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  • Online Resource  (26)
  • MDPI AG  (26)
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  • Online Resource  (26)
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  • MDPI AG  (26)
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  • 1
    In: Metals, MDPI AG, Vol. 10, No. 2 ( 2020-02-17), p. 263-
    Abstract: Homogeneous heat treatment serves the significant roles in eliminating the segregation and tuning the microstructure of alloy ingot. It usually cost tremendous power and time to achieve a homogeneous microstructure for aluminum alloys. In this article, the hot extrusion was directly introduced on the spray deposited aluminum alloy 7055 ingot before performing heat treatment to explore the newly feasible homogeneous routine. Equiaxed grains without dendrites or PPB were obtained in our current parameters of spray deposition, which allowed the as-deposited alloy to be deformed without being subjected to pre-homogeneous heat treatment. Significant amount of stored energy was produced during hot extrusion at 420 °C with area reduction ratio of 6.25, which effectively promoted the homogeneity of microstructure and reduced significantly the heat treatment time. A newly feasible short routine, heat treatment at 450 °C /6 h + 470 °C/1 h following the hot extrusion, proved capable of obtaining a homogeneous microstructure for the spray deposited aluminum alloy 7055.
    Type of Medium: Online Resource
    ISSN: 2075-4701
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2662252-X
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  • 2
    Online Resource
    Online Resource
    MDPI AG ; 2020
    In:  Energies Vol. 13, No. 7 ( 2020-04-03), p. 1690-
    In: Energies, MDPI AG, Vol. 13, No. 7 ( 2020-04-03), p. 1690-
    Abstract: This study focuses on the nanostructure of shale samples with type III kerogen and its effect on methane adsorption capacity. The composition, pore size distribution, and methane adsorption capacities of 12 shale samples were analyzed by using the high-pressure mercury injection experiment, low-temperature N2/CO2 adsorption experiments, and the isothermal methane adsorption experiment. The results show that the total organic carbon (TOC) content of the 12 shale samples ranges from 0.70% to ~35.84%. In shales with type III kerogen, clay minerals and organic matter tend to be deposited simultaneously. When the TOC content is higher than 10%, the clay minerals in these shale samples contribute more than 70% of the total inorganic matter. The CO2 adsorption experimental results show that micropores in shales with type III kerogen are mainly formed in organic matter. However, mesopores and macropores are significantly affected by the contents of clay minerals and quartz. The methane isothermal capacity experimental results show that the Langmuir volume, indicating the maximum methane adsorption capacity, of all the shale samples is between 0.78 cm3/g and 9.26 cm3/g. Moreover, methane is mainly adsorbed in micropores and developed in organic matter, whereas the influence of mesopores and macropores on the methane adsorption capacity of shale with type III kerogen is small. At different stages, the influencing factors of methane adsorption capacity are different. When the TOC content is 〈 1.4% or 〉 4.5%, the methane adsorption capacity is positively correlated with the TOC content. When the TOC content is in the range of 1.4–4.5%, clay minerals have obviously positive effects on the methane adsorption capacity.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2437446-5
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  • 3
    In: Nanomaterials, MDPI AG, Vol. 11, No. 7 ( 2021-07-14), p. 1827-
    Abstract: The cost-effective conversion of low-grade heat into electricity using thermoelectric devices requires developing alternative materials and material processing technologies able to reduce the currently high device manufacturing costs. In this direction, thermoelectric materials that do not rely on rare or toxic elements such as tellurium or lead need to be produced using high-throughput technologies not involving high temperatures and long processes. Bi2Se3 is an obvious possible Te-free alternative to Bi2Te3 for ambient temperature thermoelectric applications, but its performance is still low for practical applications, and additional efforts toward finding proper dopants are required. Here, we report a scalable method to produce Bi2Se3 nanosheets at low synthesis temperatures. We studied the influence of different dopants on the thermoelectric properties of this material. Among the elements tested, we demonstrated that Sn doping resulted in the best performance. Sn incorporation resulted in a significant improvement to the Bi2Se3 Seebeck coefficient and a reduction in the thermal conductivity in the direction of the hot-press axis, resulting in an overall 60% improvement in the thermoelectric figure of merit of Bi2Se3.
