalvular in association with valvular pulmonary stenosis (p value 〈 0.001), and pulmonary valve diameter by angiogram (p value 〈 0.001) were significant predictors of success. The presence of supravalvular in association with valvular pulmonary stenosis (p value 〈 0.001) was associated with a lower weight (p value 0.007) and higher right ventricular pressure before the intervention (p value 〈 0.001), and a minor immediate drop in the pressure gradient post-intervention (p value 〈 0.001) was found to be the most significant predictor of the occurrence of complications. Conclusion: The absence of infundibular and supravalvular stenosis and a large pulmonary valve diameter were the most significant predictors of success.
Type of Medium:
Online Resource
ISSN:
1047-9511
,
1467-1107
DOI:
10.1017/S1047951120000360
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
2020
detail.hit.zdb_id:
1078466-4
detail.hit.zdb_id:
2060876-7
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