In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 6 ( 2021-6-11), p. e0252503-
Abstract:
To clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan. Background Data regarding the association of detailed angiographic findings with in-hospital outcome after STEMI are limited in the p-PCI era. Methods Between January-2004 and December-2018, 1735 patients with STEMI (mean age, 68.5 years; female, 24.6%) who presented to the hospital in the 24-hours after symptom onset and underwent p-PCI were evaluated using the disease registries. The registry is an ongoing, retrospective, single-center hospital-based registry. Results The 30-day mortality rate and in-hospital mortality rate were 7.7% and 9.2%, respectively. Independent predictors of in-hospital mortality were ejection fraction (EF) 〈 40% [adjusted Odds Ratio (aOR), 4.446, p 〈 0.001], culprit lesions in the left coronary artery (LCA) (aOR, 2.940, p 〈 0.001) compared with those in the right coronary artery, Killip class 〉 II (aOR, 7.438; p 〈 0.001), chronic kidney disease (CKD) (aOR, 4.056; p 〈 0.001), final thrombolysis in myocardial infarction (TIMI) grades 0/1/2 (aOR, 1.809; p = 0.03), absence of robust collaterals (aOR, 17.309; p = 0.01) and hypertension (aOR, 0.449; p = 0.01). Conclusions Among the consecutive patients with STEMI, the in-hospital mortality rate after p-PCI significantly improved in the second half. Not only CKD, Killip class 〉 II, and EF 〈 40%, but also the angiographic findings such as culprit lesions in the LCA, absence of very robust collaterals, and final TIMI grades 〈 3 were associated with an increased risk of in-hospital mortality.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0252503
DOI:
10.1371/journal.pone.0252503.g001
DOI:
10.1371/journal.pone.0252503.g002
DOI:
10.1371/journal.pone.0252503.t001
DOI:
10.1371/journal.pone.0252503.t002
DOI:
10.1371/journal.pone.0252503.t003
DOI:
10.1371/journal.pone.0252503.t004
DOI:
10.1371/journal.pone.0252503.s001
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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