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Properties and feasibility of using cancer stem cells in clinical cancer treatment (2016)

Xiao-Mei Gao, Rui Zhang, Qiong-Zhu Dong, Lun-Xiu Qin

Chinese Anti-cancer Association (CACA)

In: Cancer Biology & Medicine

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Publikationsdatum: 2016-12-31

Beschreibung: Cancer treatment failure, drug resistance, or metastatic recurrence are thought to be caused mainly by the existence of a very smallnumber of cancer stem cells (CSCs). The characteristics of this subgroup of cells include self-renewal, tumorigenesis, multipledifferentiation and high invasiveness, metastasis, and drug resistance potential. Many studies have demonstrated that CSCs playimportant roles in tumor growth, spread and metastatic relapse after treatment, and are closely related to the prognosis of patients.From a therapeutic viewpoint, deep insights into the CSCs biology, development of specific therapeutic strategies for targetingCSCs, and characterization of their microenvironment could be an ideal way to combat cancer.

Digitale ISSN: 2095-3941

Thema: Medizin

Publiziert von Chinese Anti-cancer Association (CACA)

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