In:
Yeni Üroloji Dergisi, Avrasya Uroonkoloji Dernegi, Vol. 16, No. 3 ( 2021-10-25), p. 254-261
Abstract:
Objective: In this study, we aimed to evaluate the relationship between biochemical recurrence time and the “cancer of the prostate risk assessment post-surgery” score (CAPRA-S) after radical prostatectomy (RP). Material and Methods: Retrospective evaluation was made of the records of 328 patients applied with RP for a diagnosis of clinically localized prostate cancer. The patients were separated into groups according to the CAPRA-S score determined according to the preoperative PSA level and pathological characteristics of the RP specimen and the biochemical recurrence time after RP. Results: The mean follow-up period was 76.9±34.5 months. Biochemical recurrence was determined in 23.2% (n:69) of the cases, as early recurrence in 71% (n:49) and late in 29% (n:20). According to the CAPRA-S score, 186 (62.4%) patients were classified as low risk, 66 (22.1%) as moderate risk, and 46 (15%) as high risk. The 3 and 5-year BRFS rates of all the patients were 88.9% and 81.8% respectively. Patients with a low CAPRA-S score were determined to have a statistically significantly higher 3 and 5-year BRFS rate than patients in the moderate and high groups. Early biochemical recurrence after RP was statistically significantly correlated only with lymph node involvement (OR: 2.42, 95% CI: 1.07-5.47, p=0.03). Conclusion: This study showed that the CAPRA-S score, which is effective in predicting the risk of biochemical recurrence after RP, was not effective in predicting the time of biochemical recurrence after RP. Keywords: Biochemical recurrence, CAPRA-S score, prostate cancer, radical prostatectomy
Type of Medium:
Online Resource
ISSN:
1305-2489
,
2687-1955
Uniform Title:
CAPRA-S ile radikal prostatektomi sonrası biyokimyasal rekürrens zamanı arasındaki ilişki
DOI:
10.33719/yud.2021;16-3
DOI:
10.33719/yud.2021;16-3-908452
Language:
Unknown
Publisher:
Avrasya Uroonkoloji Dernegi
Publication Date:
2021
detail.hit.zdb_id:
3023672-1
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