In:
The Journal of Immunology, The American Association of Immunologists, Vol. 196, No. 1_Supplement ( 2016-05-01), p. 130.5-130.5
Abstract:
In 2012, Mohamed et al.(J Med Econ) estimated preference weights for changes in the administration features of immunoglobulin (IG) therapies among patients with self-reported primary immunodeficiency disorder (PIDD). The preference weights were estimated using a discrete-choice experiment survey that asked respondents to choose between hypothetical treatments with varying administration features. However, the authors did not discuss the implications of their results on patients’ preferences for currently available IG therapies with specific combinations of the elicited features. Transferring preference results from Mohamed et al. allowed us to evaluate current treatment options not considered during the original study. This transfer of preference information is commonplace in economics, but not in health applications where it is done almost exclusively with treatment outcomes and not treatment administration features. The aim of this study was to assess patients’ relative preferences for currently available IG treatments in terms of their administration features as elicited by Mohamed et al. To achieve this objective, we approximated a preference-weight function through visual examination of the weights plotted in the publication. This function provides a calculation of preference scores for any IG treatment described with the attributes studied in Mohamed et al. This research suggests a general tendency in PIDD patients to prefer the administration features associated with intravenous therapies over subcutaneous therapies. The evaluation of IG therapies with the approximated preference function highlights how attribute preferences can be considered jointly in clinically meaningful treatment profiles.
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.196.Supp.130.5
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
2016
detail.hit.zdb_id:
1475085-5
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