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  • 1
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 159, No. 46 ( 2018-11), p. 1876-1881
    Abstract: Abstract: The mechanical circulatory support (MCS) program of the Semmelweis University Heart and Vascular Centre has become established over the last five years. The main requirements of our MCS program to be developed first were the Heart Transplantation and Heart Failure Intensive Care Unit and a well trained medical team. The wide range of mechanical circulatory support devices provides suitable background for the adequate treatment of our patients in all indications. In this review, we present our results related to extracorporeal membrane oxygenation (ECMO) supports performed in the last five years. Between 2012 and 2017, we applied MCS support in 140 cases, among them 111 patients received ECMO support. The leading indications of ECMO support were the following: primary graft failure after heart transplantation (33 cases), postcardiotomy cardiogenic shock (18 patients), acute decompensation of end-stage heart failure (14 patients), acute myocardial infarction complicated with refractory cardiogenic shock (37 patients), cardiogenic shock developed after transcatheter aortic valve implantation (3 patients), malignant arrhythmia due to drug intoxication (1 patient) and acute respiratory distress syndrome (4 cases). The mortality of patients receiving ECMO support was 46%. The analysis of the results of ECMO support needs to change our approach. The mortality results show that we lost the half of our patients. However, the mortality in the conventionally treated patients would have been 100% without ECMO. In fact, we could save the life of half of these patients. Orv Hetil. 2018; 159(46): 1876–1881.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2018
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  • 2
    Online Resource
    Online Resource
    Akademiai Kiado Zrt. ; 2018
    In:  Orvosi Hetilap Vol. 159, No. 47 ( 2018-11), p. 1981-1987
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 159, No. 47 ( 2018-11), p. 1981-1987
    Abstract: Abstract: Introduction: The usefulness of nasal packing after endoscopic sinus surgery is still debated in the literature. Aim: Our aim was to evaluate the effects of a new chitosan-based nasal dressing in animal model. Methods: Standard mucosal damage was caused in both nostrils during endoscope-assisted procedure in ten rabbits. Chitosan nasal packing was inserted in a randomly selected nasal fossa of each animal, while the other side was left unpacked. Symptoms were evaluated during nasal endoscopy on the 12th postoperative week. The degree of mucosal oedema, crusting, adhesions and the nasal discharge were observed according to the modification of the grading system of Berlucchi et al. The higher scores indicated the worse complaints. Results: Assessing the adhesion formation, 1 point was given (mean: 0.1; standard deviation [SD]: 0.32) for the unpacked side, while in the tamponated side no adhesion formation was observed. The total score of crusting in the non-packed side was lower with 1 point (total score: 9, mean: 0.90; SD: 0.74) than in the chitosan side (total score: 10, mean 1.00; SD: 0.82). Discharge or mucosal oedema were not observed during the follow-up period. The mean rate, measured with electronmicroscopy, was 22.06% (SD: 0.25) in the chitosan side, while in the non-packed side it was 36.11% (SD: 0.48). The differences did not show any significance (p = 0.806). Conclusion: During the examinations, none of the animals suffered complications. The symptoms of the packed and the non-packed nasal cavities did not differ significantly on the basis of our examinations. Orv Hetil. 2018; 159(47): 1981–1987.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2018
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  • 3
    Online Resource
    Online Resource
    Akademiai Kiado Zrt. ; 2014
    In:  Orvosi Hetilap Vol. 155, No. 31 ( 2014-08), p. 1228-1235
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 155, No. 31 ( 2014-08), p. 1228-1235
    Abstract: Introduction: Reporting liability of family physicians/general practitioners is the keystone for proper surveillance of infectious diseases. Aim: The aim of the study was to find out why some of the family physicians neglect to report infectious diseases to the health authorities and determine their motivation and attitude towards the infectious disease reporting system. Method: Self-fill-in questionnaire was used to obtain data. Of the 228 family physicians who were called to participate in the study 116 family physicians sent back evaluable questionnaires. Descriptive statistic method was used to analyze the data and determine the reporting frequencies and ratios. Results: Family physicians reported nearly 50% of all reported cases of infectious diseases. The main reason of underreporting was the lack of knowledge about the rules of the reporting system. According to most family physicians, an online based reporting system would be much more efficient instead of a paper based one. Conclusions: The authors conclude that education of family physicians would be mandatory in order to improve reporting of infectious diseases. Orv. Hetil., 2014, 155(31), 1228–1235.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2014
