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  • Online Resource  (2)
  • Wiley  (2)
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  • Online Resource  (2)
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  • Wiley  (2)
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  • 1
    In: Animal Science Journal, Wiley, Vol. 88, No. 2 ( 2017-02), p. 259-266
    Abstract: The objective of this study was to evaluate the effect of two different forage types on rumen fermentation parameters and profiles using a wireless data logger. Eight lactating cows were randomly assigned to one of two dietary treatments with a low forage diet with corn straw (CS) or a high forage diet with mixed forage (MF) as the forage source, respectively. Dietary physically effective neutral detergent fiber (peNDF) content was 11.3% greater in CS. Dry matter intake and milk fatty acid content decreased upon CS ( P   〈  0.05). Ruminal pH, temperature and oxidation reduction potential (ORP) were monitored for 14 weeks. The CS group had significantly higher pH but lower temperature and ORP compared to MF ( P   〈  0.01). With the CS diet regime, pH at the time before morning feeding, rumination and post‐ingestion were significantly higher than those in the MF group ( P   〈  0.05). However, times with the ruminal pH below 6.0 and 5.8 were significantly reduced ( P   〈  0.05), whereas ruminal pH below 5.6 tended to be lower ( P  = 0.07). The results indicated that rumen fermentation parameters were affected by forage types and dietary peNDF content might be predominant in ruminal pH regulation.
    Type of Medium: Online Resource
    ISSN: 1344-3941 , 1740-0929
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2095161-9
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  • 2
    In: Journal of Biophotonics, Wiley, Vol. 8, No. 9 ( 2015-09), p. 764-774
    Abstract: Despite initially positive responses, recurrences after Photodynamic treatment (PDT) can occur and there is need for improvement in the effectiveness of PDT. Our study uniquely showed that there was a significantly gap junctional intercellular communication (GJIC)‐dependent PDT cytotoxicity. The presence of GJIC composed of Connexin 32 increased the PDT phototoxicity in transfected HeLa cells and in the xenograft tumors, and the enhanced phototoxicity of Photofrin‐mediated PDT by GJIC was related with ROS and calcium pathways. Our study indicates the possibility that up‐regulation or maintenance of gap junction functionality may be used to increase the efficacy of PDT. The phototoxicity effect of Photofrin was substantially greater in Dox‐treated cells, which expressed the Cx32 and formed the GJ, than Dox‐untreated. magnified image The phototoxicity effect of Photofrin was substantially greater in Dox‐treated cells, which expressed the Cx32 and formed the GJ, than Dox‐untreated.
    Type of Medium: Online Resource
    ISSN: 1864-063X , 1864-0648
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2403788-6
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