    Type of Medium: Online Resource
    ISSN: 2079-4991
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2662255-5
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  • 4
    In: Foods, MDPI AG, Vol. 11, No. 19 ( 2022-09-30), p. 3042-
    Abstract: Chronic kidney disease caused by a high-fat diet (HFD)-induced metabolic syndrome has received widespread attention. Lycopene has a wide range of biological activities and can improve a variety of chronic diseases through anti-inflammatory effects. In this study, HFD-fed mice were used as a metabolic syndrome model to evaluate the protective effect of lycopene in a sustained-release vehicle (bilosomes) in the small intestine against renal injury and to determine whether the TLR4/MyD88 pathway and related metabolic pathways are involved in this process. The results showed that lycopene bilosomes alleviated HFD-induced kidney damage, as evidenced by lower serum urea nitrogen, creatinine, and uric acid levels. Histopathology studies showed that lycopene bilosomes attenuated HFD-induced tubular cell and glomerular injury. In addition, Elisa, RT-PCR, and Western blotting results showed that lycopene bilosomes also reduced the expression of inflammatory factors such as TLR4, MyD88, NF-kB, TNF-a, and IL-6 in mouse kidneys. The mechanism was to attenuate renal inflammatory response by inhibiting the TLR4/MyD88 inflammatory pathway. These findings suggested that lycopene can alleviate nephritis and metabolic disorders caused by HFD, inhibiting the TLR4/MyD88 inflammatory pathway and its downstream pro-inflammatory cytokines and further regulating the vitamin K metabolism, beta-alanine metabolism, and glutathione metabolism pathways to relieve chronic nephritis.
    Type of Medium: Online Resource
    ISSN: 2304-8158
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2704223-6
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  • 5
    Online Resource
    Online Resource
    MDPI AG ; 2018
    In:  ISPRS International Journal of Geo-Information Vol. 7, No. 1 ( 2018-01-21), p. 32-
    In: ISPRS International Journal of Geo-Information, MDPI AG, Vol. 7, No. 1 ( 2018-01-21), p. 32-
    Type of Medium: Online Resource
    ISSN: 2220-9964
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2655790-3
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  • 6
    Online Resource
    Online Resource
    MDPI AG ; 2020
    In:  International Journal of Environmental Research and Public Health Vol. 17, No. 8 ( 2020-04-21), p. 2846-
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 8 ( 2020-04-21), p. 2846-
    Abstract: The purpose of this study was to investigate the effects of surface slope and body posture (i.e., seated and standing) on lower extremity joint kinetics during cycling. Fourteen participants cycled at 250 watts power in three cycling conditions: level seated, uphill seated and uphill standing at a 14% slope. A motion analysis system and custom instrumented pedal were used to collect the data of fifteen consecutive cycles of kinematics and pedal reaction force. One crank cycle was equally divided into four phases (90° for each phase). A two-factor repeated measures MANOVA was used to examine the effects of the slope and posture on the selected variables. Results showed that both slope and posture influenced joint moments and mechanical work in the hip, knee and ankle joints (p 〈 0.05). Specifically, the relative contribution of the knee joint to the total mechanical work increased when the body posture changed from a seated position to a standing position. In conclusion, both surface slope and body posture significantly influenced the lower extremity joint kinetics during cycling. Besides the hip joint, the knee joint also played the role as the power source during uphill standing cycling in the early downstroke phase. Therefore, adopting a standing posture for more power output during uphill cycling is recommended, but not for long periods, in view of the risk of knee injury.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2175195-X
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  • 7
    In: Materials, MDPI AG, Vol. 14, No. 16 ( 2021-08-19), p. 4674-
    Abstract: Cell-penetrating peptides (CPPs), as non-viral gene delivery vectors, are considered with lower immunogenic response, and safer and higher gene capacity than viral systems. In our previous study, a CPP peptide called RALA (arginine rich) presented desirable transfection efficacy and owns a potential clinic use. It is believed that histidine could enhance the endosome escaping ability of CPPs, yet RALA peptide contains only one histidine in each chain. In order to develop novel superior CPPs, by using RALA as a model, we designed a series of peptides named HALA (increased histidine ratio). Both plasmid DNA (pDNA) and siRNA transfection results on three cell lines revealed that the transfection efficacy is better when histidine replacements were on the C-terminal instead of on the N-terminal, and two histidine replacements are superior to three. By investigating the mechanism of endocytosis of the pDNA nanocomplexes, we discovered that there were multiple pathways that led to the process and caveolae played the main role. During the screening, we discovered a novel peptide-HALA2 of high cellular transfection efficacy, which may act as an exciting gene delivery vector for gene therapy. Our findings also bring new insights on the development of novel robust CPPs.