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  • 4
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 160, No. Supplement 2 ( 2019-09), p. 2-20
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2019
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  • 5
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 152, No. 1 ( 2011-01), p. 3-13
    Abstract: Chest wall desmoids are rare, borderline tumors. Radical surgical excision is considered to be the primary treatment. Tendency of desmoids to infiltrate the chest wall, the shoulder girdle, lung parenchyma, brachial plexus and vital components of the mediastinum provides a difficult surgical challenge in the efforts of achieving microscopically negative margins. Implantation of synthetic meshes and reconstructive plastic surgical techniques might be necessary to perform in order to preserve stability of the thorax, and to achieve optimal functional and aesthetic results. Multidisciplinary surgeries may result in a high rate of morbidity even in specialized centers. Within the framework of a retrospective multicenter review, authors assessed surgical techniques implemented in the case of patients who underwent surgical management for sporadically appearing chest-wall and intra-thoracic desmoids, and reviewed the relevant literature. Orv. Hetil., 2011, 152, 3–13.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2011
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  • 6
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 160, No. 40 ( 2019-10), p. 1584-1590
    Abstract: Abstract: Introduction: Malignant tumours of the sinonasal region – including those with invasion of the skull base – necessitate surgical resection. The majority of the cases give an opportunity to perform the procedure via minimally invasive, endoscopic approach, without external, craniofacial surgery. Aim: To assess our clinical experience in treating anterior skull base malignancies, performing minimally invasive endoscopic transcribriform resection. Method: Between February 2015 and July 2017, four male and one female patient underwent minimally invasive, endoscopic skull base procedure. The mean age was 64.6 years (59–70, median: 66). Every surgery was performed via transnasal, endoscopic transcribriform approach. In two cases Kadish C esthesioneuroblastomas, while in one case a T3N0 sinonasal non-differentiated carcinoma, a T1N0 intestinal type adenocarcinoma and a T4N0 squamous cell carcinoma was the indication of surgery, respectively. Results: The mean follow-up time was 22.8 months, between 14 and 46 months. Intraoperative complications did not occur during the procedures. Regarding the postoperative period, liquorrhoea and pneumocephalus occurred in one case. Complications were solved with lumbar drainage. During follow-up, neither residual nor recurrent tumour was observed in our patients. Conclusion: Endoscopic transcribriform resection of the skull base malignancies is a safe and viable alternative to the traditional open approach. Orv Hetil. 2019; 160(40): 1584–1590.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2019
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  • 7
    Online Resource
    Online Resource
    University of Szeged ; 2009
    In:  Jelenkori Társadalmi és Gazdasági Folyamatok Vol. 4, No. 3-4 ( 2009-01-01), p. 16-20
    In: Jelenkori Társadalmi és Gazdasági Folyamatok, University of Szeged, Vol. 4, No. 3-4 ( 2009-01-01), p. 16-20
    Abstract: Pig- or pork meat is still keeping its leading role in meat production- and consumption -ahead of poultry - its main rival - which has made a huge development during the past decades. The pig sector has to face huge difficulties almost continuously, anyway periodi-cally - in the EU and in Hungary, as well. The EU has included pork in a category called „light market regulation product paths", hence the development of production/consumption is exposed mostly to the extremities of markets. Because of this, a strong fluctuation in buy-up prices has also been observable up to now, according to the well-known cyclicism in the pig sector, as well as a consequence of the various pig illnesses, changes in con-sumer habits, and so on. Due to the lack of market regulations, an absurd fenomena oc-cures very often, notably: parallel to the decreasing slaughter hog procurement prices -that of forage increase. Consequently, farms have to try to minimise (or being more pre-cise) to optimise costs for the sake of their sustainability, and keeping up competitiveness. Concerning the cost-structure of animal farming, no doubt that costs of forages are deter-minant, especially in case of pig farming it can reach as much as 60-70 percent of the total. Consequently, beside applying „novel" forages, increasing effectiveness of the so-called „traditional ones" is also badly needed.
