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  • 1
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    MIB 1 e p53 em lesões penianas escamosas intraepiteliais e invasoras; relações com o virus do papiloma humano (HPV)
    Revista Brasileira De Cancerologia (RBC) ; 2002
    In:  Revista Brasileira de Cancerologia Vol. 48, No. 1 ( 2002-03-29), p. 29-37
    Details
    In: Revista Brasileira de Cancerologia, Revista Brasileira De Cancerologia (RBC), Vol. 48, No. 1 ( 2002-03-29), p. 29-37
    Abstract: O objetivo deste estudo foi investigar o índice de proliferação celular (MIB-1) e a expressão de p53 em 24 carcinomas escamosos invasores (CEC), 7 lesões de alto grau (LIMAG) e 11 de baixo grau (LIMBG) do pênis, segundo a idade. Além do percentual, MIB1 e p53 foram avaliados por escores (baixos, de 1 a 5 e altos, de 6 a 9) segundo o grau de dispersão (1 a 3) de núcleos marcados versus intensidade da reação (1 a 3). A presença do HPV foi estimada pelos sinetes citohistopatológicos em todos os casos e, em 20 CEC, por hibridização in situ com sonda de amplo espectro. Resultados: a idade média (anos) foi de 62,3 nos CEC, de 41,6 nas LIMAG e 33,2 nas LIMBG. MIB1 foi expresso em 46,1% (LIMAG), 34,5% (CEC) e 13,3% (LIMBG). A p53 mostrou -se expressa nas LIMBG (90,9%), nos CEC (70,9% ) e nas LIMAG (57,1%). Todavia, os escores mais altos de MIB1 e de p53 (6 a 9) predominaram nos carcinomas e nas lesões de alto grau. Os sinetes associados ao HPV foram vistos em 100% das LIMAG, 87% dos CEC e 72,7% das LIMBG. O DNA do HPV foi detectado em 30% dos CEC (6/20). Conclusões: a p53 e o MIB1 mostraram-se avaliadores independentes, mais relacionados à gravidade da lesão; não houve relação significativa entre idade, p53 e MIB1. As lesões intraepiteliais ocorreram em faixas etárias semelhantes às descritas para a vulva e o colo uterino; todavia, o carcinoma peniano é mais tardio. Houve nítida associação com os sinetes de HPV porém a HIS mostrou baixa sensibilidade nos CEC (30%). O incremento dos escores de p53 com o grau da lesão sugere que de início há acúmulo por hiperfunção e inibição (pelas proteínas do HPV),as mutações ocorrendo durante a progressão. Já o MIB1 evidenciou que papilomas podem ter escores altos e CEC escores baixos (mormente os verrucosos, de comportamento mais loco-regional)
    Type of Medium: Online Resource
    ISSN: 2176-9745 , 0034-7116
    URL: Article
    DOI: 10.32635/2176-9745.RBC.2002v48n1.2260
    Language: Unknown
    Publisher: Revista Brasileira De Cancerologia (RBC)
    Publication Date: 2002
    detail.hit.zdb_id: 2058747-8
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  • 2
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    Uso de misoprostol retal para indução do parto em gestantes com amniorrexe prematura: ensaio clínico fase II
    FapUNIFESP (SciELO) ; 2003
    In:  Revista Brasileira de Ginecologia e Obstetrícia Vol. 25, No. 7 ( 2003-08), p. 491-499
    Details
    In: Revista Brasileira de Ginecologia e Obstetrícia, FapUNIFESP (SciELO), Vol. 25, No. 7 ( 2003-08), p. 491-499
    Type of Medium: Online Resource
    ISSN: 0100-7203
    URL: Article
    DOI: 10.1590/S0100-72032003000700005
    Language: English
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2003
    detail.hit.zdb_id: 2105176-8
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  • 3
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    Dinâmica espacial da clorose variegada dos citros em três regiões do Estado de São Paulo
    FapUNIFESP (SciELO) ; 2004
    In:  Fitopatologia Brasileira Vol. 29, No. 1 ( 2004-02), p. 56-65
    Details
    In: Fitopatologia Brasileira, FapUNIFESP (SciELO), Vol. 29, No. 1 ( 2004-02), p. 56-65
    Abstract: CVC is considered the most important disease of brazilian citrus industry but many aspects of its epidemiology are still unknown. This work aimed to characterize the spatial pattern of CVC affected trees in three regions (Northwest, Center and South) of São Paulo state, Brazil. Three orchards of Pêra sweet orange (Citrus sinensis) grafted on Rangpur lime (Citrus limonia) were evaluated twice a month by visual assessments from July 1998 to December 2000. For each evaluation all plants were inspected and assigned as diseased or healthy and cumulative maps were produced. The following analyses were performed: ordinary runs, isopath areas, Taylor law, dispersion index and foci structure and dynamics analysis. Ordinary runs indicated a trend to randomness. Isopath areas analysis showed few compact foci and a trend to uniform incidence in all areas. The other analysis showed few if any differences between regions and results that could classify CVC pattern as slightly aggregated.
