In:
Acta Endocrinologica, Oxford University Press (OUP), Vol. 121, No. 4 ( 1989-10), p. 533-537
Abstract:
Urinary excretion of growth hormone during night-time was measured by a highly sensitive enzyme immunoassay in 6 normal men for 18–24 days. Urinary GH excretion distributed widely from 0.12 to 4.7 pg/μmol creatinine and the coefficient of variation in each subject ranged from 37 to 57% (mean 49%). Urinary excretion of albumin and α 1 -microglobulin also showed moderate day-to-day variations (mean coefficients of variation: 37 and 42%, respectively). No correlation was found among urinary excretion of GH, albumin and α 1 -microglobulin. Plasma and urinary GH levels were determined every 5 min and 2 h, respectively, from 09.00 h to 17.00 h in 4 normal men. Urinary GH excretion every 2 h during daytime closely reflected the change of plasma GH levels in each subject, suggesting that physiological GH secretory dynamics are reflected on the urinary GH excretion. Repeated measurements of urinary GH excretion are required to evaluate GH secretory capacity.
Type of Medium:
Online Resource
ISSN:
0804-4643
,
1479-683X
DOI:
10.1530/acta.0.1210533
Language:
Unknown
Publisher:
Oxford University Press (OUP)
Publication Date:
1989
detail.hit.zdb_id:
1485160-X
Permalink