In:
Diabetes/Metabolism Research and Reviews, Wiley, Vol. 30, No. 6 ( 2014-09), p. 489-496
Abstract:
Little is known about the optimal cut‐off point of fasting plasma glucose for the diagnosis of gestational diabetes mellitus for pregnant Chinese women. This study investigates the relationship between gestational fasting plasma glucose and several variables: neonatal birth weight, prenatal blood pressure and dystocia rate of pregnant women. In this study, we hoped to provide a useful tool to screen gestational diabetes mellitus in pregnant Chinese women. Methods For 1058 pregnant women enrolled in our hospital at pregnancy weeks 22–30, fasting plasma glucose, neonatal birth weight and prenatal blood pressure, as well as dystocia conditions, were examined. We analysed the correlations between the following: gestational fasting plasma glucose and neonatal birth weight; prenatal blood pressure and gestational fasting plasma glucose as well as dystocia rate and gestational fasting plasma glucose group. Results A modest correlation was observed between gestational fasting plasma glucose and neonatal birth weight ( r = 0.093, p = 0.003). The macrosomia rate was smallest when the gestational fasting plasma glucose was in the range 3.51–5.5 mmol/L. Prenatal blood pressure increased linearly with increasing gestational fasting plasma glucose ( p = 0.000). There was a significant difference between the dystocia rates in different fasting plasma glucose groups (chi‐squared = 13.015, p = 0.043). The results showed that the dystocia rate significantly increased when gestational fasting plasma glucose was 〉 4.9 mmol/L; p = 0.03, OR = 2.156 (95% CI, 1.077–4.318). Conclusion We suggest that the optimal range of gestational fasting plasma glucose for pregnant Chinese women is in the range 3.5–4.9 mmol/L. Copyright © 2014 John Wiley & Sons, Ltd.
Type of Medium:
Online Resource
ISSN:
1520-7552
,
1520-7560
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2001565-3
Permalink