    Type of Medium: Online Resource
    ISSN: 0100-4158
    URL: Article
    DOI: 10.1590/S0100-41582004000100009
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2004
    detail.hit.zdb_id: 2078802-2
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  • 4
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    Comportamento sazonal da clorose variegada dos citros em três regiões do Estado de São Paulo
    FapUNIFESP (SciELO) ; 2003
    In:  Fitopatologia Brasileira Vol. 28, No. 6 ( 2003-12), p. 633-641
    Details
    In: Fitopatologia Brasileira, FapUNIFESP (SciELO), Vol. 28, No. 6 ( 2003-12), p. 633-641
    Abstract: This work was to characterize the evolution of Citrus variegated chlorosis (CVC) related variables in plants of three regions in the State of São Paulo (Northeast, Center and South), in order to demonstrate differences in seasonal pattern of the pathogen, Xylella fastidiosa, vectors (sharpshooters), host [sweet orange (Citrus sinensis) 'Pera' grafted on Rangpur lime (Citrus limonia)] and disease. Twenty symptomatic plants were evaluated monthly from December 1998 to December 2000. The following variables were measured: number of new flushes (nf), percentage of symptomatic branches (psb), percentage of infected assymptomatic branches (piab), percentage of infected branches (pib), estimation of bacteria concentration (ebc), lower and higher temperatures, rain fall and number of sharpshooters in yellow traps. The correlations among variables were tested by Distributed Lag Analysis and the comparison between regions and season was performed by Kruskal-Wallis and Friedman ANOVA and Nemenyi test (p 〈 0,005). The CVC related variables (psb, piab, pib and ebc) showed seasonal patterns but no statistical differences were detected among seasons. The Northeast orchard showed the highest number of new flushes and percentage of symptomatic branches. The South orchard had the higher percentage of assymptomatic infected branches. There were no statistical differences among regions regarding the concentration of Xylella.
    Type of Medium: Online Resource
    ISSN: 0100-4158
    URL: Article
    DOI: 10.1590/S0100-41582003000600009
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2003
    detail.hit.zdb_id: 2078802-2
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  • 5
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    Paradigma da disseminação local do carcinoma epidermóide da base de língua
    FapUNIFESP (SciELO) ; 2004
    In:  Revista Brasileira de Otorrinolaringologia Vol. 70, No. 4 ( 2004-08), p. 471-477
    Details
    In: Revista Brasileira de Otorrinolaringologia, FapUNIFESP (SciELO), Vol. 70, No. 4 ( 2004-08), p. 471-477
    Abstract: AIM: To analyse the local spreading pattern through clinical delimitation of primary lesion extension as well as subsites involvement. STUDY DESIGN: Chart review. MATERIAL AND METHOD: Files of 290 patients with squamous cell carcinoma (SCC) of the base of the tongue from Department of Head Neck and Surgery and Otorhinolaryngology of Hospital Heliópolis, Hosphel, São Paulo, Brazil from 1977 to 2000, were analysed. They were staged through TNM from UICC, and then through thoygh K square text with Z x N (Cochran) tables for assessment of sites and size association of neoplasia in relation of medium line invasion. RESULTS: Male predominance (8:1) in 6th decade (41,0%), 83,8% were alcohol and tobacco dependent and 4,7% without this habbit. About symptoms, odinophagia (37,6%), lymphonode (21,7%) and medium time between tho first sympton and diagnosis of 6 months 62,0%). About staging, T1-T2 (18,3%), T3 (32,4%), T4(50,7%). Concerning local spreading: valecula (25,3%), epiglotis (18,7%), glottis (2,7%), anteriorly to lingual V (22,4%) and postero-lateraly to pharyngoepiglotic fold (6,6%), piriform sinus (2,2%). About medium line involvement (66,2%), 42,2% were (T2), 54,2% (T3) and 82,9% (T4). CONCLUSION: the SCC in T4 stage reach the medium line of base of the tongue in 82,9%.
