In:
Bulletin de l'Académie Vétérinaire de France, PERSEE Program, Vol. 146, No. 3 ( 1993), p. 315-326
Abstract:
Biological properties of feline immunodeficiency (F.I.V.). replication and persistence. The biological and serological properties of feline immunodeficiency virus (FIV) isolates obtained from six cats that have been infected at the same time and age with FIV-Petaluma were examined in the course of time. In general, the time required for first detection of viral replication in peripheral blood mononuclear cells (PBMC) did not significantly differ among isolates ( 〉 12 days). Three FIV isolates were obtained in long-term macrophage (M Ø) cultures from two different cats.Therefore, M Ø from FIV-infected cats may harbor the virus for a long period of time and are able to transmit the virus to PBMC by cocultivation. FIV was also detected in bone marrow M Øs from one cat after seven weeks of culture. The results of these studies confirm the importance of macrophages for the persistence of FIV infection in cats.
Type of Medium:
Online Resource
ISSN:
0001-4192
Language:
French
Publisher:
PERSEE Program
Publication Date:
1993
detail.hit.zdb_id:
2840771-4
SSG:
22
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