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  • 1
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    Atividade farmacológica dos extratos da casca do caule do tropeiro. O Connarus fulvus, Planch
    FapUNIFESP (SciELO) ; 1988
    In:  Acta Amazonica Vol. 18, No. suppl 1-2 ( 1988), p. 231-240
    Details
    In: Acta Amazonica, FapUNIFESP (SciELO), Vol. 18, No. suppl 1-2 ( 1988), p. 231-240
    Abstract: Connarus fulvus Planch is populary utilized in the State of Goiás because it is said to be "good for the heart". This paper studied the pharmacological activities of the crude ethanolic extract (EE) of the powdered bark and of the hirosoluble fraction (HF) of the benzine/water partition. The EE and HF produced in rats andmices a decrease in locomotion, certain drowsiness, respiratory problems, insensitivity to pain and weakness of the posterior limbs. These effects were proportional to the administered doses. The DL50 in mice were 210+/-22 and 310+/-52mg/kg, i.p. for the EE and HF, respectively. The HF potenciated barbiturate - induced sleeping-time, reaction time to heat in the hot-plate and, in 80% of the cases, it antagonized the convulsive actions of PENTYLENETETRAZOL but not of STRYCHNINE. It protected the mice, in all of the cases, against the lethal action of PANCURONIUM and potenciated the action of SUCCINYLCHOLINE. in isolated tissues the HF potenciated, in 20% of the cases, contrations of the diaphragm in response to electrical stimulus of the phrenic nerve of the rats and reversed the neuromuscular blonde produced by d-TUBOCURARINE. In rat and guinea pig atriums electrically stimulated neither the chronotropism nor inotropism were altered. The injection of EE nor HF in rats under anesthetics produced hypotension (5 to mg/kg) while higher doses were lethal. The data obtained from studies didn't confirm direct action on the heart. The plant thus presented depressive action in the CNS, analgesic and anticonvulsive action while, it also annuled the effect of CURARE.
    Type of Medium: Online Resource
    ISSN: 0044-5967
    URL: Article
    DOI: 10.1590/1809-43921988185240
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 1988
    detail.hit.zdb_id: 2088290-7
    SSG: 12
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  • 2
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    Body composition among long distance runners
    FapUNIFESP (SciELO) ; 2020
    In:  Revista da Associação Médica Brasileira Vol. 66, No. 2 ( 2020-02), p. 180-186
    Details
    In: Revista da Associação Médica Brasileira, FapUNIFESP (SciELO), Vol. 66, No. 2 ( 2020-02), p. 180-186
    Abstract: RESUMO OBJETIVO O presente estudo objetivou examinar a composição corporal dos corredores de ultra-trail (UTR) e, adicionalmente, comparar dois grupos de acordo com o nível de participação (Regional vs. Nacional, respectivamente UTR-R e UTR-N). MÉTODOS A amostra foi composta por 44 corredores adultos masculinos (36,5±7,2 anos de idade; UTR-R: n=25; UTR-N: n=19). A composição corporal foi avaliada recorrendo à pletismografia de ar deslocado, bioimpedância elétrica e absorciometria de raios X de dupla energia. Adicionalmente, foi utilizado o Questionário de Frequência Alimentar. A comparação entre grupos foi realizada com base na prova t-student para amostras independentes. RESULTADOS Foram encontradas diferenças significativas por nível de competição para as seguintes variáveis dependentes: idade cronológica (em anos; UTR-R: 38,8±8,2 vs. UTR-N: 33,5±4,1); densidade corporal (em kg/L; UTR-R: 1,062±0,015 L/kg vs. UTR-N: 1,074±0,009); massa gorda (em kg; UTR-R: 12,7±6,8 kg vs. UTR-N: 7,6±2,7). CONCLUSÃO Os UTR-N tendem a ser mais jovens e apresentam valores superiores de densidade corporal e, consequentemente, valores menores de massa gorda, sendo a massa isenta de gordura semelhante entre os grupos. O presente estudo determinou o perfil dos corredores adultos masculinos de longa distância (ultra-trail), realçando a importância de uma cuidadosa regulação da massa corporal.
    Type of Medium: Online Resource
    ISSN: 1806-9282 , 0104-4230
    URL: Article
    DOI: 10.1590/1806-9282.66.2.180
    Language: English
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2020
    detail.hit.zdb_id: 2027973-5
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