    Type of Medium: Online Resource
    ISSN: 0034-7299
    URL: Article
    DOI: 10.1590/S0034-72992004000400006
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2004
    detail.hit.zdb_id: 2105179-3
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  • 6
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    Estudo clínico-epidemiológico do carcinoma epidermóide da base da língua
    FapUNIFESP (SciELO) ; 2003
    In:  Revista Brasileira de Otorrinolaringologia Vol. 69, No. 2 ( 2003-03), p. 175-179
    Details
    In: Revista Brasileira de Otorrinolaringologia, FapUNIFESP (SciELO), Vol. 69, No. 2 ( 2003-03), p. 175-179
    Abstract: INTRODUCTION: The asymptomatic evolution and early dissemination of squamous cell carcinoma (SCC) of the base of the tongue justify this report. AIM: clinical and epidemiological study of patients with SCC of the base of the tongue. STUDY DESIGN: Retrospective. MATERIAL AND METHOD: 290 patients with SCC of the base of the tongue (1977 to 2000), being 259 men (89,3%) and 31 women (10,7%) - relation 8:1; concerning race, 237 white (81,7%), 51 black (17,6%) and 2 yellow (0,7%) - relation 5:1. About age, the prevalence of 6th decade (41,0%) followed by 5th to 7th (22,7%), 8th (3,4%) and 9th (1,7%). These parameters were related to occupation, habits (tobacco and alcohol), TNM staging. For statistical analysis, were employed non-parametric tests: Wilcoxon, Kruskal Wallis, Kappa and McNemar. RESULTS: patients from industries (36,6%), trading, and high level education (34,5%), agriculture (7,9%) retired (7,3%) - with predominance of 30 to 59 years (61,1%) and time of complaint of 180 days (62,0%), the main symptom was odinophagia (37,2%), metastatic lymphonode (21,8%), disphagia (14,5%), tongue lesion (9,0%), hoarseness (6,9%), and others (10,2%). About habits, alcohol and tobacco (83,8%), tobacco alone (10,3%), alcohol (1,4%) and nobody (4,5%). Predominance of stages III and IV in relation to I and II - 9:1, being stages I, II and IV tobacco or alcohol addicts in 100%, followed by III, IVa, IVb and IVc (23,1%, 53, 8% and 23,1% respectively). About T, 241(83,1%) were T3 and T4, and 49 (16,9%) T1 and T2. For N, 61(21,6%) were N0, 39 N1(13,4%, 125 N2 (43,0%) and 65 N3 (22,4%), being level II(69,0%), followed by level III (13,5), I (11,6%) and IV (15,9%). CONCLUSIONS: The SCC of the base of the tongue is more usual in white men from 5th to 6th decade, having as risk factors alcohol and tobacco, tobacco among women, and the six initial months was prevalent concerning the complaint time is stages III and IV, being all cases I and II alcohol and tobacco users.
    Type of Medium: Online Resource
    ISSN: 0034-7299
    URL: Article
    DOI: 10.1590/S0034-72992003000200005
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2003
    detail.hit.zdb_id: 2105179-3
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  • 7
    Online Resource
    Online Resource
    Avaliação de métodos de determinação de água disponível em solo cultivado com algodão
    FapUNIFESP (SciELO) ; 2002
    In:  Pesquisa Agropecuária Brasileira Vol. 37, No. 3 ( 2002-03), p. 337-341
    Details
    In: Pesquisa Agropecuária Brasileira, FapUNIFESP (SciELO), Vol. 37, No. 3 ( 2002-03), p. 337-341
    Abstract: The main objective of this work was to evaluate two methods of determination of soil available water (a direct method and other in laboratory) and the effect of three levels of available water (10, 25 and 40%) in cotton crop (Gossypium hirsutum L. r. latifolium Hutch). This work was developed in green house condition in the Departamento de Solos e Engenharia Rural/Centro de Ciências Agrárias/Universidade Federal da Paraíba, located in Areia, PB, Brazil. A completely randomized block was utilized in a 2 x 3 factorial arrangement, with three replications. The variance analysis showed that the values of the available water in soil using the direct method were significantly (p 〈 = 0.05) bigger than the lab method. The management of irrigation in the cotton crop using 40% of available water determinated through the direct method showed the better results of evapotranspiration, leaf area, aboveground biomass. There was interaction of methods x levels of available water for all variables studied.