    Type of Medium: Online Resource
    ISSN: 1996-1944
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2487261-1
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  • 8
    In: Materials, MDPI AG, Vol. 16, No. 14 ( 2023-07-10), p. 4918-
    Abstract: Maraging steel is a prominent category of ultrahigh-strength steel (UHSS) characterized by excellent comprehensive properties, and it finds wide applications in manufacturing load-bearing structural components. In this study, a novel tungsten-containing maraging steel, C-250W, was designed. The effects of aging treatments on the mechanical properties, microstructure, precipitations, and reverted austenite of C-250W steel were investigated. The results revealed that the optimal combination of strength and toughness could be achieved through an aging treatment of C-250W steel carried out for 5 h at 480 °C after solution treatment at 1000 °C for 1 h. As the aging temperature increased, the proportion of dimples in the impact fracture gradually decreased while that of quasi-cleavage increased, leading to a reduction in Charpy impact energy. The boundary of martensitic lath decomposed gradually as the aging temperature increased, and it disappeared entirely at temperatures higher than 550 °C. Moreover, the aging process resulted in the formation of phases, including spherical Fe2M (M represents Mo, W) and thin strip-shaped Ni3N (N represents Mo, Ti) precipitates. These precipitates coarsened from 5 nm to 50–200 nm with increasing aging temperature. Additionally, the content of reverted austenite increased with the aging temperature. Within the temperature range of 400 °C to 500 °C for aging treatment, the content of film-shaped reverted austenite was approximately 3%, primarily distributed at the boundary of martensite lath. When the aging temperature exceeded 550 °C, the content of reverted austenite reached 20.2%, and its morphology changed from film-shaped to block-shaped, resulting in a decline in strength and toughness.
    Type of Medium: Online Resource
    ISSN: 1996-1944
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2487261-1
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  • 9
    Online Resource
    Online Resource
    MDPI AG ; 2019
    In:  Materials Vol. 12, No. 18 ( 2019-09-09), p. 2905-
    In: Materials, MDPI AG, Vol. 12, No. 18 ( 2019-09-09), p. 2905-
    Abstract: Cylindrical bodies in uniform flows can be coated with a porous medium as a passive flow and noise control method in an effort to reduce the acoustic effects of vortex shedding. To date, the employed open-cell porous materials typically possess a randomized internal structure. This paper presents the design and validation of a novel 3-D printed structured porous coated cylinder that has significant flexibility, in that the porosity and pores per inch of the porous coating can be modified independently and relatively easily. The performance of the structured porous coating design is compared against porous polyurethane and metal foam with the same coating dimensions and similar pores per inch and porosity via an experimental acoustic investigation, revealing strong similarity in the passive noise control performance of each material type. A numerical comparison illustrates the similarities of the wake structure of the 3-D printed porous coated cylinder to an equivalent Darcy–Forchheimer model simulation that represents a randomized internal porous structure. The performance similarities of these different porous material types indicate that a structured porous geometry can be used to understand the internal flow behavior of the porous medium responsible for reducing the cylinder vortex shedding tone that is otherwise extremely difficult or impossible with typical randomized porous structures. Moreover, significant potential exists for the porous structure to be further optimized or smartly tailored by architectural design for different control purposes, coating geometries and dimensions, and working conditions.
    Type of Medium: Online Resource
    ISSN: 1996-1944
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2487261-1
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  • 10
    In: Symmetry, MDPI AG, Vol. 12, No. 6 ( 2020-06-10), p. 991-
    Abstract: We evaluated the symmetry of theoretical and experimental analysis of water contamination such as non-aqueous phase liquid (NAPL) by using amplitude variations with offset analysis (AVO) of ground-penetrating radar (GPR) data. We used both theoretical and experimental approaches for AVO responses of GPR to small distributions of contamination. Theoretical modeling is a tool used to confirm the feasibility of geophysical surveys. Theoretical modeling of NAPL-contaminated sites containing wet sand—both with the water and light non-aqueous phase liquid—was applied by keeping in consideration the GPR AVO analysis in acquisition. Reflectivity was significantly altered with the changes in the contents of water and NAPL during modeling. The wet and dry sands introduced in our model changed two major phenomena: one, the wave pattern—implying a slight phase shift in the wave; and two, an amplitude jump with the dim reflection radar gram observed in the model. Experimental data were collected and analyzed; two observations were recorded during physical data analysis. First, relative permittivity confirmed the presence of NAPL in an experimental tank. Second, reflection patterns with jumps in amplitude and changes in polarity confirmed the theoretical investigation. Our results demonstrate that GPR AVO analysis can be as effective for detection of non-aqueous phase liquid (NAPLs) as it has been used to determine moisture contents in the past. The theoretical and experimental models were in symmetry, and both found a jump in reflection strength. The reflection pattern normally jumped with NAPL-intrusion. From the perspective of water contamination, this study emphasizes the need to take into account the impact of GPR AVO analyses along with the expert’s adaptive capacities.
    Type of Medium: Online Resource
    ISSN: 2073-8994
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2518382-5
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