    Type of Medium: Online Resource
    ISSN: 2676-9867 , 1788-7593
    Language: Hungarian
    Publisher: University of Szeged
    Publication Date: 2009
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  • 8
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 160, No. 1 ( 2019-01), p. 2-11
    Abstract: Abstract: Since 2017, the nomenclature of Fusarium, Acremonium and Sarocladium species have changed, as these morphologically homogeneous, but phylogenetically heterogeneous species and species complexes may be differentiated using MALDI–TOF MS examination, analyzing nucleotic sequences. This resulted in taxonomical changes. We summarize the clinical course, diagnostic and therapeutic options of keratitis caused by Fusarium and Sarocladium. The challenge of Fusarium and Sarocladium keratitis management for an ophthalmologist lies in delayed diagnosis and therapy, fulminant progression and penetration of the Descemet’s membrane, restricted availability, poor penetration of antifungal agents and therapy resistance. The diagnosis is based on the clinical history of corneal trauma or contact lens wear, PCR and MALDI–TOF MS, confocal microscopic examination, microbiological culture and light-microscopic analysis of corneal scrapings. As primary conservative treatment, 5% natamycin eye drops have to be used and with results of an antimycogram, topical 1% voriconazole or 0.15–0.25% amphotericin B, in some cases 0.02% polyhexamethylene-biguanide (PHMB) may be applied. Fusarium keratitis may benefit from additional 2 × 200 mg oral voriconazole treatment, daily. In therapy resistant cases, early, large diameter penetrating keratoplasty (PKP) has to be performed, with complete removal of the infected area. With late diagnosis, delayed specific treatment and surgery, mycotic hyphae may penetrate the Descemet’s membrane, leading to the loss of vision and enucleation in about every fourth patient. In our paper, we also present the heterogeneous clinical history of five Fusarium and Sarocladium keratitis cases. Orv Hetil. 2019; 160(1): 2–11.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2019
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  • 9
    Online Resource
    Online Resource
    University of Szeged ; 2010
    In:  Jelenkori Társadalmi és Gazdasági Folyamatok Vol. 5, No. 1-2 ( 2010-01-01), p. 219-225
    In: Jelenkori Társadalmi és Gazdasági Folyamatok, University of Szeged, Vol. 5, No. 1-2 ( 2010-01-01), p. 219-225
    Abstract: In 1988-1989 a stream of East Germans sought refugee in Hungary at the Embassy of West Germany in Budapest. The three countries taking part in the issue made different solutions to deal with the increasing problem. The East German leadership tried to call back the refugees and calm down the emigration process, but it had lost its confidence. West Germany tried to solve the problem not only on the level of consulship but exten-sively, in part with recognizing the status those waiting for West German citizenship and those for refugee status - without any success. In the interest of the resolution and bring the Hungarian leadership to their point of view, they tried to make use of the international organizations. However, the Hungarian leadership made efforts to stay out of the issue to get the two German states make an agreement. But there was no chance for that so Buda-pest gave up its quasi neutrality and tried to solve the problem opening the border by avoiding Hungary to turn into a refugee camp of the region. Besides making this ad hoc arrangement, the whole issue needed more radical crisis management, not only in Hungary.
    Type of Medium: Online Resource
    ISSN: 2676-9867 , 1788-7593
    Language: Hungarian
    Publisher: University of Szeged
    Publication Date: 2010
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  • 10
    In: Orvosi Hetilap, Akademiai Kiado Zrt., Vol. 159, No. 39 ( 2018-09), p. 1593-1601
    Abstract: Abstract: Introduction and aim: The aim of our study was to investigate changes in clinical staging N (lymph node) and M (distant metastasis) in patients who receive PET/CT-based 3D radiotherapy within complex oncological treatment, and compare to conventional cross-sectional imaging staging technique. We also investigated the presence of PET/CT-detected second tumors and the effect of PET/CT on therapeutic decisions. Method: From the 1st of January 2015 to the 30th of November 2016, 192 patients (n = 192) were treated with PET/CT-based radiation (109 head, 44 lung, 28 rectum and 11 cervical localization) in the Oncoradiology Institute of the Health Center of the University of Kaposvár. All patients received conventional cross-sectional and PET/CT imaging in accordance with the valid investigation protocol. The average time interval between the two cross-sectional investigations was 5.2 weeks. Clinical N and M staging was performed on the basis of the classification of the American Joint Committee on Cancer (AJCC) and the Union of International Cancer Control (UICC). Results: By analyzing the clinical stages N and M separately, based on the results of the PET/CT studies, the N stage was changed in 77 cases and the M stage changed in 31 cases. Overall, the PET/CT study resulted in higher clinical stages in 68 (35.4%) patients and lower clinical stages in 14 (7.3%) patients. The treatment plan was changed in 9% of the patients (n = 18) (definitive versus palliative treatment) and the extension of radiotherapy treatment target volume (PTV) was indicated in 20% of the patients (n = 39) due to the change in clinical lymph node status. PET/CT also detected secondary tumors in 15 (8%) patients. Conclusion: Based on our results, the addition of PET/CT to conventional cross-sectional staging imaging permits a more accurate clinical classification of N and M stages and significantly influences therapeutic decisions. PET/CT imaging also provides a great help in detecting occult second tumors. The results of our Institute harmonize with the international data available in the literature. Orv Hetil. 2018; 159(39): 1593–1601.
    Type of Medium: Online Resource
    ISSN: 0030-6002 , 1788-6120
    Language: Hungarian
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2018
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