    Type of Medium: Online Resource
    ISSN: 0100-204X
    URL: Article
    DOI: 10.1590/S0100-204X2002000300015
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2002
    detail.hit.zdb_id: 2053197-7
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  • 8
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    Intervenção psicológica em cirurgia
    FapUNIFESP (SciELO) ; 2000
    In:  Psicologia em Estudo Vol. 5, No. 2 ( 2000), p. 23-31
    Details
    In: Psicologia em Estudo, FapUNIFESP (SciELO), Vol. 5, No. 2 ( 2000), p. 23-31
    Type of Medium: Online Resource
    ISSN: 1413-7372
    URL: Article
    DOI: 10.1590/S1413-73722000000200003
    Language: English
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2000
    detail.hit.zdb_id: 2145583-1
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  • 9
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    Avaliação de genótipos de caupi sob salinidade
    FapUNIFESP (SciELO) ; 2002
    In:  Revista Brasileira de Engenharia Agrícola e Ambiental Vol. 6, No. 3 ( 2002-12), p. 425-430
    Details
    In: Revista Brasileira de Engenharia Agrícola e Ambiental, FapUNIFESP (SciELO), Vol. 6, No. 3 ( 2002-12), p. 425-430
    Abstract: To assess the tolerance of 50 cowpea genotypes under salinity, experiments were conducted in greenhouse covered with fiberglass sheets. The salinity treatments applied in terms of electrical conductivity of saturation extract of soil (EC) were EC1 - 0.3; EC2 - 3.0; EC3 - 6.0; EC4 - 9.0 and EC5 - 12.0 dS m-1. The genotypes were classified for the salinity tolerance on the basis of the reduction in dry weight (%) of shoot. Under EC2, 36 genotypes were tolerant (T), 12 moderately tolerant (MT) and 2 moderately susceptible (MS); under EC3, 3 were T, 14 MT, 30 MS and 3 susceptible (S); under EC4, one was MS and 49 S and under EC5, all were S. The protein content of seed was influenced by salinity and varied with the genotype.
    Type of Medium: Online Resource
    ISSN: 1415-4366
    URL: Article
    DOI: 10.1590/S1415-43662002000300008
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2002
    detail.hit.zdb_id: 2164420-2
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  • 10
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    Fatores genéticos e de meio na produção de leite de caprinos leiteiros
    FapUNIFESP (SciELO) ; 2001
    In:  Revista Brasileira de Zootecnia Vol. 30, No. 3 ( 2001-06), p. 719-729
    Details
    In: Revista Brasileira de Zootecnia, FapUNIFESP (SciELO), Vol. 30, No. 3 ( 2001-06), p. 719-729
    Abstract: The objectives of this study were to evaluate the influence of environmental factors on milk production from dairy goats raised in the Brazilian Southeast and to estimate genetic parameters for this trait through least squares. The data originated from seven farms and three breeds (Alpine Brown, Saanen and Toggenburg). Milk yields obtained from 1,336 lactations were initially fitted to a diphasic function, whereby total milk production (TMP) was estimated. The overall mean and standard error for TMP were 635.31±39.75 kg. A significant year x kidding season interaction was observed. In all three kidding seasons a quadratic yearly trend of PLT was observed: it increased from 1986 until mid-1990, decreasing thereafter. Age of maximum PLT was estimated as 46.65 months. Alpine Brown was superior to Saanen in some farms, the opposite occurring in others, but both showed higher PLT values than Toggenburg. Estimated heritability and repeatability coefficients were 0.296±0.079 and 0.227±0.033, respectively. These results show low reliability due to the small number of observations or to inconsistent PLT estimates obtained through the biphasic function. Since PLT is a sex-limited trait, it is suggested the use of progeny tests as the most efficient selection method for bucks and artificial insemination for spreading the selected genetic material.
    Type of Medium: Online Resource
    ISSN: 1516-3598
    URL: Article
    DOI: 10.1590/S1516-35982001000300017
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2001
    detail.hit.zdb_id: 2078814-9
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