In:
European Journal of Organic Chemistry, Wiley, Vol. 2013, No. 14 ( 2013-05), p. 2864-2868
Abstract:
α‐Arylethanamines were investigated as organocatalysts for the α‐amination of branched aldehydes with azodicarboxylates. Optimization identified ( R )‐1‐(1‐naphthyl)ethanamine ( 1g ) as an effective and enantioselective organocatalyst; multifunctional chiral quaternary amino aldehydes were successfully obtained in excellent yields (up to 99 %) and with excellent enantioselectivities (up to 98 % ee ).
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2013.14
DOI:
10.1002/ejoc.201201701
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
1475010-7
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